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C14orf151 (INF2) (NM_022489) Human Tagged ORF Clone
CAT＃: RC216716
- TrueORF®
INF2 (Myc-DDK-tagged)-Human inverted formin, FH2 and WH2 domain containing (INF2), transcript variant 1
ORF Plasmid: tGFP
"NM_022489" in other vectors (4)
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CNY 13,040.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | C14orf151; C14orf173; CMTDIE; FSGS5; pp9484 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_022489 |
| ORF Size | 3747 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022489.3, NP_071934.3 |
| RefSeq Size | 4725 bp |
| RefSeq ORF | 3750 bp |
| Locus ID | 64423 |
| UniProt ID | Q27J81 |
| Domains | WH2 |
| Protein Families | Druggable Genome |
| MW | 135.4 kDa |
| Gene Summary | This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.[provided by RefSeq, Aug 2010] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Inverted Formin 2 Regulates Actin Dynamics by Antagonizing Rho/Diaphanous-related Formin Signaling
,Hua Sun, Johannes Schlondorff, Henry N. Higgs, and Martin R. Pollak,
J. Am. Soc. Nephrol., May 2013; 24: 917 - 929.
,PubMed ID 23620398
[INF2]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216716L3 | Lenti-ORF clone of INF2 (Myc-DDK-tagged)-Human inverted formin, FH2 and WH2 domain containing (INF2), transcript variant 1 |
CNY 14,350.00 |
|
| RC216716L4 | Lenti-ORF clone of INF2 (mGFP-tagged)-Human inverted formin, FH2 and WH2 domain containing (INF2), transcript variant 1 |
CNY 14,350.00 |
|
| RG216716 | INF2 (tGFP-tagged) - Human inverted formin, FH2 and WH2 domain containing (INF2), transcript variant 1 |
CNY 13,680.00 |
|
| SC318567 | INF2 (untagged)-Human inverted formin, FH2 and WH2 domain containing (INF2), transcript variant 1 |
CNY 24,040.00 |
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