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NRDE2 (NM_017970) Human Untagged Clone
CAT＃: SC304549
NRDE2 (untagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1
CNY 12,976.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C14orf102 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC304549 representing NM_017970.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGCGCTGTTCCCAGCCTTTGCGGGGCTTAGTGAGGCTCCCGATGGCGGGAGCTCCAGGAAAGAGTTA GACTGGCTGAGCAACCCAAGCTTTTGTGTTGGATCCATAACGTCCCTGAGCCAACAAACTGAAGCAGCT CCAGCCCATGTTTCTGAAGGGTTACCGCTGACAAGGAGTCATCTGAAATCAGAGTCTTCAGATGAAAGT GACACTAACAAAAAGCTCAAACAAACAAGTAGAAAAAAGAAGAAAGAGAAAAAGAAAAAAAGGAAGCAT CAGCATCATAAGAAAACAAAGAGGAAGCATGGGCCGTCGAGTAGCAGCAGGTCTGAGACAGACACCGAT TCTGAAAAGGACAAACCTTCCAGAGGCGTTGGAGGCAGTAAAAAGGAATCTGAGGAACCGAATCAAGGA AATAATGCTGCAGCTGATACTGGACATCGCTTTGTTTGGCTTGAGGACATTCAGGCTGTGACGGGAGAA ACCTTCAGAACAGATAAGAAACCAGATCCTGCGAACTGGGAGTACAAGTCTCTCTACCGAGGGGATATA GCAAGATACAAGAGGAAAGGAGACTCCTGCCTTGGCATTAACCCTAAGAAGCAGTGCATATCTTGGGAA GGGACTTCCACAGAGAAGAAGCATTCACGCAAGCAGGTTGAACGCTATTTTACTAAGAAGAGTGTGGGA TTAATGAACATCGATGGAGTTGCCATTAGCAGTAAAACTGAACCTCCCTCATCTGAGCCCATCTCCTTT ATACCAGTGAAGGACTTGGAAGATGCGGCTCCTGTTACAACCTGGTTGAATCCTCTGGGGATTTATGAT CAGTCAACCACACATTGGCTACAAGGACAGGGTCCTCCAGAGCAGGAATCAAAGCAGCCAGACGCACAG CCAGACAGCGAGAGTGCGGCTCTCAAGGCCAAGGTGGAGGAGTTTAACAGGAGGGTGCGGGAGAATCCT CGGGATACGCAGCTGTGGATGGCATTTGTTGCTTTTCAGGACGAGGTCATGAAAAGTCCTGGCCTGTAT GCCATCGAGGAAGGAGAGCAGGAAAAGCGAAAGAGGTCCCTGAAGCTCATTCTGGAGAAGAAGCTGGCC ATTCTGGAGCGGGCCATTGAGAGCAACCAGAGCAGTGTGGATCTGAAACTGGCCAAGCTGAAGCTCTGC ACAGAGTTCTGGGAGCCCTCCACTCTGGTCAAAGAGTGGCAGAAACTGATATTTTTGCATCCCAATAAT ACAGCCCTTTGGCAGAAATACCTTTTATTTTGCCAGAGCCAGTTTAGTACCTTTTCGATATCAAAAATT CACAGTCTTTATGGAAAATGCTTGAGCACTTTGTCTGCTGTTAAGGACGGCAGCATCTTATCTCACCCT GCGTTGCCTGGCACGGAAGAGGCCATGTTTGCACTCTTTCTTCAGCAGTGCCACTTTCTGCGGCAGGCT GGCCACTCTGAGAAGGCCATCTCATTGTTCCAGGCCATGGTGGACTTCACCTTCTTCAAACCCGACAGC GTGAAAGATCTGCCTACCAAAGGACAGGTGGAATTCTTTGAACCCTTTTGGGACAGTGGAGAGCCCCGG GCTGGGGAGAAGGGAGCCCGAGGCTGGAAGGCGTGGATGCACCAGCAGGAACGAGGTGGCTGGGTGGTC ATCAACCCAGATGAGGATGACGATGAACCAGAAGAGGATGACCAGGAAATAAAAGATAAGACTCTGCCC AGGTGGCAGATCTGGCTTGCTGCTGAGCGTTCCCGTGACCAGAGGCACTGGCGGCCCTGGCGCCCTGAT AAGACCAAGAAGCAAACCGAGGAAGACTGTGAGGATCCCGAGAGACAGGTGTTGTTTGATGATATTGGG CAATCTTTGATCAGACTTTCCAGCCATGATCTTCAGTTCCAGCTGGTGGAGGCCTTCCTGCAGTTCTTG GGTGTGCCTTCTGGCTTTACTCCTCCAGCCTCCTGTCTTTATCTGGCCATGGATGAGAACAGCATCTTT GATAATGGACTTTATGATGAAAAGCCCTTGACTTTTTTCAACCCTTTGTTTTCTGGGGCTAGCTGTGTT GGCCGCATGGATAGGTTGGGCTATCCTCGCTGGACCAGGGGTCAGAACCGAGAGGGCGAGGAGTTCATC CGCAATGTCTTCCACCTTGTCATGCCTTTATTTTCAGGCAAAGAGAAGTCCCAGCTCTGCTTCTCCTGG TTACAGTATGAGATTGCAAAGGTCATTTGGTGCCTGCACACTAAAAACAAGAAGAGATTAAAGTCTCAA GGGAAGAACTGCAAAAAACTAGCCAAGAATCTCCTTAAGGAGCCAGAAAACTGCAACAACTTTTGCCTG TGGAAGCAGTATGCACATCTGGAGTGGTTGCTTGGCAACACGGAGGATGCCAGAAAAGTTTTTGACACA