Mapk8ip3 (NM_001163447) Mouse Tagged ORF Clone
CAT#: MR211934
- TrueORF®
Mapk8ip3 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 2
"NM_001163447" in other vectors (3)
Need custom modification / cloning service?
Get a free quote
CNY 13,300.00
CNY 300.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | BB120594; D17Wsu15e; JIP-3; Jip3; JSAP1; JSAP1a; JSAP1b; JSAP1c; JSAP1d; mKIAA1066; Syd2 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR211934 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGATGGAGATCCAGATGGACGAGGGAGGAGGAGTGGTGGTGTACCAAGACGACTACTGCTCGGGCTCGG TCATGTCGGAGCGTGTGTCGGGCCTGGCGGGCTCCATCTACCGCGAGTTCGAGCGCCTCATTCACTGCTA TGACGAGGAGGTGGTCAAGGAGCTCATGCCGCTGGTGGTGAACGTGCTGGAGAACCTTGACTCGGTGCTG AGCGAGAACCAGGAGCACGAGGTGGAGCTGGAGCTCCTACGCGAGGACAACGAGCAGCTGCTCACGCAAT ACGAGCGCGAGAAGGCGCTGCGCAAACAGGCCGAGGAGAAATTCATCGAATTTGAAGATGCCTTGGAACA AGAGAAGAAAGAACTCCAGATCCAGGTAGAACATTATGAGTTTCAGACACGCCAGCTGGAGCTAAAGGCC AAAAACTATGCAGATCAGATTTCCCGACTGGAGGAACGAGAATCGGAGATGAAGAAGGAATACAATGCCC TGCACCAGCGGCACACAGAGATGATCCAGACCTATGTGGAACACATTGAAAGATCCAAGATGCAGCAAGT TGGGGGTAGCGGCCAAACAGAAAGCAGCCTGCCCGGGCGGAGGAAGGAGCGTCCCACCTCTCTGAATGTC TTCCCCCTGGCTGATGGCATGGTACGTGCACAGATGGGGGGCAAGCTCGTGCCTGCGGGGGACCACTGGC ACCTGAGTGACCTCGGCCAGCTACAGTCCAGCTCCAGCTACCAGTGTCCAAATGATGAGATGTCTGAGTC AGGCCAGTCCTCAGCAGCTGCAACACCCAGTACCACAGGTACCAAGTCCAACACACCCACGTCCTCCGTG CCCTCAGCAGCAGTCACGCCACTCAACGAGAGCCTACAGCCCCTGGGGGACTATGTCAGTGTCACAAAGA ACAACAAGCAGGCCCGAGAGAAGCGCAATAGCCGTAACATGGAGGTCCAGGTCACCCAAGAGATGCGGAA CGTCAGTATCGGCATGGGCAGCAGTGACGAGTGGTCCGATGTTCAGGACATTATCGACTCCACCCCAGAG CTGGATGTGTGTCCTGAAACCCGTCTGGAGCGCACAGGAAGCAGCCCAACCCAGGGAATTGTAAACAAAG CTTTTGGAATCAACACTGACTCCTTGTATCACGAACTCTCCACGGCGGGATCTGAGGTCATCGGGGATGT GGACGAGGGAGCTGATCTCCTAGGGGAGTTTTCAGTGCGCGATGATTTTTTTGGAATGGGCAAAGAAGTG GGGAACCTGCTGCTGGAGAACTCACAGCTTCTAGAGACAAAAAATGCTTTAAATGTAGTGAAGAATGACC TCATTGCTAAGGTTGACCAACTGTCAGGAGAACAGGAGGTCCTGAAGGGTGAGCTGGAAGCAGCCAAGCA AGCCAAAGTCAAGCTGGAGAACCGAATCAAAGAGCTTGAAGAAGAACTGAAGAGAGTCAAGTCAGAGGCA GTAACTGCCCGCCGTGAGCCCAGAGAAGAGGTGGAGGATGTAAGCAGCTATCTCTGTACAGAATTGGACA AAATCCCCATGGCCCAGCGCCGACGCTTCACACGGGTGGAGATGGCCCGAGTGCTCATGGAACGCAACCA GTACAAGGAACGCCTCATGGAGCTGCAGGAGGCTGTGAGGTGGACTGAAATGATCAGAGCATCAAGGGAA CACCCATCTGTCCAGGAGAAGAAGAAGTCCACCATCTGGCAGTTCTTTAGTCGCCTCTTCAGCTCCTCAT CTAGCCCCCCTCCGGCCAAACGATCCTACCCATCTGTGAACATTCACTACAAGTCACCCACTGCAGCTGG CTTTAGCCAGCGTCGCAGCCATGCTTTGTGCCAGATCTCAGCCGGCAGCAGGCCCCTGGAGTTCTTCCCT GATGATGACTGCACCTCTTCTGCCCGGCGGGAGCAGAAGCGGGAGCAGTACCGCCAGGTTCGTGAACACG TGCGCAATGATGACGGGAGGCTGCAGGCCTGTGGGTGGAGCCTGCCTGCCAAGTACAAGCAGCTGAGCCC CAATGGAGGCCAGGAAGACACCCGGATGAAAAATGTGCCTGTCCCTGTGTACTGCCGCCCTCTGGTGGAG