XPA (NM_000380) Human Tagged Lenti ORF Clone
CAT#: RC204872L1
- LentiORF®
Lenti ORF clone of Human xeroderma pigmentosum, complementation group A (XPA), transcript variant 1, Myc-DDK-tagged
"NM_000380" in other vectors (6)
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CNY 4,800.00
CNY 5,890.00
CNY 600.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | XP1; XPAC |
Vector | pLenti-C-Myc-DDK |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC204872).
|
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_000380 |
ORF Size | 819 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_000380.2 |
RefSeq Size | 1491 bp |
RefSeq ORF | 822 bp |
Locus ID | 7507 |
UniProt ID | P23025 |
Domains | XPA_C |
Protein Families | Druggable Genome |
Protein Pathways | Nucleotide excision repair |
MW | 31.4 kDa |
Gene Summary | This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC204872 | XPA (Myc-DDK-tagged)-Human xeroderma pigmentosum, complementation group A (XPA), transcript variant 1 |
CNY 2,400.00 |
|
RC204872L2 | Lenti ORF clone of Human xeroderma pigmentosum, complementation group A (XPA), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RC204872L3 | Lenti ORF clone of Human xeroderma pigmentosum, complementation group A (XPA), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC204872L4 | Lenti ORF clone of Human xeroderma pigmentosum, complementation group A (XPA), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
RG204872 | XPA (tGFP-tagged) - Human xeroderma pigmentosum, complementation group A (XPA), transcript variant 1 |
CNY 4,000.00 |
|
SC319524 | XPA (untagged)-Human xeroderma pigmentosum, complementation group A (XPA), transcript variant 1 |
CNY 2,400.00 |