Clock (NM_001289832) Rat Untagged Clone
CAT#: RN217246
Clock (untagged) - Rat clock circadian regulator (Clock), transcript variant 2
CNY 7,980.00
货期*
4周
规格
Product images
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经常一起买 (3)
Specifications
Product Data | |
Type | Rat Untagged Clone |
Tag | Tag Free |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>RN217246 representing NM_001289832
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTTGTTTACCGTAAGCTGTAGTAAAATGAGCTCAATTGTTGACAGAGATGACAGTAGTATTTTTGATG GATTGGTGGAAGAAGATGACAAGGACAAAGCAAAAAGAGTATCTAGAAACAAATCAGAAAAGAAACGTAG AGATCAGTTCAATGTACTCATTAAGGAACTGGGGTCTATGCTTCCTGGTAATGCTAGAAAGATGGACAAG TCTACTGTTCTACAGAAGAGCATTGATTTTTTACGCAAACATAAAGAGATCACTGCACAGTCAGATGCTA GTGAAATTCGACAGGACTGGAAACCTACATTCCTTAGTAATGAAGAGTTTACACAATTAATGTTAGAGGC TCTTGATGGTTTTTTTTTAGCGATCATGACAGATGGAAGTATAATATATGTATCTGAGACGGTAACTTCG TTACTTGAACATTTACCATCTGATCTTGTGGATCAAAGTATATTTAATTTTATCCCAGAGGGAGAACATT CAGAGGTTTATAAGATACTATCTACTCACCTGCTGGAAAGTGACTCCTTAACCCCCGAGGACTTAAAATC AAAAAATCAGTTAGAATTCTGTTGTCACATGCTTCGAGGAACAATAGACCCAAAGGAGCCATCCACCTAT GAATATGTGAGATTTATAGGAAATTTTAAATCTTTAAACAGTGTATCAACTTCAACACATAATGGTTTCG AAGGAACTATACAGCGCACACACAGGCCTTCTTATGAAGATAGAGTTTGTTTCGTAGCTACTGTCAGATT AGCTACCCCTCAGTTCATCAAGGAAATGTGTACTGTTGAAGAACCGAATGAAGAGTTCACATCTAGACAC AGTTTAGAATGGAAGTTTCTATTTCTAGATCACAGGGCGCCGCCAATCATAGGCTATCTGCCGTTTGAAG TCCTGGGAACATCAGGCTATGATTACTATCATGTGGACGACCTAGAAAGTCTGGCAAAATGTCATGAGCA CTTAATGCAATATGGAAAAGGCAAATCATGTTACTATAGGTTCTTGACCAAAGGACAGCAGTGGATTTGG CTTCAGACTCATTACTATATCACTTACCATCAGTGGAACTCAAGGCCAGAGTTCATCGTTTGTACTCACA CTGTAGTAAGTTATGCAGAAGTTAGGGCTGAAAGACGGCGAGAACTTGGCGTTGAGGAGTCTCTTCCCGA GACAGCTGCTGACAAAAGCCAAGATTCTGGGTCTGACAATCGTATAAACACAGTGAGTCTCAAGGAAGCA CTGGAAAGGTTCGATCACAGCCCAACTCCTTCTGCCTCCTCCAGAAGCTCAAGAAAGTCCTCGCACACAG CAGTCTCAGACCCTTCCTCAACGCCGACAAAGATCCCCACTGATACTAGCACTCCTCCCAGACCGCACCT GCCAGCTCATGAGAAGATGACACAGCGGAGGTCATCCTTCAGTAGTCAGTTTCAGCTTTCAGCTCAGTTA GGAGCCATGCAGCATCTCAAAGACCAGCTAGAGCAGCGGACACGCATGATAGAAGCAAATATTCATCGGC AGCAAGAAGAACTAAGGAAAATTCAAGAACAACTTCAAATGGTCCATGGTCAAGGGCTACAGATGTTTTT GCAGCAATCAAACCCTGGACTGAATCTTGGTTCTGTTCAACTTTCCTCTGGAAATTCCAATATCCAGCAA CTCACACCTATAAATATGCAAGGCCAAGTTGTCCCTGTTAACCAGATTCAGAGTGGGGTGAATGCTGGCC ATGTCAGCACAGGCCAGCACATGATCCAGCAGCAGACTTTACAAAGTACATCAACTCAGAGTCAACAGAG TGTAATGAGTGGACACAGTCAGCCAACGTCTCTTCCAAACCAGACGCCGAGCACTCTGACAGCCCCACTG TACAATACGATGGTGATCTCTCAGCCTGCGGCTGGGAGCATGGTCCCGATTCCATCCAGTATGCCGCAGA ATAGCACCCAGAGTGCTACAGTCACCACGTTCACTCAGGACAGACAGATAAGGTTTTCTCAAGGTCAGCA ACTTGTGACCAAATTAGTGACTGCTCCTGTAGCTTGTGGGGCCGTCATGGTGCCAAGTACCATGCTTATG GGTCAGGTAGTGACTGCCTATCCTACTTTTGCCACACAACAGCAGCAGGCACAGGCCTTGTCAGTAACAC AGCAACAGCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCCGCAGCAGGCGCAGCAGCC CCAGTCACAGCAGAGTTCCCAGGACCAGCCGCATCCTTCAGTTCAGCAGCCAGCTCAGCTGACCCAGCCA CCACAACAGTTCTTACAGACATCTCGGTTGCTCCATGGGAATCCTTCGACACAGCTCATCCTCTCCGCTG CCTTTCCACTACAACAGAGCACTTTCCCTCCTTCGCACCACCAGCAACACCAGCAACAGCAGCTCCATCG GCACAGGACTGACAGCCTGACTGACCCTTCCAAGGTCCAGCCACAGTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001289832 |
Insert Size | 2499 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001289832.1, NP_001276761.1 |
RefSeq Size | 9201 bp |
RefSeq ORF | 2499 bp |
Locus ID | 60447 |
UniProt ID | Q9WVS9 |
Gene Summary | The protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix-loop-helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with Arntl (Bmal1) that binds E-box enhancer elements upstream of Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2) genes and activates transcription of these genes. Per and Cry proteins heterodimerize and repress their own transcription by interacting in a feedback loop with Clock/Arntl complexes. Polymorphisms in this gene may be associated with behavioral changes, obesity, and metabolic syndrome. Two transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014] Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (S) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RR217246 | Clock (myc-DDK-tagged) - Rat clock circadian regulator (Clock), transcript variant 2 |
CNY 7,980.00 |
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