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LXN (NM_020169) Human Tagged ORF Clone
CAT＃: RC202769
LXN (Myc-DDK-tagged)-Human latexin (LXN)
ORF Plasmid: tGFP
"NM_020169" in other vectors (7)
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CNY 2,400.00
CNY 3,705.00
| Cited in 2 publications. |
Product images
CNY 300.00
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | ECI; TCI |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC202769 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAAATCCCGCCGACCAACTACCCAGCCTCCAGGGCGGCCTTGGTGGCACAGAACTACATCAACTACC AGCAGGGGACCCCGCACAGGGTGTTTGAGGTGCAGAAGGTCAAACAAGCCAGCATGGAGGATATTCCAGG AAGAGGACATAAGTATCGCCTTAAATTTGCTGTTGAAGAAATTATACAAAAACAAGTTAAGGTGAACTGC ACAGCTGAAGTACTTTACCCTTCAACGGGACAAGAAACTGCACCAGAAGTCAACTTCACATTTGAAGGAG AAACTGGAAAGAATCCAGATGAAGAAGACAACACATTTTATCAAAGACTTAAGTCCATGAAGGAACCGCT AGAAGCACAAAATATTCCAGACAATTTTGGAAATGTATCTCCAGAAATGACGCTCGTTCTACATTTAGCC TGGGTTGCCTGTGGTTATATAATATGGCAAAATTCTACTGAAGACACATGGTATAAAATGGTAAAAATTC AAACTGTCAAGCAAGTGCAAAGAAATGATGACTTTATTGAATTAGACTACACCATTCTACTTCATAATAT AGCATCTCAGGAGATTATTCCCTGGCAAATGCAAGTTCTCTGGCATCCACAATACGGCACTAAAGTAAAA CATAATAGCCGTCTGCCAAAGGAAGTACAACTGGAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC202769 protein sequence
Red=Cloning site Green=Tags(s) MEIPPTNYPASRAALVAQNYINYQQGTPHRVFEVQKVKQASMEDIPGRGHKYRLKFAVEEIIQKQVKVNC TAEVLYPSTGQETAPEVNFTFEGETGKNPDEEDNTFYQRLKSMKEPLEAQNIPDNFGNVSPEMTLVLHLA WVACGYIIWQNSTEDTWYKMVKIQTVKQVQRNDDFIELDYTILLHNIASQEIIPWQMQVLWHPQYGTKVK HNSRLPKEVQLE TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_020169 |
| ORF Size | 666 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_020169.2, NP_064554.2 |
| RefSeq Size | 1132 bp |
| RefSeq ORF | 669 bp |
| Locus ID | 56925 |
| UniProt ID | Q9BS40 |
| MW | 25.8 kDa |
| Gene Summary | This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases. The encoded protein, latexin, downregulates the population size of hematopoietic stem cells. This protein is found to be downregulated in cancer cells because of promoter hypermethylation. [provided by RefSeq, Jul 2020] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Bone Microenvironment Changes in Latexin Expression Promote Chemoresistance
,Zhang, M;Osisami, M;Dai, J;Keller, JM;Escara-Wilke, J;Mizokami, A;Keller, ET;,
Mol. Cancer Res
,PubMed ID 28087740
[LXN]
|
|
Latexin exhibits tumor-suppressor potential in pancreatic ductal adenocarcinoma
,null,
Oncology Reports
,PubMed ID 26530530
[LXN]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202769L1 | Lenti ORF clone of Human latexin (LXN), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC202769L2 | Lenti ORF clone of Human latexin (LXN), mGFP tagged |
CNY 5,890.00 |
|
| RC202769L3 | Lenti ORF clone of Human latexin (LXN), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202769L4 | Lenti ORF clone of Human latexin (LXN), mGFP tagged |
CNY 5,890.00 |
|
| RG202769 | LXN (tGFP-tagged) - Human latexin (LXN) |
CNY 4,000.00 |
|
| SC113204 | LXN (untagged)-Human latexin (LXN) |
CNY 2,400.00 |
|
| SC320767 | LXN (untagged)-Human latexin (LXN) |
CNY 2,400.00 |
