Bmpr1a (NM_009758) Mouse Tagged ORF Clone
CAT#: MR227586
- TrueORF®
Bmpr1a (Myc-DDK-tagged) - Mouse bone morphogenetic protein receptor, type 1A (Bmpr1a)
ORF Plasmid: tGFP
"NM_009758" in other vectors (4)
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CNY 3,960.00
CNY 4,560.00
Cited in 1 publication. |
CNY 300.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | 1110037I22Rik; ALK3; AU045487; Bmpr; BMPR-IA |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MR227586 representing NM_009758
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACTCAGCTATACACTTACATCAGATTACTGGGAGCCTGTCTGTTCATCATTTCTCATGTTCAAGGGC AGAATCTAGATAGTATGCTCCATGGCACTGGTATGAAATCAGACTTGGACCAGAAGAAGCCAGAAAATGG AGTGACTTTAGCACCAGAGGATACCTTGCCTTTCTTAAAGTGCTATTGCTCAGGACACTGCCCAGATGAT GCTATTAATAACACATGCATAACTAATGGCCATTGCTTTGCCATTATAGAAGAAGATGATCAGGGAGAAA CCACATTAACTTCTGGGTGTATGAAGTATGAAGGCTCTGATTTTCAATGCAAGGATTCACCGAAAGCCCA GCTACGCAGGACAATAGAATGTTGTCGGACCAATTTGTGCAACCAGTATTTGCAGCCTACACTGCCCCCT GTTGTTATAGGTCCGTTCTTTGATGGCAGCATCCGATGGCTGGTTGTGCTCATTTCCATGGCTGTCTGTA TAGTTGCTATGATCATCTTCTCCAGCTGCTTTTGCTATAAGCATTATTGTAAGAGTATCTCAAGCAGGGG TCGTTACAACCGTGATTTGGAACAGGATGAAGCATTTATTCCAGTAGGAGAATCATTGAAAGACCTGATT GACCAGTCCCAAAGCTCTGGGAGTGGATCTGGATTGCCTTTATTGGTTCAGCGAACTATTGCCAAACAGA TTCAGATGGTTCGGCAGGTTGGTAAAGGCCGCTATGGAGAAGTATGGATGGGTAAATGGCGTGGTGAAAA AGTGGCTGTCAAAGTGTTTTTTACCACTGAAGAAGCTAGCTGGTTTAGAGAAACAGAAATCTACCAGACG GTGTTAATGCGTCATGAAAATATACTTGGTTTTATAGCTGCAGACATTAAAGGCACTGGTTCCTGGACTC AGCTGTATTTGATTACTGATTACCATGAAAATGGATCTCTCTATGACTTCCTGAAATGTGCCACACTAGA CACCAGAGCCCTACTCAAGTTAGCTTATTCTGCTGCTTGTGGTCTGTGCCACCTCCACACAGAAATTTAT GGTACCCAAGGGAAGCCTGCAATTGCTCATCGAGACCTGAAGAGCAAAAACATCCTTATTAAGAAAAATG GAAGTTGCTGTATTGCTGACCTGGGCCTAGCTGTTAAATTCAACAGTGATACAAATGAAGTTGACATACC CTTGAATACCAGGGTGGGCACCAAGCGGTACATGGCTCCAGAAGTGCTGGATGAAAGCCTGAATAAAAAC CATTTCCAGCCCTACATCATGGCTGACATCTATAGCTTTGGTTTGATCATTTGGGAAATGGCTCGTCGTT GTATTACAGGAGGAATCGTGGAGGAATATCAATTACCATATTACAACATGGTGCCCAGTGACCCATCCTA TGAGGACATGCGTGAGGTTGTGTGTGTGAAACGCTTGCGGCCAATCGTGTCTAACCGCTGGAACAGCGAT GAATGTCTTCGAGCAGTTTTGAAGCTAATGTCAGAATGTTGGGCCCATAATCCAGCCTCCAGACTCACAG CTTTGAGAATCAAGAAGACACTTGCAAAAATGGTTGAATCCCAGGATGTAAAGATT ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR227586 representing NM_009758
Red=Cloning site Green=Tags(s) MTQLYTYIRLLGACLFIISHVQGQNLDSMLHGTGMKSDLDQKKPENGVTLAPEDTLPFLKCYCSGHCPDD AINNTCITNGHCFAIIEEDDQGETTLTSGCMKYEGSDFQCKDSPKAQLRRTIECCRTNLCNQYLQPTLPP VVIGPFFDGSIRWLVVLISMAVCIVAMIIFSSCFCYKHYCKSISSRGRYNRDLEQDEAFIPVGESLKDLI DQSQSSGSGSGLPLLVQRTIAKQIQMVRQVGKGRYGEVWMGKWRGEKVAVKVFFTTEEASWFRETEIYQT VLMRHENILGFIAADIKGTGSWTQLYLITDYHENGSLYDFLKCATLDTRALLKLAYSAACGLCHLHTEIY GTQGKPAIAHRDLKSKNILIKKNGSCCIADLGLAVKFNSDTNEVDIPLNTRVGTKRYMAPEVLDESLNKN HFQPYIMADIYSFGLIIWEMARRCITGGIVEEYQLPYYNMVPSDPSYEDMREVVCVKRLRPIVSNRWNSD ECLRAVLKLMSECWAHNPASRLTALRIKKTLAKMVESQDVKI TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_009758 |
ORF Size | 1596 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_009758.4, NP_033888.2 |
RefSeq Size | 5481 bp |
RefSeq ORF | 1599 bp |
Locus ID | 12166 |
UniProt ID | P36895 |
MW | 60.5 kDa |
Gene Summary | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction (PubMed:24098149). Mediates induction of adipogenesis by GDF6 (PubMed:23527555).[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Heparan sulfate antagonism alters bone morphogenetic protein signaling and receptor dynamics, suggesting a mechanism in Hereditary Multiple Exostoses
,Mundy, C;Yang, E;Takano, H;Billings, PC;Pacifici, M;,
J. Biol. Chem.
,PubMed ID 29622677
[BMPR1A]
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Documents
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC217555 | Bmpr1a (untagged) - Mouse bone morphogenetic protein receptor, type 1A (Bmpr1a), (10ug) |
CNY 3,968.00 |
|
MG227586 | Bmpr1a (tGFP-tagged) - Mouse bone morphogenetic protein receptor type 1A (Bmpr1a), (10ug) |
CNY 5,040.00 |
|
MR227586L3 | Lenti ORF clone of Bmpr1a (Myc-DDK-tagged) - Mouse bone morphogenetic protein receptor, type 1A (Bmpr1a) |
CNY 6,360.00 |
|
MR227586L4 | Lenti ORF clone of Bmpr1a (mGFP-tagged) - Mouse bone morphogenetic protein receptor, type 1A (Bmpr1a) |
CNY 6,360.00 |