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Tbc1d23 (NM_026254) Mouse Tagged ORF Clone
CAT＃: MG210025
- TrueORF®
Tbc1d23 (tGFP-tagged) - Mouse TBC1 domain family, member 23 (Tbc1d23)
ORF Plasmid: DDK
"NM_026254" in other vectors (4)
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CNY 6,560.00
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | 4930451A13Rik; AU015720; AU043671; AU043778; D030022P07Rik; W51689 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG210025 representing NM_026254
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGAAGGAGAAGAGCTTCTGCCACTGTCAACGTCGGGCGGGGACAGCTGGGAAAAAGATCTTGAAG AAGCCCTTGAAGCAGGAGGTTGTGATCTTGAAACTTTGAGAAATATAATTCAAGGGAGGCCACTGCCTGC TGAGCTGAGGGCCAAGGTTTGGAAGATTGCTCTGAACGTTGCAGGGAAAGGTGATAGTTTGGCATCATGG GATGGTATTTTAGACTTGCCTGAGCAGAACACTATTCATAAAGATTGCCTTGAGTTTATCGAGCAGCTCT CAGTGCCAGAGGAGAAGGCAGCAGAATTACTCCTGGATATTGAATCTGTAATTACTTTTTACTGTAAATC ACGCAGCGTTAAATACAGCACATCCCTGAGCTGGATTCATCTACTGAAACCATTGATCTGTCTCCAGCTG CCTCGCAGCGACCTATACAACTGCTTCTATGCCGTCATGAATAAGTACATTCCCAGGGATTGTTCCCTGA AGGGGAGGCCATTTCATCTCTTCCGGTTGCTCATCCAGTACCACGAGCCTGAGCTTTGTTCTTTTCTTGA CACAAAGAAAATCACTCCAGACTCCTATGCACTCAACTGGCTCGGGAGCCTTTTTGCACATTACTGTTCC ACTGAGGTCACCCAGGCAATATGGGACGGATATCTACAGCAAGCGGACCCGTTTTTTATTTATTTCTTAA TGTTAATTATCCTTGTTAATACAAAAGAAGTTATTTTAGCACAAGAGTCTGACAGCAAAGAAGAAGTTAT CCGCTTTTTGGAAAGTACCCCGGCCAGCCTGAATCTGGAAGACATAGAAGACCTGTTCTCTTTGGCTCAG TATTACTGTAGTAAGACGCCAGCTTCTTTTAGGAAGGATAACCATCATCTCTTCGGTAGCACCCTGCTGG GGATCAAGGACGACGAGGCAGATCTGAGCCAGGCTCTGTGTCTGGCTGTTTCAGTATCAGAGATCCTTCA AGCTAATCAGCTGCAAGGGGAAGGAGTCCGGTTCTTCGTGGTGGACTGCCGTCCTGCGGAGCAGTACAAT GCTGGGCATTTGGCAACCGCGTTCCACCTAGACTCAGACTTGATGCTCCAGAATCCATCTGAGTTTGCAC AGTCAGTAAAGTCCTTGCTAGAAGCACAGAAACAGTCCATTGAGTCTGGCTCCATAGCAGGCGGGGAGCA CCTCTGTTTTATGGGCAGTGGCAGAGAGGAAGAAGACATGTACATGAACATGGTCCTCGCACACTTCTTA CAGAAAAACAAAGAATATGTTAGCATTGCCAGTGGAGGATTTATGGCCCTTCAGCAGCACCTGGCAGACA TAAATGTAGAGGGACCAGAAAGTGGATACGGCCATTGGATTGCCAGTACCTCAGGGTCAAGGGGCAGCAT CAGCTCTGTCGATGGTGAATCCTGTAATGGCTCCAATGATAGAGGAATGAAATCCCTGGTCAGTAAAATG ACTGTGGCTCTAAAGACAAAATCCGTTACCGTTAGGGAAAAGGTCATCAGCTTTATTGAGAACTCGTCGA CTCCTGTGGACCGGCACGTGAGCAGCAGCGACAGAGTGGGCAAGCCTTACCGTGGAGTGAAGCCTGTGTT CAGCATCGGCGATGAAGAGGAATATGACACAGATGAAATCGACAGCTCGTCCATGTCAGATGATGATAGG AAAGAGGTTGTCAACATCCAGACCTGGATCAACAAGCCGGACATCAAGCATCACTTTCCCTGTAAAGAAG