CTRB1 (NM_001906) Human Tagged Lenti ORF Clone
CAT#: RC202806L1
- LentiORF®
Lenti ORF clone of Human chymotrypsinogen B1 (CTRB1), Myc-DDK-tagged
"NM_001906" in other vectors (6)
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CNY 4,800.00
CNY 5,890.00
CNY 600.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | CTRB |
Vector | pLenti-C-Myc-DDK |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC202806).
|
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001906 |
ORF Size | 789 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001906.4 |
RefSeq Size | 873 bp |
RefSeq ORF | 792 bp |
Locus ID | 1504 |
UniProt ID | P17538 |
Protein Families | Druggable Genome, Protease, Secreted Protein, Transmembrane |
MW | 27.9 kDa |
Gene Summary | This gene encodes a member of the serine protease family of enzymes and forms a principal precursor of the pancreatic proteolytic enzymes. The encoded preproprotein is synthesized in the acinar cells of the pancreas and secreted into the small intestine where it undergoes proteolytic activation to generate a functional enzyme. This CTRB1 gene is located head-to-head with the related CTRB2 gene. Some human populations have an alternate haplotype which inverts a 16.6 Kb region containing portions of intron 1, exon 1, and the upstream sequence of the CTRB1 and CTRB2 genes. In this inversion haplotype exon 1 and flanking sequence is swapped in CTRB1 and CTRB2. This inversion is associated with differential gene expression and increased risk for chronic pancreatitis. The GRCh38 assembly represents the minor allele for SNP rs8048956 of the CTRB1 gene. SNP rs8048956 in intron 1 of the CTRB2 gene is diagnostic for this inversion. This CTRB1 gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein. [provided by RefSeq, Jan 2021] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC202806 | CTRB1 (Myc-DDK-tagged)-Human chymotrypsinogen B1 (CTRB1) |
CNY 2,400.00 |
|
RC202806L2 | Lenti ORF clone of Human chymotrypsinogen B1 (CTRB1), mGFP tagged |
CNY 5,890.00 |
|
RC202806L3 | Lenti ORF clone of Human chymotrypsinogen B1 (CTRB1), Myc-DDK-tagged |
CNY 5,890.00 |
|
RC202806L4 | Lenti ORF clone of Human chymotrypsinogen B1 (CTRB1), mGFP tagged |
CNY 5,890.00 |
|
RG202806 | CTRB1 (tGFP-tagged) - Human chymotrypsinogen B1 (CTRB1) |
CNY 4,000.00 |
|
SC122612 | CTRB1 (untagged)-Human chymotrypsinogen B1 (CTRB1) |
CNY 2,400.00 |