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Hairless (HR) (NM_018411) Human Tagged Lenti ORF Clone
CAT＃: RC221977L3
- LentiORF®
Lenti ORF clone of Human hairless homolog (mouse) (HR), transcript variant 2, Myc-DDK-tagged
"NM_018411" in other vectors (4)
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CNY 13,210.00
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CNY 1,999.00
CNY 2,700.00
CNY 600.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | ALUNC; AU; HSA277165; HYPT4; MUHH; MUHH1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC221977).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_018411 |
| ORF Size | 3402 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_018411.3, NP_060881.2 |
| RefSeq Size | 4816 bp |
| RefSeq ORF | 3405 bp |
| Locus ID | 55806 |
| UniProt ID | O43593 |
| Protein Families | Druggable Genome, Transcription Factors |
| MW | 121.7 kDa |
| Gene Summary | This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221977 | HR (Myc-DDK-tagged)-Human hairless homolog (mouse) (HR), transcript variant 2 |
CNY 7,896.00 |
|
| RC221977L4 | Lenti ORF clone of Human hairless homolog (mouse) (HR), transcript variant 2, mGFP tagged |
CNY 13,210.00 |
|
| RG221977 | HR (tGFP-tagged) - Human hairless homolog (mouse) (HR), transcript variant 2 |
CNY 12,450.00 |
|
| SC304590 | HR (untagged)-Human hairless homolog (mouse) (HR), transcript variant 2 |
CNY 21,850.00 |
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