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SLC26A3 (NM_000111) Human Tagged ORF Clone
CAT＃: RC206559
SLC26A3 (Myc-DDK-tagged)-Human solute carrier family 26, member 3 (SLC26A3)
ORF Plasmid: tGFP
"NM_000111" in other vectors (6)
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CNY 5,600.00
CNY 5,800.00
| Cited in 4 publications. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | CLD; DRA |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC206559 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGATTGAACCCTTTGGGAATCAGTATATTGTGGCCAGGCCAGTGTATTCTACAAATGCTTTTGAGGAAA ATCATAAAAAGACAGGAAGACATCATAAGACATTTCTGGATCATCTCAAAGTGTGTTGTAGCTGTTCCCC ACAAAAGGCCAAGAGAATTGTCCTCTCTTTGTTCCCCATAGCATCTTGGTTGCCAGCATACCGGCTTAAA GAATGGTTGCTCAGTGATATTGTTTCTGGTATCAGCACAGGGATTGTGGCCGTACTACAAGGTTTAGCAT TTGCTCTGCTGGTCGACATTCCCCCAGTCTATGGGTTGTATGCATCCTTTTTCCCAGCCATAATCTACCT TTTCTTCGGCACTTCCAGACACATATCCGTGGGTCCGTTTCCGATTCTGAGTATGATGGTGGGACTAGCA GTTTCAGGAGCAGTTTCAAAAGCAGTCCCAGATCGCAATGCAACTACTTTGGGATTGCCTAACAACTCGA ATAATTCTTCACTACTGGATGACGAGAGGGTGAGGGTGGCGGCGGCGGCATCAGTCACAGTGCTTTCTGG AATCATCCAGTTGGCTTTTGGGATTCTGCGGATTGGATTTGTAGTGATATACCTGTCTGAGTCCCTCATC AGTGGCTTCACTACTGCTGCTGCTGTTCATGTTTTGGTTTCCCAACTCAAATTCATTTTTCAGTTGACAG TCCCGTCACACACTGATCCAGTTTCAATTTTCAAAGTACTATACTCTGTATTCTCACAAATAGAGAAGAC TAATATTGCAGACCTGGTGACAGCTCTGATTGTCCTTTTGGTTGTATCCATTGTTAAAGAAATAAATCAG CGCTTCAAAGACAAACTTCCAGTGCCCATTCCAATCGAATTCATTATGACCGTGATTGCAGCAGGTGTAT CCTACGGCTGTGACTTTAAAAACAGGTTTAAAGTGGCTGTGGTTGGGGACATGAATCCTGGATTTCAGCC CCCTATTACACCTGACGTGGAGACTTTCCAAAACACCGTAGGAGATTGCTTCGGCATCGCAATGGTTGCA TTTGCAGTGGCCTTTTCAGTTGCCAGCGTCTATTCCCTCAAATACGATTATCCACTTGATGGCAATCAGG AGTTAATAGCCTTGGGACTGGGTAACATAGTCTGTGGAGTATTCAGAGGATTTGCTGGGAGTACTGCCCT CTCCAGATCAGCAGTTCAGGAGAGCACAGGAGGCAAAACACAGATTGCTGGGCTTATTGGTGCCATCATC GTGCTGATTGTCGTTCTAGCCATTGGATTTCTCCTGGCGCCTCTACAAAAGTCCGTCCTGGCAGCTTTAG CATTGGGAAACTTAAAGGGAATGCTGATGCAGTTTGCTGAAATAGGCAGATTGTGGCGAAAGGACAAATA TGATTGTTTAATTTGGATCATGACCTTCATCTTCACCATTGTCCTGGGACTCGGGTTAGGCCTGGCAGCT AGTGTGGCATTTCAACTGCTAACCATCGTGTTCAGGACCCAATTTCCAAAATGCAGCACGCTGGCTAATA TTGGAAGAACCAACATCTATAAGAATAAAAAAGATTATTATGATATGTATGAGCCAGAAGGAGTGAAAAT TTTCAGATGTCCATCTCCTATCTACTTTGCAAACATTGGTTTCTTTAGGCGGAAACTTATCGATGCTGTT GGCTTTAGTCCACTTCGAATTCTACGCAAGCGCAACAAAGCTTTGAGGAAAATCCGAAAACTGCAGAAGC AAGGCTTGCTACAAGTGACACCAAAAGGATTTATATGTACTGTTGACACCATAAAAGATTCTGACGAAGA GCTGGACAACAATCAGATAGAAGTACTGGACCAGCCAATCAATACCACAGACCTGCCTTTCCACATTGAC TGGAATGATGATCTTCCTCTCAACATTGAGGTCCCCAAAATCAGCCTCCACAGCCTCATTCTCGACTTTT CAGCAGTGTCCTTTCTTGATGTTTCTTCAGTGAGGGGCCTTAAATCGATTTTGCAAGAATTTATCAGGAT CAAGGTAGATGTGTATATCGTTGGAACTGATGATGACTTCATTGAGAAGCTTAACCGGTATGAATTTTTT GATGGTGAAGTGAAAAGCTCAATATTTTTCTTAACAATCCATGATGCTGTTTTGCATATTTTGATGAAGA AAGATTACAGTACTTCAAAGTTTAATCCCAGTCAGGAAAAAGATGGAAAAATTGATTTTACCATAAATAC AAATGGAGGATTACGTAATCGGGTATATGAGGTGCCAGTTGAAACAAAATTC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC206559 protein sequence
