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COP (CARD16) (NM_052889) Human Tagged ORF Clone
CAT＃: RG211537
- TrueORF®
CARD16 (tGFP-tagged) - Human caspase recruitment domain family, member 16 (CARD16), transcript variant 2
ORF Plasmid: DDK
"NM_052889" in other vectors (4)
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CNY 2,800.00
CNY 4,370.00
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | COP; COP1; PSEUDO-ICE |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG211537 representing NM_052889
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGAAAAGCCATGGCCGACAAGGTCCTGAAGGAGAAGAGAAAGCTGTTTATCCATTCCATGGGTGAAG GTACAATAAATGGCTTACTGGATGAATTATTACAGACAAGGGTGCTGAACCAGGAAGAGATGGAGAAAGT AAAACGTGAAAATGCTACAGTTATGGATAAGACCCGAGCTTTGATTGACTCCGTTATTCCGAAAGGGGCA CAGGCATGCCAAATTTGCATCACATACATTTGTGAAGAAGACAGTTACCTGGCAGAGACGCTGGGACTCT CAGCAGGTCCGATACCTGGAAAT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG211537 representing NM_052889
Red=Cloning site Green=Tags(s) MRKAMADKVLKEKRKLFIHSMGEGTINGLLDELLQTRVLNQEEMEKVKRENATVMDKTRALIDSVIPKGA QACQICITYICEEDSYLAETLGLSAGPIPGN TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_052889 |
| ORF Size | 303 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_052889.2, NP_443121.1 |
| RefSeq Size | 758 bp |
| RefSeq ORF | 294 bp |
| Locus ID | 114769 |
| UniProt ID | Q5EG05 |
| Gene Summary | Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211537 | CARD16 (Myc-DDK-tagged)-Human caspase recruitment domain family, member 16 (CARD16), transcript variant 2 |
CNY 1,200.00 |
|
| RC211537L3 | Lenti ORF clone of Human caspase recruitment domain family, member 16 (CARD16), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC211537L4 | Lenti ORF clone of Human caspase recruitment domain family, member 16 (CARD16), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| SC309071 | CARD16 (untagged)-Human caspase recruitment domain family, member 16 (CARD16), transcript variant 2 |
CNY 1,200.00 |
