Homer2 (NM_001164087) Mouse Tagged ORF Clone
CAT#: MG218531
- TrueORF®
Homer2 (tGFP-tagged) - Mouse homer homolog 2 (Drosophila) (Homer2) transcript variant 3, (10ug)
ORF Plasmid: DDK
"NM_001164087" in other vectors (4)
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CNY 3,140.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | 9330120H11Rik; AW539445; CPD; Vesl-2 |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MG218531 representing NM_001164087
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACTTTCACCAAAACGTCACAGAAGTTCGGGCAGTGGGCTGACAGCAGAGCCAACACCGTGTTCGGTT TGGGATTCTCCTCCGAGCTGCAGCTCACGAAGTTTGCAGAGAAGTTCCAGGAGGTAAGAGAAGCTGCCAG GCTAGCCAGAGACAAGTCCCAGGAGAAAACCGAGACCTCCAGCAATCATTCCCAAGAATCTGGGTGTGAA ACCCCGTCTTCCACTCAGGCATCCAGCGTCAATGGCACAGACGACGAAAAGGCCTCTCACGCGAGCCCAG CCGACACTCACCTCAAGTCTGAGAATGACAAGCTGAAGATCGCGCTGACACAGAGTGCTGCCAATGTGAA GAAGTGGGAGATGGAGCTGCAGACCCTGCGGGAGAGCAACGCCCGGCTGACCACGGCACTGCAGGAGTCG GCGGCCAGCGTGGAGCAGTGGAAGCGGCAGTTCTCCATCTGCAGGGACGAGAATGACAGGCTCCGCAGCA AGATCGAGGAGCTGGAAGAACAGTGCAGCGAGATAAACAGGGAGAAGGAGAAGAACACACAGCTGAAGAG GAGGATCGAGGAGCTGGAGTCAGAGGTCCGAGACAAGGAGATGGAGTTGAAAGATCTCCGAAAACAGAGT GAAATCATACCTCAGCTCATGTCCGAGTGTGAATATGTCTCTGAGAAGTTAGAGGCGGCCGAAAGAGACA ATCAAAACTTGGAAGACAAAGTGCGGTCTCTAAAGACAGACATCGAGGAGAGTAAATACCGACAGCGCCA CCTGAAGGGGGAGCTGAAGAGCTTCCTTGAGGTGCTGGATGGAAAGATCGACGACCTCCATGACTTCCGT AGAGGACTCTCCAAGTTAGGCACAGATAAC ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG218531 representing NM_001164087
Red=Cloning site Green=Tags(s) MTFTKTSQKFGQWADSRANTVFGLGFSSELQLTKFAEKFQEVREAARLARDKSQEKTETSSNHSQESGCE TPSSTQASSVNGTDDEKASHASPADTHLKSENDKLKIALTQSAANVKKWEMELQTLRESNARLTTALQES AASVEQWKRQFSICRDENDRLRSKIEELEEQCSEINREKEKNTQLKRRIEELESEVRDKEMELKDLRKQS EIIPQLMSECEYVSEKLEAAERDNQNLEDKVRSLKTDIEESKYRQRHLKGELKSFLEVLDGKIDDLHDFR RGLSKLGTDN TRTRPLE - GFP Tag - V |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_001164087 |
ORF Size | 870 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001164087.1, NP_001157559.1 |
RefSeq Size | 10982 bp |
RefSeq ORF | 873 bp |
Locus ID | 26557 |
UniProt ID | Q9QWW1 |
Gene Summary | Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2 (By similarity). Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses (By similarity) Required for normal hearing (PubMed:25816005). Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway. Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC209736 | Homer2 (untagged) - Mouse homer homolog 2 (Drosophila) (Homer2), transcript variant 3, (10ug) |
CNY 3,990.00 |
|
MR218531 | Homer2 (Myc-DDK-tagged) - Mouse homer homolog 2 (Drosophila) (Homer2), transcript variant 3 |
CNY 2,850.00 |
|
MR218531L3 | Lenti ORF clone of Homer2 (Myc-DDK-tagged) - Mouse homer homolog 2 (Drosophila) (Homer2), transcript variant 3 |
CNY 4,750.00 |
|
MR218531L4 | Lenti ORF clone of Homer2 (mGFP-tagged) - Mouse homer homolog 2 (Drosophila) (Homer2), transcript variant 3 |
CNY 4,750.00 |