Eri1 (NM_001014143) Rat Tagged ORF Clone Lentiviral Particle
CAT#: RR204120L4V
- LentiORF®
-
Lenti ORF particles, Eri1 (GFP-tagged ORF) - Rat three prime histone mRNA exonuclease 1 (Thex1), 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | Eri1 (NM_001014143) Rat Tagged ORF Clone Lentiviral Particle |
Synonyms | RGD1308378; Thex1 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001014143 |
ORF Size | 1035 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR204120).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001014143.1, NP_001014165.1 |
RefSeq Size | 2896 bp |
RefSeq ORF | 1038 bp |
Locus ID | 361159 |
Gene Summary | RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Binds with high affinity to the 3' side of the stem-loop structure and to the downstream cleavage product (DCP) of histone pre-mRNAs. Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA (By similarity).[UniProtKB/Swiss-Prot Function] |
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