ACE2 (NM_021804) Human Tagged Lenti ORF Clone (Angiotensin Converting Enzyme 2)
CAT#: RC208442L4
- LentiORF®
Lenti ORF clone of Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2), mGFP tagged
"NM_021804" in other vectors (6)
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CNY 8,296.00
Cited in 5 publications. |
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Synonyms | ACEH |
Vector | pLenti-C-mGFP-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC208442).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_021804 |
ORF Size | 2415 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_021804.1 |
RefSeq Size | 3519 bp |
RefSeq ORF | 2418 bp |
Locus ID | 59272 |
UniProt ID | Q9BYF1 |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
Protein Pathways | Renin-angiotensin system |
MW | 92.5 kDa |
Gene Summary | The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. ACE2 is known to be expressed in various human organs, and its organ- and cell-specific expression suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronavirus HCoV-NL63 and the human severe acute respiratory syndrome coronaviruses, SARS-CoV and SARS-CoV-2, the latter is the causative agent of coronavirus disease-2019 (COVID-19). Multiple splice variants have been found for this gene and the dACE2 (or MIRb-ACE2) splice variant has been found to be interferon inducible. [provided by RefSeq, Nov 2020] |
Citations (5)
The use of this cDNA Clones has been cited in the following citations: |
---|
Carboxymethyl chitosan/sodium alginate hydrogels with polydopamine coatings as promising dressings for eliminating biofilm and multidrug-resistant bacteria induced wound healing.
,null,
International journal of biological macromolecules
,PubMed ID 36427613
[ACE2]
|
Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy
,null,
Immunity
,PubMed ID 34453881
[ACE2]
|
Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers, and convalescent plasma donors
,null,
JCI Insight
,PubMed ID 33035201
[ACE2]
|
Cross-Sectional Evaluation of Humoral Responses against SARS-CoV-2 Spike
,null,
Cell Reports Medicine
,PubMed ID 33015650
[ACE2]
|
Cross-sectional evaluation of humoral responses against SARS-CoV-2 Spike
,Prévost, J;Gasser, R;Beaudoin-Bussières, G;Richard, J;Duerr, R;Laumaea, A;Anand, SP;Goyette, G;Ding, S;Medjahed, H;Lewin, A;Perreault, J;Tremblay, T;Gendron-Lepage, G;Gauthier, N;Carrier, M;Marcoux, D;Piché, A;Lavoie, M;Benoit, A;Loungnarath, V;Brochu, G;Desforges, M;Talbot, PJ;Gould Maule, GT;Côté, M;Therrien, C;Serhir, B;Bazin, R;Roger, M;Finzi, A;,
bioRxiv : the preprint server for biology
,PubMed ID 32577637
[ACE2]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC208442 | ACE2 (Myc-DDK-tagged)-Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2) |
CNY 5,896.00 |
|
RC208442L1 | Lenti ORF clone of Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2), Myc-DDK-tagged |
CNY 8,296.00 |
|
RC208442L2 | Lenti ORF clone of Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2), mGFP tagged |
CNY 8,296.00 |
|
RC208442L3 | Lenti ORF clone of Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2), Myc-DDK-tagged |
CNY 8,296.00 |
|
RG208442 | ACE2 (tGFP-tagged) - Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2) |
CNY 7,496.00 |
|
SC124099 | ACE2 (untagged)-Human angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2) |
CNY 8,856.00 |
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