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Klhl15 (NM_001108021) Rat Untagged Clone
CAT＃: RN206896
Klhl15 (untagged ORF) - Rat kelch-like 15 (Drosophila) (Klhl15), (10 ug)
CNY 7,790.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | RGD1563101 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN206896 representing NM_001108021
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCAGGGGACGTGGAAGGATTCTGTTCCTCCATCCATGACACCAGTGTCTCTGCTGGGTTCAGAGCAC TGTATGAGGAGGGATTGCTTCTTGATGTCACTCTGGTTATTGAAGACCATCAGTTCCAGGCCCATAAAGC CCTCCTGGCCACCCAGAGTGATTACTTCAGAATTATGTTCACAGCAGATATGAGGGAACGAGATCAGGAC AAAATTCATTTGAAGGGTCTAACAGCTACTGGTTTCAGCCACGTTCTTCAGTTTATGTATTATGGAACTA TAGAACTAAGTATGAATACTGTTCATGAAATCCTTCAGGCAGCAATGTATGTTCAGCTTATAGAAGTGGT GAAATTCTGCTGCTCTTTTCTCTTAGCCAAAATCTGCTTAGAAAATTGTGCGGAAATTATGAGACTGTTA GATGATTTTGGTGTTAACATCGAGGGAGTCAGGGAGAAGCTGGATGCCTTTCTGCTAGACAACTTCGTGC CACTCATGTCCAGGCCTGACTTCCTGTCTTATCTGAGCTTTGAGAAGCTCATGTCTTATTTGGATAATGA TCATCTGAGCAGGTTTCCAGAAATAGAGCTGTACGAGGCTGTGCAGTCTTGGCTGCGACATGATAGACGA CGGTGGAGACACACAGATACCATCATTCAGAACATCAGGTTTTGTCTGATGACTCCATCCAGCGTTTTTG AGAAGGTTAAAACATCAGAATTTTATAGATACTCCCGACAGCTGCGGTATGAAGTTGACCAAGCATTGAA TTACTTCCAAAATGTTCACCAGCAACCCTTGTTGGACATGAAATCAAGCCGTATTCGTTCTGCCAAACCC CAAACTACAGTATTCCGAGGAATGATTGGACATAGCATGGTTAATAGTAAAATACTCCTGTTAAAGAAAC CAAGAGTCTGGTGGGAACTGGAGGGCCCCCAAGTACCTCTAAGACCAGACTGCCTTGCCATTGTCAATAA TTTTGTGTTCCTGCTAGGTGGCGAAGAGCTGGGCCCCGATGGAGAATTCCATGCCTCTTCGAAAGTGTTC AGGTATGATCCAAGACAAAATTCTTGGCTGCGTATGGCAGACATGTCTGTACCACGTTCAGAATTTGCTG TTGGTGTCATTGGGAAGTTTATTTATGCTGTAGCAGGCAGAACAAGAGATGAAACTTTCTACTCAACAGA AAGATACGATATCACTAACGATAAATGGGAATTCGTAGATCCTTATCCAGTTAACAAATATGGACATGAG GGGACAGTGCTCAATAACAAGTTGTTTATCACTGGAGGAATCACTTCATCTTCCACATCTAAACAGGTGT GTGTATTTGACCCCAGTAAAGAAGGGACCATAGAACAGCGGACCAGGAGAACTCAAGTGGTTACCAACTG CTGGGAGAATAAAAGCAAGATGAATTATGCTAGATGCTTTCACAAGATGATCTCTTATAATGGCAAGCTT TATGTCTTTGGTGGTGTCTGTGTGATCTTGAGGGCCTCTTTTGAATCTCAGGGCTGCCCTTCCACAGAGG TGTATAACCCAGATACTGATCAATGGACCATCTTGGCATCTATGCCAATTGGTAGAAGTGGTCACGGTGT GACTGTGCTGGACAAACAAATCATGGTCCTTGGGGGCCTTTGTTATAATGGTCATTACAGTGATTCCATT CTCACCTTTGACCCAGATGAAAATAAGTGGAAAGAAGATGAGTACCCTCGGATGCCCTGCAAGCTGGATG GTTTACAGGTGTGCAACCTCCATTTTCCGGACTATGTACTGGATGAGGTTAGGCGTTGCAACTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001108021 |
| Insert Size | 1815 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001108021.1, NP_001101491.1 |
| RefSeq Size | 1969 bp |
| RefSeq ORF | 1815 bp |
| Locus ID | 314111 |
| UniProt ID | D3ZA50 |
| Gene Summary | Substrate-specific adapter for CUL3 E3 ubiquitin-protein ligase complex. Acts as an adapter for CUL3 to target the serine/threonine-protein phosphatase 2A (PP2A) subunit PPP2R5B for ubiquitination and subsequent proteasomal degradation, thus promoting exchange with other regulatory subunits and regulating PP2A holoenzyme composition. Acts as an adapter for CUL3 to target the DNA-end resection factor RBBP8/CtIP for ubiquitination and subsequent proteasomal degradation. Through the regulation of RBBP8/CtIP protein turnover, plays a key role in DNA damage response, favoring DNA double-strand repair through error-prone non-homologous end joining (NHEJ) over error-free, RBBP8-mediated homologous recombination (HR).[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR206896 | Klhl15 (Myc-DDK-tagged ORF) - Rat kelch-like 15 (Drosophila) (Klhl15), (10 ug) |
CNY 7,790.00 |
|
| RR206896L3 | Lenti ORF clone of Klhl15 (Myc-DDK-tagged ORF) - Rat kelch-like 15 (Drosophila) (Klhl15), (10 ug) |
CNY 9,600.00 |
|
| RR206896L4 | Lenti ORF clone of Klhl15 (mGFP-tagged ORF) - Rat kelch-like 15 (Drosophila) (Klhl15), (10 ug) |
CNY 10,550.00 |