TTAAAGAAAGTGGACATATGTTTCCTAGCCATCTGCTGGTTACCGCCACCCATATGTACTGCTTAAGGGA GATTCTTTCAAGGAAAGGCCTGGCTTACATCCAGTCTCGGCAAGCACTAAATTCTGTAGTGAAAATTACG TCCAAAAAAAAACATCCCGAGCTAATTACCTTCAAGTATGGAAACAGCAGTGCTTCCGGGATAGAAATCT TGGCTATTGAAAGGTATTTGATTCCAAATGCAGGAGATGCTACCAGAGCCATAAAACAGCAGATCATGAA AGTGTTGGATGCTTTGGAAAGT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG210025 representing NM_026254
Red=Cloning site Green=Tags(s) MAEGEELLPLSTSGGDSWEKDLEEALEAGGCDLETLRNIIQGRPLPAELRAKVWKIALNVAGKGDSLASW DGILDLPEQNTIHKDCLEFIEQLSVPEEKAAELLLDIESVITFYCKSRSVKYSTSLSWIHLLKPLICLQL PRSDLYNCFYAVMNKYIPRDCSLKGRPFHLFRLLIQYHEPELCSFLDTKKITPDSYALNWLGSLFAHYCS TEVTQAIWDGYLQQADPFFIYFLMLIILVNTKEVILAQESDSKEEVIRFLESTPASLNLEDIEDLFSLAQ YYCSKTPASFRKDNHHLFGSTLLGIKDDEADLSQALCLAVSVSEILQANQLQGEGVRFFVVDCRPAEQYN AGHLATAFHLDSDLMLQNPSEFAQSVKSLLEAQKQSIESGSIAGGEHLCFMGSGREEEDMYMNMVLAHFL QKNKEYVSIASGGFMALQQHLADINVEGPESGYGHWIASTSGSRGSISSVDGESCNGSNDRGMKSLVSKM TVALKTKSVTVREKVISFIENSSTPVDRHVSSSDRVGKPYRGVKPVFSIGDEEEYDTDEIDSSSMSDDDR KEVVNIQTWINKPDIKHHFPCKEVKESGHMFPSHLLVTATHMYCLREILSRKGLAYIQSRQALNSVVKIT SKKKHPELITFKYGNSSASGIEILAIERYLIPNAGDATRAIKQQIMKVLDALES TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_026254 |
| ORF Size | 2052 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_026254.2, NP_080530.2 |
| RefSeq Size | 3664 bp |
| RefSeq ORF | 2055 bp |
| Locus ID | 67581 |
| UniProt ID | Q8K0F1 |
| Gene Summary | Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles (PubMed:29084197). Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1 (By similarity). Plays a role in brain development, including in cortical neuron positioning. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes which are essential for axonal and dendritic growth (PubMed:28823707). May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge (PubMed:22312129).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC204503 | Tbc1d23 (untagged) - Mouse TBC1 domain family, member 23 (Tbc1d23), (10ug) |
CNY 5,016.00 |
|
| MR210025 | Tbc1d23 (Myc-DDK-tagged) - Mouse TBC1 domain family, member 23 (Tbc1d23) |
CNY 5,016.00 |
|
| MR210025L3 | Lenti ORF clone of Tbc1d23 (Myc-DDK-tagged) - Mouse TBC1 domain family, member 23 (Tbc1d23) |
CNY 7,890.00 |
|
| MR210025L4 | Lenti ORF clone of Tbc1d23 (mGFP-tagged) - Mouse TBC1 domain family, member 23 (Tbc1d23) |
CNY 7,890.00 |
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