Angiomotin (AMOT) (NM_001113490) Human Tagged ORF Clone
CAT#: RC226319
- TrueORF®
AMOT (Myc-DDK-tagged)-Human angiomotin (AMOT), transcript variant 1
ORF Plasmid: tGFP
"NM_001113490" in other vectors (6)
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CNY 12,072.00
Cited in 2 publications. |
CNY 300.00
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
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ACCN | NM_001113490 |
ORF Size | 3252 bp |
OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001113490.1, NP_001106962.1 |
RefSeq ORF | 3255 bp |
Locus ID | 154796 |
UniProt ID | Q4VCS5 |
MW | 117.9 kDa |
Gene Summary | This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
Citations (2)
The use of this cDNA Clones has been cited in the following citations: |
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Conditional knockout of TFPI-1 in VSMCs of mice accelerates atherosclerosis by enhancing AMOT/YAP pathway
,Xiao, J;Jin, K;Wang, J;Ma, J;Zhang, J;Jiang, N;Wang, H;Luo, X;Fei, J;Wang, Z;Yang, X;Ma, D;,
Int. J. Cardiol.
,PubMed ID 27875740
[AMOT]
|
Angiomotin decreases lung cancer progression by sequestering oncogenic YAP/TAZ and decreasing Cyr61 expression
,Hsu, YL;Hung, JY;Chou, SH;Huang, MS;Tsai, MJ;Lin, YS;Chiang, SY;Ho, YW;Wu, CY;Kuo, PL;,
Oncogene
,PubMed ID 25381822
[AMOT]
|
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC226319L1 | Lenti-ORF clone of AMOT (Myc-DDK-tagged)-Human angiomotin (AMOT), transcript variant 1 |
CNY 14,472.00 |
|
RC226319L2 | Lenti-ORF clone of AMOT (mGFP-tagged)-Human angiomotin (AMOT), transcript variant 1 |
CNY 12,730.00 |
|
RC226319L3 | Lenti-ORF clone of AMOT (Myc-DDK-tagged)-Human angiomotin (AMOT), transcript variant 1 |
CNY 12,730.00 |
|
RC226319L4 | Lenti-ORF clone of AMOT (mGFP-tagged)-Human angiomotin (AMOT), transcript variant 1 |
CNY 14,472.00 |
|
RG226319 | AMOT (tGFP-tagged) - Human angiomotin (AMOT), transcript variant 1 |
CNY 13,672.00 |
|
SC319022 | AMOT (untagged)-Human angiomotin (AMOT), transcript variant 1 |
CNY 20,810.00 |
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