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Hairless (HR) (NM_005144) Human Tagged ORF Clone
CAT＃: RC209010
HR (Myc-DDK-tagged)-Human hairless homolog (mouse) (HR), transcript variant 1
ORF Plasmid: tGFP
"NM_005144" in other vectors (4)
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CNY 8,280.00
Product images
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | ALUNC; AU; HSA277165; HYPT4; MUHH; MUHH1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC209010 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGAGTACGCCCAGCTTCCTGAAGGGCACCCCAACCTGGGAGAAGACGGCCCCAGAGAACGGCATCG TGAGACAGGAGCCCGGCAGCCCGCCTCGAGATGGACTGCACCATGGGCCGCTGTGCCTGGGAGAGCCTGC TCCCTTTTGGAGGGGCGTCCTGAGCACCCCAGACTCCTGGCTTCCCCCTGGCTTCCCCCAGGGCCCCAAG GACATGCTCCCACTTGTGGAGGGCGAGGGCCCCCAGAATGGGGAGAGGAAGGTCAACTGGCTGGGCAGCA AAGAGGGACTGCGCTGGAAGGAGGCCATGCTTACCCATCCGCTGGCATTCTGCGGGCCAGCGTGCCCACC TCGCTGTGGCCCCCTGATGCCTGAGCATAGTGGTGGCCATCTCAAGAGTGACCCTGTGGCCTTCCGGCCC TGGCACTGCCCTTTCCTTCTGGAGACCAAGATCCTGGAGCGAGCTCCCTTCTGGGTGCCCACCTGCTTGC CACCCTACCTAGTGTCTGGCCTGCCCCCAGAGCATCCATGTGACTGGCCCCTGACCCCGCACCCCTGGGT ATACTCCGGGGGCCAGCCCAAAGTGCCCTCTGCCTTCAGCTTAGGCAGCAAGGGCTTTTACTACAAGGAT CCGAGCATTCCCAGGTTGGCAAAGGAGCCCTTGGCAGCTGCGGAACCTGGGTTGTTTGGCTTAAACTCTG GTGGGCACCTGCAGAGAGCCGGGGAGGCCGAACGCCCTTCACTGCACCAGAGGGATGGAGAGATGGGAGC TGGCCGGCAGCAGAATCCTTGCCCGCTCTTCCTGGGGCAGCCAGACACTGTGCCCTGGACCTCCTGGCCC GCTTGTCCCCCAGGCCTTGTTCATACTCTTGGCAACGTCTGGGCTGGGCCAGGCGATGGGAACCTTGGGT ACCAGCTGGGGCCACCAGCAACACCAAGGTGCCCCTCTCCTGAGCCGCCTGTCACCCAGCGGGGCTGCTG TTCATCCTACCCACCCACTAAAGGTGGGGGTCTTGGCCCTTGTGGGAAGTGCCAGGAGGGCCTGGAGGGG GGTGCCAGTGGAGCCAGCGAACCCAGCGAGGAAGTGAACAAGGCCTCTGGCCCCAGGGCCTGTCCCCCCA GCCACCACACCAAGCTGAAGAAGACATGGCTCACACGGCACTCGGAGCAGTTTGAATGTCCACGCGGCTG CCCTGAGGTCGAGGAGAGGCCGGTTGCTCGGCTCCGGGCCCTCAAAAGGGCAGGCAGCCCCGAGGTCCAG GGAGCAATGGGCAGTCCAGCCCCCAAGCGGCCACCGGACCCTTTCCCAGGCACTGCAGAACAGGGGGCTG GGGGTTGGCAGGAGGTGCGGGACACATCGATAGGGAACAAGGATGTGGACTCGGGACAGCATGATGAGCA GAAAGGACCCCAAGATGGCCAGGCCAGTCTCCAGGACCCGGGACTTCAGGACATACCATGCCTGGCTCTC CCTGCAAAACTGGCTCAATGCCAAAGTTGTGCCCAGGCAGCTGGAGAGGGAGGAGGGCACGCCTGCCACT CTCAGCAAGTGCGGAGATCGCCTCTGGGAGGGGAGCTGCAGCAGGAGGAAGACACAGCCACCAACTCCAG