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Eri1 (NM_001014143) Rat Untagged Clone
CAT＃: RN204120
Eri1 (untagged ORF) - Rat three prime histone mRNA exonuclease 1 (Thex1), (10 ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | RGD1308378; Thex1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN204120 representing NM_001014143
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGACGAGCGGGGCCGGGAGCATGGCGGCGACGCGGCGCAGCAGAAGACGCCGCGGCCAGAGTGTG AGGAGTCCCGGCCGCTGAGCGTGGAGAAAAAGCAGCGATGCAGACTTGATGGCAAAGACACAGATGGATC TAAGTTCATAACCTCCAATGGCGGTGACTTCAGTGACCCGGTTTACAAAGAGATTGCAATGACAAATGGT TGTATCAACAGGATGAGCAAGGAGGAGCTCAGAGCTAAACTTTCAGAATTCAAGCTTGAAACAAGAGGAG TCAAGGATGTTCTAAAGAAGAGACTGAAAAACTATTACAAGAAGCAGAAGCTGATGCTGAAAGAAAGCAA CGCCGTGGACAGTTACTATGACTATATTTGTATTATTGACTTTGAGGCCACCTGTGAAGAGGGGAACCCA GCCGAGTTCCTACATGAAATTATTGAGTTTCCTGTTGTTCTGTTGAATACACACAGCTTAGAGATCGAAG ACACGTTTCAGCAGTATGTGAGACCAGAGGTGAATTCTCAGCTTTCAGAGTTCTGCATTGGTCTTACTGG AATTACTCAGGATCAGGTAGACAGAGCCGATGCTTTCCCTCAGGTCCTGAAAAAAGTAATCGAGTGGATG AAGTCAAAGGAGTTGGGAACTAAGTACAAATACTGCATATTAACAGATGGTTCCTGGGATATGAGTAAGT TCTTAAACATCCAGTGCCAACTAAGCAGACTCAAGTACCCTTCTTTTGCTAAAAAGTGGATCAATATTCG CAAGTCTTACGGAAACTTTTATAAGGTTCCAAGAAGCCAGACCAAACTAACAATAATGCTTGAAAAATTA GGCATGGATTATGATGGGCGACCTCACAGTGGTCTTGATGACTCTAAGAACATTGCTAGAATAGCGGTTC GGATGCTTCAGGATGGATGTGAACTTCGAATCAATGAAAAACTGCACGGAGGACAGCTAATGAGTGTGTC CTCATCCTTACCAGTAGAGGGCGCTCCAGCCCCACAGATGCCGCATAGTAGAAAGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001014143 |
| Insert Size | 1038 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001014143.1, NP_001014165.1 |
| RefSeq Size | 2896 bp |
| RefSeq ORF | 1038 bp |
| Locus ID | 361159 |
| UniProt ID | Q5FVR4 |
| Gene Summary | RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Binds with high affinity to the 3' side of the stem-loop structure and to the downstream cleavage product (DCP) of histone pre-mRNAs. Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR204120 | Eri1 (Myc-DDK-tagged ORF) - Rat three prime histone mRNA exonuclease 1 (Thex1), (10 ug) |
CNY 3,990.00 |
|
| RR204120L3 | Lenti ORF clone of Eri1 (Myc-DDK-tagged ORF) - Rat three prime histone mRNA exonuclease 1 (Thex1), (10 ug) |
CNY 6,080.00 |
|
| RR204120L4 | Lenti ORF clone of Eri1 (mGFP-tagged ORF) - Rat three prime histone mRNA exonuclease 1 (Thex1), (10 ug) |
CNY 6,650.00 |
