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XPA (NM_000380) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC204872L3V
- LentiORF®
-
Lenti ORF particles, XPA (Myc-DDK tagged) - Human xeroderma pigmentosum, complementation group A (XPA), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,170.00
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Specifications
| Product Data | |
| Product Name | XPA (NM_000380) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | XP1; XPAC |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_000380 |
| ORF Size | 819 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC204872).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_000380.2 |
| RefSeq Size | 1491 bp |
| RefSeq ORF | 822 bp |
| Locus ID | 7507 |
| Domains | XPA_C |
| Protein Families | Druggable Genome |
| Protein Pathways | Nucleotide excision repair |
| MW | 31.4 kDa |
| Gene Summary | This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017] |
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