AAGGACCCTTCGACAAAGCTGTGGTGTGCTGCTGGTGTCAACCTGAGTGGGTGGAAGCCACATGAAGAGG ACTCTAGCAATGGACCCAAGCCTGTACCAGGTCGAGACCCTCTGACCTGTGACCGGGAAGGAGAAGGCGA ACCCAAGAGCACACACCCATCACCTGAGAAGAAGAAGGCAAAGGAAACCCCTGAGGCAGATGCTACCTCC AGTCGGGTATGGATCCTCACCAGCACCCTGACAACCAGCAAGGTGGTGATCATTGATGCCAACCAGCCAG GCACAATTGTGGATCAGTTCACAGTCTGCAATGCCCACGTCCTGTGTATCTCCAGCATTCCTGCGGCCAG TGACAGTGACTATCCCCCTGGGGAGATGTTCCTAGACAGTGATGTGAACCCTGAAGATTCAGGTGCTGAT GGTGTGCTGGCTGGCATCACCCTGGTGGGGTGTGCTACCCGCTGCAATGTTCCACGTAGCAACTGTTCCT CACGAGGAGACACCCCAGTACTGGACAAGGGGCAGGGGGATGTGGCGACCACTGCCAATGGGAAGGTCAA CCCGTCCCAATCCACAGAAGAAGCCACAGAAGCCACGGAGGTGCCAGACCCTGGTCCCAGCGAGTCAGAA GCAACGACAGTCCGGCCCGGGCCTCTCACAGAGCATGTCTTTACTGACCCAGCACCCACCCCATCCTCCA GCACCCAGCCTGCCAGTGAGAATGGGTCAGAGTCCAATGGCACCATTGTACAGCCTCAGGTGGAGCCCAG TGGGGAACTCTCAACAACAACCAGTAGCGCTGCACCCACTATGTGGCTAGGAGCCCAGAATGGCTGGCTC TATGTGCATTCAGCGGTAGCCAACTGGAAGAAGTGTCTGCACTCCATCAAGCTAAAAGACTCTGTGCTGA GCCTGGTGCATGTCAAAGGCCGAGTGCTGGTAGCTCTTGCAGATGGGACCCTGGCTATCTTCCATCGTGG AGAGGATGGCCAGTGGGACCTGAGCAACTACCACCTAATGGACCTGGGCCACCCACACCACTCCATCCGC TGCATGGCTGTTGTGAATGACCGAGTTTGGTGTGGCTACAAGAACAAGGTGCATGTTATCCAGCCCAAGA CAATGCAGATTGAGAAATCATTTGATGCCCACCCAAGGCGGGAAAGCCAGGTACGTCAGCTGGCCTGGAT CGGTGATGGAGTGTGGGTCTCTATTCGCTTGGATTCTACCCTTCGGCTCTACCATGCTCACACCCACCAG CACCTGCAGGATGTGGACATTGAGCCCTATGTTAGCAAGATGCTAGGAACCGGCAAGCTGGGCTTCTCCT TCGTGCGCATCACAGCCTTACTCATTGCAGGCAACCGTCTGTGGGTGGGCACTGGCAATGGGGTTGTCAT CTCCATCCCCTTGACTGAGACTGTGGTCCTGCATCGAGGCCAGCTCCTAGGGCTCCGAGCCAACAAGACA TCCCCAACATCTGGGGAGGGGACCCGCCCAGGGGGCATCATCCATGTGTATGGGGACGACAGCAGTGACA AGGCCGCCAGTAGTTTCATCCCCTACTGCTCCATGGCACAGGCTCAGCTTTGCTTCCATGGGCACCGTGA TGCTGTCAAATTCTTTGTCTCTGTGCCAGGAAATGTGCTGGCCACTCTCAATGGCAGTGTGCTAGACAGC CCATCAGAGGGCCCTGGGCCTGCTGCACCCGCTGCAGATGCTGAGGGCCAGAAGTTGAAGAATGCACTGG TGCTGAGTGGTGGTGAAGGTTACATTGACTTCCGTATCGGAGACGGAGAGGATGATGAAACTGAGGAATG TGCCGGGGACGTGAACCAGACAAAGCCCTCGTTGTCCAAGGCTGAGCGCAGCCACATCATCGTGTGGCAG GTGTCCTACACCCCTGAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR211934 protein sequence
Red=Cloning site Green=Tags(s) MMEIQMDEGGGVVVYQDDYCSGSVMSERVSGLAGSIYREFERLIHCYDEEVVKELMPLVVNVLENLDSVL SENQEHEVELELLREDNEQLLTQYEREKALRKQAEEKFIEFEDALEQEKKELQIQVEHYEFQTRQLELKA KNYADQISRLEERESEMKKEYNALHQRHTEMIQTYVEHIERSKMQQVGGSGQTESSLPGRRKERPTSLNV FPLADGMVRAQMGGKLVPAGDHWHLSDLGQLQSSSSYQCPNDEMSESGQSSAAATPSTTGTKSNTPTSSV PSAAVTPLNESLQPLGDYVSVTKNNKQAREKRNSRNMEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPE LDVCPETRLERTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGEFSVRDDFFGMGKEV GNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLKGELEAAKQAKVKLENRIKELEEELKRVKSEA VTARREPREEVEDVSSYLCTELDKIPMAQRRRFTRVEMARVLMERNQYKERLMELQEAVRWTEMIRASRE