CTCTGAGGAAGGCCCAGGGTCCGGCCCTGACAGCCGGCTCAGCACAGGCCTCGCCAAGCACCTGCTCAGT GGTTTGGGGGACCGACTGTGCCGCCTGCTGCGGAGGGAGCGGGAGGCCCTGGCTTGGGCCCAGCGGGAAG GCCAAGGGCCAGCCGTGACAGAGGACAGCCCAGGCATTCCACGCTGCTGCAGCCGTTGCCACCATGGACT CTTCAACACCCACTGGCGATGTCCCCGCTGCAGCCACCGGCTGTGTGTGGCCTGTGGTCGTGTGGCAGGC ACTGGGCGGGCCAGGGAGAAAGCAGGCTTTCAGGAGCAGTCCGCGGAGGAGTGCACGCAGGAGGCCGGGC ACGCTGCCTGTTCCCTGATGCTGACCCAGTTTGTCTCCAGCCAGGCTTTGGCAGAGCTGAGCACTGCAAT GCACCAGGTCTGGGTCAAGTTTGATATCCGGGGGCACTGCCCCTGCCAAGCTGATGCCCGGGTATGGGCC CCCGGGGATGCAGGCCAGCAGAAGGAATCAACACAGAAAACGCCCCCAACTCCACAACCTTCCTGCAATG GCGACACCCACAGGACCAAGAGCATCAAAGAGGAGACCCCCGATTCCGCTGAGACCCCAGCAGAGGACCG TGCTGGCCGAGGGCCCCTGCCTTGTCCTTCTCTCTGCGAACTGCTGGCTTCTACCGCGGTCAAACTCTGC TTGGGCCATGAGCGAATACACATGGCCTTCGCCCCCGTCACTCCGGCCCTGCCCAGTGATGACCGCATCA CCAACATCCTGGACAGCATTATCGCACAGGTGGTGGAACGGAAGATCCAGGAGAAAGCCCTGGGGCCGGG GCTTCGAGCTGGCCCGGGTCTGCGCAAGGGCCTGGGCCTGCCCCTCTCTCCAGTGCGGCCCCGGCTGCCT CCCCCAGGGGCTTTGCTGTGGCTGCAGGAGCCCCAGCCTTGCCCTCGGCGTGGCTTCCACCTCTTCCAGG AGCACTGGAGGCAGGGCCAGCCTGTGTTGGTGTCAGGGATCCAAAGGACATTGCAGGGCAACCTGTGGGG GACAGAAGCTCTTGGGGCACTTGGAGGCCAGGTGCAGGCGCTGAGCCCCCTCGGACCTCCCCAGCCCAGC AGCCTGGGCAGCACAACATTCTGGGAGGGCTTCTCCTGGCCTGAGCTTCGCCCAAAGTCAGACGAGGGCT CTGTCCTCCTGCTGCACCGAGCTTTGGGGGATGAGGACACCAGCAGGGTGGAGAACCTAGCTGCCAGTCT GCCACTTCCGGAGTACTGCGCCCTCCATGGAAAACTCAACCTGGCTTCCTACCTCCCACCGGGCCTTGCC CTGCGTCCACTGGAGCCCCAGCTCTGGGCAGCCTATGGTGTGAGCCCGCACCGGGGACACCTGGGGACCA AGAACCTCTGTGTGGAGGTGGCCGACCTGGTCAGCATCCTGGTGCATGCCGACACACCACTGCCTGCCTG GCACCGGGCACAGAAAGACTTCCTTTCAGGCCTGGACGGGGAGGGGCTCTGGTCTCCGGGCAGCCAGGTC AGCACTGTGTGGCACGTGTTCCGGGCACAGGACGCCCAGCGCATCCGCCGCTTTCTCCAGATGGTGTGCC CGGCCGGGGCAGGCGCCCTGGAGCCTGGCGCCCCAGGCAGCTGCTACCTGGATGCAGGGCTGCGGCGGCG CCTGCGGGAGGAGTGGGGCGTGAGCTGCTGGACCCTGCTCCAGGCCCCCGGAGAGGCCGTGCTGGTGCCT GCAGGGGCTCCCCACCAGGTGCAGGGCCTGGTGAGCACAGTCAGCGTCACTCAGCACTTCCTCTCCCCTG AGACCTCTGCCCTCTCTGCTCAGCTCTGCCACCAGGGACCCAGCCTTCCCCCTGACTGCCACCTGCTTTA TGCCCAGATGGACTGGGCTGTGTTCCAAGCAGTGAAGGTGGCCGTGGGGACATTACAGGAGGCCAAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC209010 protein sequence
