NRDE2 (NM_017970) Human Tagged Lenti ORF Clone
CAT#: RC224847L2
- LentiORF®
Lenti-ORF clone of NRDE2 (mGFP-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1
"NM_017970" in other vectors (6)
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CNY 14,560.00
Cited in 1 publication. |
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | mGFP |
Synonyms | C14orf102 |
Vector | pLenti-C-mGFP |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC224847).
|
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | NM_017970 |
ORF Size | 3492 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_017970.2 |
RefSeq Size | 3824 bp |
RefSeq ORF | 3495 bp |
Locus ID | 55051 |
UniProt ID | Q9H7Z3 |
MW | 132.5 kDa |
Gene Summary | Protein of the nuclear speckles that regulates RNA degradation and export from the nucleus through its interaction with MTREX an essential factor directing various RNAs to exosomal degradation (PubMed:30842217). Changes the conformation of MTREX, precluding its association with the nuclear exosome and interaction with proteins required for its function in RNA exosomal degradation (PubMed:30842217). Negatively regulates, for instance, the degradation of mRNAs and lncRNAs by inhibiting their MTREX-mediated recruitment to nuclear exosome (PubMed:30842217). By preventing the degradation of RNAs in the nucleus, it promotes their export to the cytoplasm (PubMed:30842217).[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Human nuclear RNAi-defective 2 (NRDE2) is an essential RNA splicing factor
,null,
RNA
,PubMed ID 30538148
[NRDE2]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC224847 | NRDE2 (Myc-DDK-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 |
CNY 12,160.00 |
|
RC224847L1 | Lenti-ORF clone of NRDE2 (Myc-DDK-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 |
CNY 14,560.00 |
|
RC224847L3 | Lenti-ORF clone of NRDE2 (Myc-DDK-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 |
CNY 7,600.00 |
|
RC224847L4 | Lenti-ORF clone of NRDE2 (mGFP-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 |
CNY 7,600.00 |
|
RG224847 | NRDE2 (tGFP-tagged) - Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 |
CNY 13,760.00 |
|
SC304549 | NRDE2 (untagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 |
CNY 12,976.00 |