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SOCS5 (NM_014011) Human Untagged Clone
CAT＃: SC110087
SOCS5 (untagged)-Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1
CNY 6,000.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CIS6; Cish5; CISH6; SOCS-5 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC110087 sequence for NM_014011 edited (data generated by NextGen Sequencing)
ATGGATAAAGTGGGAAAAATGTGGAATAACTTCAAATACAGGTGTCAGAATCTCTTCGGT CATGAGGGAGGAAGCCGTAGTGAAAATGTGGACATGAACTCCAACAGATGTTTGTCTGTC AAAGAGAAAAACATCAGCATAGGAGACTCAACTCCTCAGCAACAAAGCAGTCCCTTAAGA GAAAATATTGCCTTACAACTGGGATTAAGCCCTTCGAAGAATTCTTCAAGGAGAAATCAA AATTGTGCCACAGAAATCCCTCAAATTGTTGAAATAAGCATCGAAAAGGATAATGATTCT TGTGTTACCCCAGGAACAAGACTTGCACGAAGAGATTCCTACTCTCGACATGCTCCATGG GGTGGGAAGAAAAAACATTCCTGTTCTACAAAGACCCAGAGTTCATTGGATGCTGATAAA AAGTTTGGTAGAACTCGAAGTGGACTTCAAAGGAGAGAGAGGCGCTACGGCGTAAGTTCT GTACACGACATGGACAGTGTTTCCAGCAGAACTGTAGGAAGTCGCTCTCTAAGACAGAGG TTGCAGGATACTGTGGGCTTGTGTTTTCCCATGAGAACTTACAGCAAGCAGTCAAAGCCT CTCTTTTCCAATAAAAGAAAAATCCATCTCTCTGAATTAATGCTTGAGAAATGCCCTTTT CCTGCTGGCTCAGATTTAGCCCAAAAATGGCATTTGATTAAACAGCATACAGCTCCTGTG AGCCCACATTCAACATTTTTTGATACATTTGATCCATCTTTGGTTTCTACAGAAGATGAA GAAGATAGGCTTAGAGAGAGAAGGCGGCTTAGTATTGAAGAAGGGGTTGATCCCCCTCCC AATGCACAAATACATACATTTGAAGCTACTGCACAGGTTAATCCATTATATAAACTGGGA CCAAAATTAGCTCCTGGAATGACTGAAATAAGTGGGGACAGTTCTGCAATTCCACAAGCT AATTGTGACTCGGAAGAGGATACAACCACCCTGTGTTTGCAGTCACGGAGGCAGAAGCAG CGTCAGATATCTGGAGACAGCCATACGCATGTTAGCAGACAGGGAGCTTGGAAAGTCCAC ACACAGATTGATTACATACACTGCCTCGTGCCTGATTTGCTTCAAATTACAGGGAATCCC TGTTACTGGGGAGTGATGGACCGTTATGAAGCAGAAGCCCTTCTCGAAGGGAAACCTGAA GGCACGTTTTTGCTCAGGGACTCTGCGCAAGAGGACTACCTCTTCTCTGTGAGCTTCCGC CGCTACAACAGATCCCTGCATGCCCGAATTGAGCAGTGGAATCACAACTTTAGTTTCGAC GCCCATGACCCGTGTGTATTTCACTCCTCCACTGTAACGGGACTTTTAGAACATTATAAA GATCCCAGTTCGTGCATGTTTTTTGAACCATTGCTTACTATATCACTAAATAGGACTTTC CCTTTTAGCCTGCAGTATATCTGTCGCGCGGTAATCTGCAGGTGCACTACGTATGATGGA ATTGATGGGCTCCCTCTACCCTCAATGTTACAGGATTTTTTAAAAGAGTATCATTATAAA CAAAAAGTTAGAGTTCGCTGGTTGGAACGAGAACCAGTCAAGGCAAAGTAA Clone variation with respect to NM_014011.4 1047 c=>g >OriGene 5' read for NM_014011 unedited
NGTTCAGATTTGTATACGATGACTATAGGCGGCCCGCGAATTCGCACGAGGCCTCGTGCC GAATTCGGCACGAGGGACGCACCGGAGGGCAGGCGGACTCGCCCTGTCGGTGACTGCGCC GTCCGGGCCCGTCCTGCCTGGCCGCAGGTGCCCTGGATGAGGCCGCCCCGCGCGCCCCAA ACGATTTTATAATCAATGGATAAAGTGTGTTATATGTGGAATAACTTCAAATACAGGTGT CAGAATCTCTTCGGTCATGAGGGAGGAAGCCGTAGTGAAAATGTGGACATGAACTCCAAC AGATGTTTGTCTGTCAAAGAGAAAAACATCAGCATAGGAGACTCAACTCCTCAGCAACAA AGCAGTCCCTTAAGAGAAAATATTGCCTTACAACTGGGATTAAGCCCTTCGAAGAATTCT TCAAGGAGAAATCAAAATTGTGCCACAGAAATCCCTCAAATTGTTGAAATAAGCATCGAA