Red=Cloning site Green=Tags(s) MESTPSFLKGTPTWEKTAPENGIVRQEPGSPPRDGLHHGPLCLGEPAPFWRGVLSTPDSWLPPGFPQGPK DMLPLVEGEGPQNGERKVNWLGSKEGLRWKEAMLTHPLAFCGPACPPRCGPLMPEHSGGHLKSDPVAFRP WHCPFLLETKILERAPFWVPTCLPPYLVSGLPPEHPCDWPLTPHPWVYSGGQPKVPSAFSLGSKGFYYKD PSIPRLAKEPLAAAEPGLFGLNSGGHLQRAGEAERPSLHQRDGEMGAGRQQNPCPLFLGQPDTVPWTSWP ACPPGLVHTLGNVWAGPGDGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEG GASGASEPSEEVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSPEVQ GAMGSPAPKRPPDPFPGTAEQGAGGWQEVRDTSIGNKDVDSGQHDEQKGPQDGQASLQDPGLQDIPCLAL PAKLAQCQSCAQAAGEGGGHACHSQQVRRSPLGGELQQEEDTATNSSSEEGPGSGPDSRLSTGLAKHLLS GLGDRLCRLLRREREALAWAQREGQGPAVTEDSPGIPRCCSRCHHGLFNTHWRCPRCSHRLCVACGRVAG TGRAREKAGFQEQSAEECTQEAGHAACSLMLTQFVSSQALAELSTAMHQVWVKFDIRGHCPCQADARVWA PGDAGQQKESTQKTPPTPQPSCNGDTHRTKSIKEETPDSAETPAEDRAGRGPLPCPSLCELLASTAVKLC LGHERIHMAFAPVTPALPSDDRITNILDSIIAQVVERKIQEKALGPGLRAGPGLRKGLGLPLSPVRPRLP PPGALLWLQEPQPCPRRGFHLFQEHWRQGQPVLVSGIQRTLQGNLWGTEALGALGGQVQALSPLGPPQPS SLGSTTFWEGFSWPELRPKSDEGSVLLLHRALGDEDTSRVENLAASLPLPEYCALHGKLNLASYLPPGLA LRPLEPQLWAAYGVSPHRGHLGTKNLCVEVADLVSILVHADTPLPAWHRAQKDFLSGLDGEGLWSPGSQV STVWHVFRAQDAQRIRRFLQMVCPAGAGALEPGAPGSCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVP AGAPHQVQGLVSTVSVTQHFLSPETSALSAQLCHQGPSLPPDCHLLYAQMDWAVFQAVKVAVGTLQEAK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_005144 |
| ORF Size | 3567 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_005144.5 |
| RefSeq Size | 5528 bp |
| RefSeq ORF | 3570 bp |
| Locus ID | 55806 |
| UniProt ID | O43593 |
| Protein Families | Druggable Genome, Transcription Factors |
| MW | 127.5 kDa |
| Gene Summary | This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209010L3 | Lenti ORF clone of Human hairless homolog (mouse) (HR), transcript variant 1, Myc-DDK-tagged |
CNY 11,500.00 |
|
| RC209010L4 | Lenti ORF clone of Human hairless homolog (mouse) (HR), transcript variant 1, mGFP tagged |
CNY 11,500.00 |
|
| RG209010 | HR (tGFP-tagged) - Human hairless homolog (mouse) (HR), transcript variant 1 |
CNY 10,550.00 |
|
| SC303591 | HR (untagged)-Human hairless homolog (mouse) (HR), transcript variant 1 |
CNY 8,288.00 |
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