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C14orf151 (INF2) (NM_022489) Human Untagged Clone
CAT＃: SC318567
INF2 (untagged)-Human inverted formin, FH2 and WH2 domain containing (INF2), transcript variant 1
"NM_022489" in other vectors (4)
CNY 24,040.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C14orf151; C14orf173; CMTDIE; FSGS5; pp9484 |
| Vector | pCMV6 series |
| Sequence Data |
>NCBI ORF sequence for NM_022489, the custom clone sequence may differ by one or more nucleotides
ATGTCGGTGAAGGAGGGCGCACAGCGCAAGTGGGCAGCGCTGAAGGAGAAGCTGGGGCCA CAGGATTCGGACCCCACGGAGGCCAACCTGGAGAGCGCGGACCCCGAGCTGTGCATCCGG CTGCTCCAGATGCCCTCTGTGGTCAACTACTCCGGCCTGCGCAAGCGCCTGGAGGGCAGC GACGGCGGCTGGATGGTGCAGTTCCTGGAGCAGAGCGGCCTGGACCTGCTGCTGGAGGCG CTGGCGCGGCTGTCGGGCCGCGGCGTTGCACGTATCTCCGACGCCCTGCTGCAGCTCACC TGCGTCAGCTGCGTGCGCGCCGTCATGAACTCGCGGCAGGGCATCGAGTACATCCTCAGC AACCAGGGCTACGTGCGCCAGCTCTCCCAGGCCCTGGACACATCCAACGTGATGGTGAAG AAGCAGGTGTTTGAGCTACTGGCTGCCCTGTGCATCTACTCTCCCGAGGGCCACGTGCTG ACCCTGGACGCCCTGGACCACTACAAGACGGTGTGCAGCCAGCAGTACCGCTTCAGCATT GTCATGAACGAGCTCTCCGGCAGCGACAACGTGCCCTACGTGGTCACCCTGCTTAGCGTG ATCAACGCCGTCATCTTGGGCCCCGAGGACCTGCGCGCGCGCACCCAGCTGCGGAACGAG TTTATCGGGCTGCAGCTGCTGGACGTCCTGGCTCGCCTGCGAGACCTGGAGGATGCCGAC CTGCTGATCCAGCTGGAGGCTTTCGAGGAGGCTAAGGCCGAGGACGAGGAGGAGCTGCTG CGAGTCTCTGGCGGGGTCGACATGAGCAGCCACCAGGAGGTCTTTGCCTCCCTGTTCCAC AAGGTGAGCTGCTCCCCGGTGTCTGCCCAGCTCCTGTCGGTGCTGCAGGGCCTCCTGCAC CTGGAGCCCACCCTCCGCTCCAGCCAGCTGCTCTGGGAGGCCCTGGAGAGCCTCGTGAAC CGGGCCGTGCTCCTGGCCAGCGATGCCCAGGAATGCACCCTGGAGGAAGTGGTTGAGCGG CTCCTGTCTGTCAAGGGGCGACCCAGACCGAGCCCCCTGGTCAAGGCCCATAAAAGCGTC CAGGCCAACCTAGACCAGAGCCAGAGGGGCAGCTCCCCGCAAAACACTACAACCCCCAAG CCCAGCGTGGAGGGCCAGCAGCCAGCAGCAGCTGCTGCCTGCGAGCCCGTGGACCACGCC CAGAGTGAGAGCATCCTGAAAGTTTCGCAGCCCAGAGCCCTGGAGCAGCAGGCGTCCACC CCACCCCCACCCCCACCCCCACCCCTGCTCCCTGGTTCCAGTGCCGAGCCCCCTCCCCCT CCCCCACCACCCCCCCTGCCCAGTGTGGGGGCTAAGGCCCTCCCAACAGCACCCCCGCCC CCACCCCTGCCAGGCCTGGGGGCCATGGCCCCCCCAGCACCTCCTCTACCACCACCCCTG CCAGGCTCCTGTGAGTTCCTGCCCCCACCACCTCCACCACTCCCGGGCTTGGGATGCCCG CCCCCACCCCCACCCCTGCTGCCTGGTATGGGCTGGGGCCCTCCTCCACCCCCACCTCCA CTACTGCCCTGCACCTGCAGCCCCCCCGTGGCGGGAGGCATGGAGGAGGTCATCGTGGCC CAGGTGGACCATGGCTTGGGCTCAGCATGGGTCCCCAGCCATCGGCGGGTGAACCCACCC ACACTGCGCATGAAGAAGCTGAACTGGCAGAAGCTGCCATCCAACGTGGCACGTGAGCAC AACTCTATGTGGGCGTCCCTGAGCAGCCCCGACGCCGAGGCTGTGGAGCCCGACTTCTCC AGCATCGAGCGACTATTCTCCTTCCCTGCAGCCAAGCCCAAGGAGCCCACCATGGTGGCC CCCCGGGCCAGGAAGGAGCCCAAGGAGATCACTTTCCTCGATGCCAAGAAGAGCCTGAAC CTCAACATCTTCCTGAAGCAATTTAAGTGCTCCAACGAGGAGGTCGCTGCTATGATCCGG GCTGGAGATACCACCAAGTTTGATGTGGAGGTTCTCAAACAACTCCTTAAGCTCCTTCCC GAGAAGCACGAGATTGAAAACCTGCGGGCATTCACAGAGGAGCGAGCCAAGCTGGCCAGC GCCGACCACTTCTACCTCCTCCTGCTGGCCATTCCCTGCTACCAGCTGCGAATCGAGTGC ATGCTGCTGTGTGAGGGCGCGGCCGCCGTGCTGGACATGGTGCGGCCCAAGGCCCAGCTG GTGCTGGCTGCCTGCGAAAGCCTGCTCACCAGCCGCCAGCTGCCCATCTTCTGCCAGCTG