AAGGATAATGATTCTTGTGTTACCCCAGGAACAAGACTTGCACGAAGAGATTCCTACTCT CGACATGCTCCATGGGGTGGGAAGAAAAAACATTCCTGTTCTACAAAGACCCAGAGTTCA TTGGATGCTGATAAAAAGTTTGATAGAACTCGAAGTGGACTTCAAAGGAGAGAGACGCGC TACCGCGTAAGTTCTGTACACGACATGGACAGTGTTTCCCGCAGAACTGTANGAAGTCGC TCTCTAACACAGAGTTGCACGATACCGCGGGCTTGCGCTTCTCCACTGAGACTTACAGAA GCAGTCACAAGCCTTCTTTTTCAATAAAAGAAAACCCTCTCTCTGAATTAAGCTTGAAAA AGCCCCTATACTGCTGGCTTAAATTAGCCCAAAATGGCCTTTGGTTAAACACATACCGCT CC >OriGene 3' read for NM_014011 unedited
NNNNTTTAGCTTTGAACCGGCGGCCGCATNCTAAGATCGAGTTTTTTTTTTTTTTTTTTG CAAGTTCATGCTGGTGATTTTTCTTTTTTAAAAGTAAGCCACTAATATTTTAAGACAAAA ATTTAAACCAAAAATTGCATATTAATATTATACACAAACTGAAACATGTGACTTTTAGCA CAGTGTATACATGCTTACATAAACTCAAACACATTTAAAACAATTTCCATTTAACATATG AAAGTTTTGAAATACATAAAAGCATTAATACTTTCTATAAAACTACAGTTAGAACATCAA TTTGCTACAAGCATATAAAAACATCAAGTGCTTTCTTGGAGTTTCAAGTTTCCTCTCTAA AACACAATCTTGCTCACATATATAGTCCTTTTCCAATAATCAGTATGAACTTTTCTTTTT CTCAAGAGGTTTATTTTCCAGGTACATTATAAGCTCAAGAAAAAAGACCCAACAATTAGG CAATATAATTATGTCATAACAACTTAATTGCACATAATGCTTTAAAGTAGGTTTGGATGA AGTTCTCAAACACTTTGGTATATGATCTTCAGGGACTTTAATTAGAAACAACAGAAATTA AAAGTCCCTTCAATCCCCATTTTGCTTTAAAAGGGACAAGTCTTTGGTTAAAGTTCTACA TTTTGGGCATTTATTTTTAATTAAGATGGTCCCCAAACCAATAAATGGTACTGATCTATT ACAAATTCACAAGACTTCATTTAACCTGCTTCTGATGCAGTGGGAGGTTACAGATACTCA TTTACTATAATATGTCATTGGATAGTTTCAATCTTTCATTTATAAGCAGAGAAATCAATA NGGTTATTACTTCTCTGTCAGTTTTCTGTTATAACCTAAACTGTACANGTATTTGCAGTA ACTACC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014011 |
| Insert Size | 4760 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_014011.4, NP_054730.1 |
| RefSeq Size | 4422 bp |
| RefSeq ORF | 1611 bp |
| Locus ID | 9655 |
| UniProt ID | O75159 |
| Domains | SH2, SOCS |
| Protein Families | Druggable Genome |
| Protein Pathways | Jak-STAT signaling pathway |
| Gene Summary | The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. Both variants encode the same protein. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC214950 | SOCS5 (Myc-DDK-tagged)-Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1 |
CNY 5,984.00 |
|
| RC214950L1 | Lenti ORF clone of Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1, Myc-DDK-tagged |
CNY 8,384.00 |
|
| RC214950L2 | Lenti ORF clone of Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1, mGFP tagged |
CNY 8,384.00 |
|
| RC214950L3 | Lenti ORF clone of Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC214950L4 | Lenti ORF clone of Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG214950 | SOCS5 (tGFP-tagged) - Human suppressor of cytokine signaling 5 (SOCS5), transcript variant 1 |
CNY 7,584.00 |