GCACTTGGCATGGCAGGAAGCAGAGAACTGAAAGACTCTGACCTCTGTGAGCTCAGTCTGCTCTATGCT GAGCTGGAGGTGGAGCTGTCGCCAGAAGTGAGAAGGGCTGCCACAGCTCGAGCTGTTCACATATTAACC AAGCTGACTGAGAGCAGCCCCTATGGGCCCTACACTGGACAGGTGTTGGCTGTTCACATTTTGAAAGCG CGAAAGGCTTATGAGCACGCACTGCAGGACTGTTTGGGTGACAGCTGTGTCTCCAATCCAGCTCCCACC GATTCCTGTAGCCGCCTAATTAGCCTGGCTAAATGCTTCATGCTCTTCCAGTATTTGACCATAGGGATT GATGCTGCTGTGCAGATATACGAACAGGTGTTTGCAAAACTGAACAGTTCTGTTTTCCCAGAAGGCTCT GGCGAGGGGGACAGTGCCAGCTCCCAGAGTTGGACCAGTGTTCTCGAAGCCATCACACTGATGCACACG AGCCTGCTGAGATTCCACATGAAAGTGAGTGTTTACCCGCTGGCCCCTCTGCGAGAGGCACTCTCACAG GCTTTAAAGTTGTATCCAGGCAACCAGGTTCTTTGGAGGTCCTATGTACAGATTCAGAATAAGTCCCAC AGTGCCAGCAAAACCAGGAGATTTTTTGACACAATCACCAGGTCTGCCAAACCCTTGGAGCCTTGGTTG TTTGCAATTGAAGCTGAGAAACTGAGGAAGAGACTGGTGGAAACTGTCCAGAGGTTAGACGGTAGAGAG ATCCACGCCACAATTCCTGAGACCGGCTTAATGCATCGGATCCAAGCCCTGTTTGAAAATGCCATGCGC AGCGACAGTGGCAGCCAGTGCCCCTTGCTGTGGAGGATGTATTTGAACTTTCTGGTTTCCTTAGGAAAT AAAGAAAGAAGCAAAGGTGTATTCTACAAAGCACTTCAGAATTGCCCTTGGGCAAAGGTGTTGTACCTG GACGCCGTGGAGTATTTCCCCGATGAGATGCAGGAGATCCTGGACCTGATGACTGAGAAGGAGCTCCGG GTGCGCCTGCCGCTGGAGGAGCTGGAGCTGCTGCTGGAGGATTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_017970 |
| Insert Size | 3495 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_017970.3 |
| RefSeq Size | 4026 bp |
| RefSeq ORF | 3495 bp |
| Locus ID | 55051 |
| UniProt ID | Q9H7Z3 |
| MW | 132.7 kDa |
| Gene Summary | Protein of the nuclear speckles that regulates RNA degradation and export from the nucleus through its interaction with MTREX an essential factor directing various RNAs to exosomal degradation (PubMed:30842217). Changes the conformation of MTREX, precluding its association with the nuclear exosome and interaction with proteins required for its function in RNA exosomal degradation (PubMed:30842217). Negatively regulates, for instance, the degradation of mRNAs and lncRNAs by inhibiting their MTREX-mediated recruitment to nuclear exosome (PubMed:30842217). By preventing the degradation of RNAs in the nucleus, it promotes their export to the cytoplasm (PubMed:30842217).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224847 | NRDE2 (Myc-DDK-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 |
CNY 12,160.00 |
|
| RC224847L1 | Lenti-ORF clone of NRDE2 (Myc-DDK-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 |
CNY 14,560.00 |
|
| RC224847L2 | Lenti-ORF clone of NRDE2 (mGFP-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 |
CNY 14,560.00 |
|
| RC224847L3 | Lenti-ORF clone of NRDE2 (Myc-DDK-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 |
CNY 7,600.00 |
|
| RC224847L4 | Lenti-ORF clone of NRDE2 (mGFP-tagged)-Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 |
CNY 7,600.00 |
|
| RG224847 | NRDE2 (tGFP-tagged) - Human chromosome 14 open reading frame 102 (C14orf102), transcript variant 1 |
CNY 13,760.00 |
