SOCS5 (NM_014011) Human Tagged ORF Clone
CAT#: RC214950
SOCS5 (Myc-DDK-tagged)-Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1
ORF Plasmid: tGFP
"NM_014011" in other vectors (6)
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CNY 5,984.00
CNY 300.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Synonyms | CIS6; Cish5; CISH6; SOCS-5 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RC214950 representing NM_014011
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGATAAAGTGGGAAAAATGTGGAATAACTTCAAATACAGGTGTCAGAATCTCTTCGGTCATGAGGGAG GAAGCCGTAGTGAAAATGTGGACATGAACTCCAACAGATGTTTGTCTGTCAAAGAGAAAAACATCAGCAT AGGAGACTCAACTCCTCAGCAACAAAGCAGTCCCTTAAGAGAAAATATTGCCTTACAACTGGGATTAAGC CCTTCGAAGAATTCTTCAAGGAGAAATCAAAATTGTGCCACAGAAATCCCTCAAATTGTTGAAATAAGCA TCGAAAAGGATAATGATTCTTGTGTTACCCCAGGAACAAGACTTGCACGAAGAGATTCCTACTCTCGACA TGCTCCATGGGGTGGGAAGAAAAAACATTCCTGTTCTACAAAGACCCAGAGTTCATTGGATGCTGATAAA AAGTTTGGTAGAACTCGAAGTGGACTTCAAAGGAGAGAGAGGCGCTACGGCGTAAGTTCTGTACACGACA TGGACAGTGTTTCCAGCAGAACTGTAGGAAGTCGCTCTCTAAGACAGAGGTTGCAGGATACTGTGGGCTT GTGTTTTCCCATGAGAACTTACAGCAAGCAGTCAAAGCCTCTCTTTTCCAATAAAAGAAAAATCCATCTC TCTGAATTAATGCTTGAGAAATGCCCTTTTCCTGCTGGCTCAGATTTAGCCCAAAAATGGCATTTGATTA AACAGCATACAGCTCCTGTGAGCCCACATTCAACATTTTTTGATACATTTGATCCATCTTTGGTTTCTAC AGAAGATGAAGAAGATAGGCTTAGAGAGAGAAGGCGGCTTAGTATTGAAGAAGGGGTTGATCCCCCTCCC AATGCACAAATACATACATTTGAAGCTACTGCACAGGTTAATCCATTATATAAACTGGGACCAAAATTAG CTCCTGGAATGACTGAAATAAGTGGGGACAGTTCTGCAATTCCACAAGCTAATTGTGACTCGGAAGAGGA TACAACCACCCTGTGTTTGCAGTCACGGAGGCAGAAGCAGCGTCAGATATCTGGAGACAGCCATACGCAT GTTAGCAGACAGGGAGCTTGGAAAGTCCACACACAGATTGATTACATACACTGCCTCGTGCCTGATTTGC TTCAAATTACAGGGAATCCCTGTTACTGGGGAGTGATGGACCGTTATGAAGCAGAAGCCCTTCTCGAAGG GAAACCTGAAGGCACGTTTTTGCTCAGGGACTCTGCGCAAGAGGACTACCTCTTCTCTGTGAGCTTCCGC CGCTACAACAGATCCCTGCATGCCCGAATTGAGCAGTGGAATCACAACTTTAGTTTCGACGCCCATGACC CGTGTGTATTTCACTCCTCCACTGTAACGGGACTTTTAGAACATTATAAAGATCCCAGTTCGTGCATGTT TTTTGAACCATTGCTTACTATATCACTAAATAGGACTTTCCCTTTTAGCCTGCAGTATATCTGTCGCGCG GTAATCTGCAGGTGCACTACGTATGATGGAATTGATGGGCTCCCTCTACCCTCAATGTTACAGGATTTTT TAAAAGAGTATCATTATAAACAAAAAGTTAGAGTTCGCTGGTTGGAACGAGAACCAGTCAAGGCAAAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC214950 representing NM_014011
Red=Cloning site Green=Tags(s) MDKVGKMWNNFKYRCQNLFGHEGGSRSENVDMNSNRCLSVKEKNISIGDSTPQQQSSPLRENIALQLGLS PSKNSSRRNQNCATEIPQIVEISIEKDNDSCVTPGTRLARRDSYSRHAPWGGKKKHSCSTKTQSSLDADK KFGRTRSGLQRRERRYGVSSVHDMDSVSSRTVGSRSLRQRLQDTVGLCFPMRTYSKQSKPLFSNKRKIHL SELMLEKCPFPAGSDLAQKWHLIKQHTAPVSPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPP NAQIHTFEATAQVNPLYKLGPKLAPGMTEISGDSSAIPQANCDSEEDTTTLCLQSRRQKQRQISGDSHTH VSRQGAWKVHTQIDYIHCLVPDLLQITGNPCYWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFR RYNRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGLLEHYKDPSSCMFFEPLLTISLNRTFPFSLQYICRA VICRCTTYDGIDGLPLPSMLQDFLKEYHYKQKVRVRWLEREPVKAK TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Chromatograms |
CHROMATOGRAMS
Sequencher program is needed, download here. |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_014011 |
ORF Size | 1608 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_014011.4, NP_054730.1 |
RefSeq Size | 4422 bp |
RefSeq ORF | 1611 bp |
Locus ID | 9655 |
UniProt ID | O75159 |
Domains | SH2, SOCS |
Protein Families | Druggable Genome |
Protein Pathways | Jak-STAT signaling pathway |
MW | 61.1 kDa |
Gene Summary | The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC214950L1 | Lenti ORF clone of Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1, Myc-DDK-tagged |
CNY 8,384.00 |
|
RC214950L2 | Lenti ORF clone of Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1, mGFP tagged |
CNY 8,384.00 |
|
RC214950L3 | Lenti ORF clone of Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC214950L4 | Lenti ORF clone of Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RG214950 | SOCS5 (tGFP-tagged) - Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1 |
CNY 7,584.00 |
|
SC110087 | SOCS5 (untagged)-Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1 |
CNY 6,000.00 |