HPSVQEKKKSTIWQFFSRLFSSSSSPPPAKRSYPSVNIHYKSPTAAGFSQRRSHALCQISAGSRPLEFFP DDDCTSSARREQKREQYRQVREHVRNDDGRLQACGWSLPAKYKQLSPNGGQEDTRMKNVPVPVYCRPLVE KDPSTKLWCAAGVNLSGWKPHEEDSSNGPKPVPGRDPLTCDREGEGEPKSTHPSPEKKKAKETPEADATS SRVWILTSTLTTSKVVIIDANQPGTIVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDSGAD GVLAGITLVGCATRCNVPRSNCSSRGDTPVLDKGQGDVATTANGKVNPSQSTEEATEATEVPDPGPSESE ATTVRPGPLTEHVFTDPAPTPSSSTQPASENGSESNGTIVQPQVEPSGELSTTTSSAAPTMWLGAQNGWL YVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGTLAIFHRGEDGQWDLSNYHLMDLGHPHHSIR CMAVVNDRVWCGYKNKVHVIQPKTMQIEKSFDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQ HLQDVDIEPYVSKMLGTGKLGFSFVRITALLIAGNRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKT SPTSGEGTRPGGIIHVYGDDSSDKAASSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDS PSEGPGPAAPAADAEGQKLKNALVLSGGEGYIDFRIGDGEDDETEECAGDVNQTKPSLSKAERSHIIVWQ VSYTPE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
![]() |
ACCN | NM_001163447 |
ORF Size | 4008 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq Size | 5576 bp |
RefSeq ORF | 4011 bp |
Locus ID | 30957 |
UniProt ID | Q9ESN9 |
MW | 147.5 kDa |
Gene Summary | The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins (PubMed:10523642, PubMed:10629060). Promotes neuronal axon elongation in a kinesin- and JNK-dependent manner (PubMed:23576431, PubMed:25944905, PubMed:28259553). Activates cofilin at axon tips via local activation of JNK, thereby regulating filopodial dynamics and enhancing axon elongation (PubMed:23576431, PubMed:25944905, PubMed:28259553). Its binding to kinesin heavy chains (KHC), promotes kinesin-1 motility along microtubules and is essential for axon elongation and regeneration (PubMed:23576431, PubMed:25944905, PubMed:28259553). Regulates cortical neuronal migration by mediating NTRK2/TRKB anterograde axonal transport during brain development (PubMed:23576431, PubMed:25944905, PubMed:28259553). Acts as an adapter that bridges the interaction between NTRK2/TRKB and KLC1 and drives NTRK2/TRKB axonal but not dendritic anterograde transport, which is essential for subsequent BDNF-triggered signaling and filopodia formation (PubMed:23576431, PubMed:25944905, PubMed:28259553).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC224579 | Mapk8ip3 (untagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 2, (10ug) |
CNY 19,190.00 |
|
MR211934L3 | Lenti ORF clone of Mapk8ip3 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 2 |
CNY 15,200.00 |
|
MR211934L4 | Lenti ORF clone of Mapk8ip3 (mGFP-tagged) - Mouse mitogen-activated protein kinase 8 interacting protein 3 (Mapk8ip3), transcript variant 2 |
CNY 15,200.00 |
其它Mapk8ip3产品