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Kmo (NM_133809) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR207671L3V
- LentiORF®
-
Lenti ORF particles, Kmo (Myc-DDK-tagged) - Mouse kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (Kmo), 200ul, >10^7 TU/mL
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CNY 9,310.00
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Specifications
| Product Data | |
| Product Name | Kmo (NM_133809) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | AI046660 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_133809 |
| ORF Size | 1437 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR207671).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_133809.1, NP_598570.1 |
| RefSeq Size | 2512 bp |
| RefSeq ORF | 1440 bp |
| Locus ID | 98256 |
| Gene Summary | Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.[UniProtKB/Swiss-Prot Function] |
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