ATCCTGAGAATTGGGAACTTCCTCAACTACGGCAGCCACACCGGTGACGCCGACGGCTTC AAGATCAGCACATTGCTGAAGCTCACGGAGACCAAGTCCCAGCAGAACCGCGTGACGCTG CTGCACCACGTGCTGGAGGAAGCGGAAAAGAGCCACCCCGACCTCCTGCAGCTGCCCCGG GACCTGGAACAGCCCTCGCAAGCAGCAGGGATCAACCTGGAGATCATCCGCTCAGAGGCC AGCTCCAACCTGAAGAAGCTTCTGGAGACCGAGCGGAAGGTGTCTGCCTCCGTGGCCGAG GTCCAGGAGCAGTACACCGAGCGCCTCCAGGCCAGCATCTCGGCCTTCCGGGCACTGGAT GAGCTGTTTGAGGCCATCGAGCAGAAGCAACGGGAGCTGGCCGACTACCTGTGTGAGGAC GCCCAGCAGCTGTCCCTGGAGGACACGTTCAGCACCATGAAGGCTTTCCGGGACCTTTTC CTCCGCGCCCTGAAGGAGAACAAGGACCGGAAGGAGCAGGCGGCGAAGGCAGAGAGGAGG AAGCAGCAGCTGGCGGAGGAGGAGGCGCGGCGGCCTCGGGGAGAGGACGGGAAGCCTGTC AGGAAGGGGCCCGGGAAGCAGGAGGAGGTGTGTGTCATCGATGCCCTGCTGGCTGACATC AGGAAGGGCTTCCAGCTGCGGAAGACAGCCCGGGGCCGCGGGGACACCGACGGGGGCAGC AAGGCAGCCTCCATGGATCCCCCAAGAGCCACAGAGCCTGTGGCCACCAGTAACCCTGCA GGAGATCCCGTGGGCAGCACGCGCTGTCCCGCCTCTGAGCCCGGCCTTGATGCTACAACA GCCAGCGAGTCCCGGGGCTGGGACCTTGTAGACGCCGTGACCCCCGGCCCTCAGCCCACC CTGGAGCAGTTGGAGGAGGGTGGTCCACGGCCCCTGGAGAGGCGTTCTTCCTGGTATGTG GATGCCAGCGATGTCCTAACCACTGAGGATCCCCAGTGCCCCCAGCCCTTGGAGGGGGCC TGGCCGGTGACTCTGGGAGATGCTCAGGCCCTGAAGCCCCTCAAGTTCTCCAGCAACCAG CCCCCTGCAGCCGGAAGTTCAAGGCAAGATGCCAAGGATCCCACGTCCTTGCTGGGCGTC CTCCAGGCCGAGGCCGACAGCACAAGTGAGGGGCTGGAGGACGCTGTCCACAGCCGTGGT GCCAGACCCCCTGCAGCAGGCCCAGGTGGGGATGAGGACGAGGACGAGGAGGACACGGCC CCAGAGTCCGCACTGGACACATCCCTGGACAAGTCCTTCTCCGAGGATGCGGTGACCGAC TCCTCGGGGTCGGGCACACTCCCCAGGGCCCGGGGCCGGGCCTCAAAGGGGACCGGGAAG CGAAGGAAGAAGCGTCCCTCCAGGAGCCAGGAAGAGGTTCCCCCTGATTCTGATGATAAT AAAACAAAGAAACTGTGTGTGATCCAG |
| Restriction Sites | Please inquire |
| ACCN | NM_022489 |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_022489.3, NP_071934.3 |
| RefSeq Size | 4725 bp |
| RefSeq ORF | 3750 bp |
| Locus ID | 64423 |
| UniProt ID | Q27J81 |
| Domains | WH2 |
| Protein Families | Druggable Genome |
| Gene Summary | This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.[provided by RefSeq, Aug 2010] Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by orthologous data. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis
,Elizabeth J Brown, Johannes S Schlöndorff, Daniel J Becker, Hiroyasu Tsukaguchi, Andrea L Uscinski, Henry N Higgs, Joel M Henderson, Martin R Pollak,
Nature Genetics 42, 72-76 (20 December 2009) doi:10.1038/ng.505 Letter
[INF2]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216716 | INF2 (Myc-DDK-tagged)-Human inverted formin, FH2 and WH2 domain containing (INF2), transcript variant 1 |
CNY 13,040.00 |
|
| RC216716L3 | Lenti-ORF clone of INF2 (Myc-DDK-tagged)-Human inverted formin, FH2 and WH2 domain containing (INF2), transcript variant 1 |
CNY 14,350.00 |
|
| RC216716L4 | Lenti-ORF clone of INF2 (mGFP-tagged)-Human inverted formin, FH2 and WH2 domain containing (INF2), transcript variant 1 |
CNY 14,350.00 |
|
| RG216716 | INF2 (tGFP-tagged) - Human inverted formin, FH2 and WH2 domain containing (INF2), transcript variant 1 |
CNY 13,680.00 |
