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Dyrk1b (NM_001037957) Mouse Tagged ORF Clone
CAT＃: MR209588
- TrueORF®
Dyrk1b (Myc-DDK-tagged) - Mouse dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 1
ORF Plasmid: tGFP
"NM_001037957" in other vectors (4)
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CNY 4,680.00
CNY 5,510.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | Mirk |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR209588 representing NM_001037957
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCGTCCCACCAGGCCATGGTCCTTTCTCTGGCTTTCCGGGGCCCCAGGAACACACACAGGTACTAC CTGATGTGCGGCTCCTGCCCCGGAGACTGCCCCTGGCCTTCCGGGATGCGGCCTCAGCCCCGCTGCGCAA GCTCTCGGTGGACCTCATCAAGACCTACAAGCACATCAATGAGGTATACTATGCGAAGAAGAAGCGGCGG GCCCAACAGGCGCCACCCCAGGACTCGAGCACCAAAAAGGAGAAGAAGGTCCTGAACCACGGTTATGATG ACGACAACCACGACTACATTGTGCGCAGTGGCGAGCGCTGGCTAGAGCGCTATGAGATTGACTCTCTTAT TGGCAAAGGCTCCTTTGGCCAGGTGGTGAAAGCCTATGATCACCAGACTCAGGAGCTGGTGGCCATCAAG ATCATCAAGAACAAAAAGGCCTTCCTGAACCAGGCACAGATTGAGCTACGGCTGTTGGAGCTGATGAACC AGCATGATACAGAGATGAAGTACTACATAGTACACCTTAAGCGGCACTTCATGTTCCGGAATCACCTGTG CCTGGTGTTTGAGCTGCTGTCCTACAACCTGTACGACCTCCTCCGCAACACACACTTTCGGGGTGTCTCA CTGAACCTGACGAGGAAGCTGGCACAGCAGCTCTGCACAGCTCTGCTCTTTCTGGCCACCCCCGAGCTCA GCATCATCCACTGCGACCTCAAGCCTGAGAACATCCTGCTCTGCAACCCCAAGCGCAGTGCCATCAAGAT CGTGGACTTCGGCAGTTCCTGCCAGCTTGGCCAGCGGATCTACCAGTATATCCAGAGCCGCTTCTACCGC TCACCCGAGGTGCTCCTGGGTACACCCTATGACCTGGCCATTGACATGTGGTCCCTGGGCTGCATCCTCG TGGAGATGCACACCGGAGAGCCCCTCTTCAGTGGCTCTAATGAGGTGGACCAGATGAGCCGTATTGTGGA GGTGTTGGGCATCCCTCCCGCACCCATGCTGGAACAGGCACCCAAGGCTCGAAAGTACTTTGAGCGGCTG CCTGGGGGTGGCTGGACCCTACGAAGGACAAAGGAACTCAGGAAGGATTACCAGGGCCCTGGGACACGGC GGCTGCAGGAGGTGCTGGGCGTGCAGACGGGCGGGCCCGGGGGCCGGCGGGCGGGGGAGCCCGGCCACAG CCCCGCCGACTACCTCCGCTTCCAGGACCTGGTGCTGCGCATGCTGGAATATGAGCCCGCCGCCCGCATC AGCCCTCTGGGCGCTCTGCAGCATGGCTTCTTCCGCCGCACGGCCGACGAGGCCACCAACACGGGCCCGG CAGGCAGCAGTGCCTCCACCTCGCCGGCGCCCCTTGACACCTGCCCCTCCTCTAGCACCGCCAGCTCCAT CTCCAGCTCTGGAGGTTCCAGTGGCTCCTCCAACGACAACAGAGCCTACCGATACAGCAACCGATATTGT GGGGGCCCAGGGCCCCCCATCACTGACTGTGAGATGAACAGCCCCCAGGTCCTACCCTCCCAGCCTCTGC GCCCCTGGGCAGGGGGTGATGTGCCCCACAAGACACATCAAGCCCCTATCTCTGCCTCAACATTGCCGGG GACTGGGGCTCAGTTACCCCCATTGCCCCGTTGCCTTGGACGACCCCCATCACCAACATCACCACCACCC CCAGAGTTGATGGATGTGAGCCTGGTGGGCAGCCCTCCAGACTGCTCTCCACCTCCTCCAGCACCTGCCC CCCAGCACCCGGCTGCCTCAGCCCTCCGGACTCGGATGACAGGAGGTCGACCACCTCTCCCACCCCCTGA TGACCCTGCCACTCTGGGGCCTCGCCTGGGTCTCCATGGTGTACCCCAGAGCACAGCAGCCAGCTCA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR209588 representing NM_001037957
Red=Cloning site Green=Tags(s) MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDAASAPLRKLSVDLIKTYKHINEVYYAKKKRR AQQAPPQDSSTKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKGSFGQVVKAYDHQTQELVAIK IIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHFMFRNHLCLVFELLSYNLYDLLRNTHFRGVS LNLTRKLAQQLCTALLFLATPELSIIHCDLKPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYR SPEVLLGTPYDLAIDMWSLGCILVEMHTGEPLFSGSNEVDQMSRIVEVLGIPPAPMLEQAPKARKYFERL PGGGWTLRRTKELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARI SPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSNDNRAYRYSNRYC GGPGPPITDCEMNSPQVLPSQPLRPWAGGDVPHKTHQAPISASTLPGTGAQLPPLPRCLGRPPSPTSPPP PELMDVSLVGSPPDCSPPPPAPAPQHPAASALRTRMTGGRPPLPPPDDPATLGPRLGLHGVPQSTAASS TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001037957 |
| ORF Size | 1887 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001037957.3, NP_001033046.1 |
| RefSeq Size | 2524 bp |
| RefSeq ORF | 1890 bp |
| Locus ID | 13549 |
| UniProt ID | Q9Z188 |
| MW | 69.6 kDa |
| Gene Summary | Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activity. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC219899 | Dyrk1b (untagged) - Mouse dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 1, (10ug) |
CNY 8,080.00 |
|
| MG209588 | Dyrk1b (tGFP-tagged) - Mouse dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 1 |
CNY 6,080.00 |
|
| MR209588L3 | Lenti ORF clone of Dyrk1b (Myc-DDK-tagged) - Mouse dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 1 |
CNY 7,410.00 |
|
| MR209588L4 | Lenti ORF clone of Dyrk1b (mGFP-tagged) - Mouse dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b (Dyrk1b), transcript variant 1 |
CNY 7,410.00 |