Red=Cloning site Green=Tags(s) MIEPFGNQYIVARPVYSTNAFEENHKKTGRHHKTFLDHLKVCCSCSPQKAKRIVLSLFPIASWLPAYRLK EWLLSDIVSGISTGIVAVLQGLAFALLVDIPPVYGLYASFFPAIIYLFFGTSRHISVGPFPILSMMVGLA VSGAVSKAVPDRNATTLGLPNNSNNSSLLDDERVRVAAAASVTVLSGIIQLAFGILRIGFVVIYLSESLI SGFTTAAAVHVLVSQLKFIFQLTVPSHTDPVSIFKVLYSVFSQIEKTNIADLVTALIVLLVVSIVKEINQ RFKDKLPVPIPIEFIMTVIAAGVSYGCDFKNRFKVAVVGDMNPGFQPPITPDVETFQNTVGDCFGIAMVA FAVAFSVASVYSLKYDYPLDGNQELIALGLGNIVCGVFRGFAGSTALSRSAVQESTGGKTQIAGLIGAII VLIVVLAIGFLLAPLQKSVLAALALGNLKGMLMQFAEIGRLWRKDKYDCLIWIMTFIFTIVLGLGLGLAA SVAFQLLTIVFRTQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAV GFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDTIKDSDEELDNNQIEVLDQPINTTDLPFHID WNDDLPLNIEVPKISLHSLILDFSAVSFLDVSSVRGLKSILQEFIRIKVDVYIVGTDDDFIEKLNRYEFF DGEVKSSIFFLTIHDAVLHILMKKDYSTSKFNPSQEKDGKIDFTINTNGGLRNRVYEVPVETKF TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_000111 |
| ORF Size | 2292 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000111.1, NP_000102.1 |
| RefSeq Size | 2894 bp |
| RefSeq ORF | 2295 bp |
| Locus ID | 1811 |
| UniProt ID | P40879 |
| Protein Families | Druggable Genome, Transcription Factors, Transmembrane |
| MW | 84.5 kDa |
| Gene Summary | The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008] |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Adaptation to inflammatory acidity through neutrophil-derived adenosine regulation of SLC26A3
,Cartwright, IM;Curtis, VF;Lanis, JM;Alexeev, EE;Welch, N;Goldberg, MS;Schaefer, REM;Gao, RY;Chun, C;Fennimore, B;Onyiah, JC;Gerich, ME;Dempsey, PJ;Colgan, SP;,
Mucosal Immunol
,PubMed ID 31792360
[SLC26A3]
|
|
Role of N-glycosylation in the expression of human SLC26A2 and A3 anion transport membrane glycoproteins
,Rapp, CL;Li, J;Badior, KE;Williams, DB;Casey, JR;Reithmeier, RAF;,
Biochem. Cell Biol.
,PubMed ID 30462520
[SLC26A3]
|
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SLC26A3 inhibitor identified in small molecule screen blocks colonic fluid absorption and reduces constipation
,Haggie, PM;Cil, O;Lee, S;Tan, JA;Rivera, AA;Phuan, PW;Verkman, AS;,
JCI Insight
,PubMed ID 30046015
[SLC26A3]
|
|
Small-Molecule Inhibitors of Pendrin Potentiate the Diuretic Action of Furosemide
,null,
Journal of the American Society of Nephrology : JASN
,PubMed ID 27153921
[SLC26A3]
|
Documents
| Product Manuals |
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206559L1 | Lenti ORF clone of Human solute carrier family 26, member 3 (SLC26A3), Myc-DDK-tagged |
CNY 8,000.00 |
|
| RC206559L2 | Lenti ORF clone of Human solute carrier family 26, member 3 (SLC26A3), mGFP tagged |
CNY 7,700.00 |
|
| RC206559L3 | Lenti ORF clone of Human solute carrier family 26, member 3 (SLC26A3), Myc-DDK-tagged |
CNY 8,000.00 |
|
| RC206559L4 | Lenti ORF clone of Human solute carrier family 26, member 3 (SLC26A3), mGFP tagged |
CNY 8,000.00 |
|
| RG206559 | SLC26A3 (tGFP-tagged) - Human solute carrier family 26, member 3 (SLC26A3) |
CNY 7,200.00 |
|
| SC122548 | SLC26A3 (untagged)-Human solute carrier family 26, member 3 (SLC26A3) |
CNY 5,600.00 |
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