IL28 Receptor alpha (IFNLR1) (AK094159) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Vector	pCMV6-XL5
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for AK094159, the custom clone sequence may differ by one or more nucleotides AGTTTCTTGCTCTTCTTCACTATAATGGGGTTTGTCATCAGCTCCCCAAAATATGGGAAGCACAGAGCAG GTGGTGGCTGAAGGTGGGGTATCCTGTGAAACCATATTTAAGATCAGAGCCCTTGGTCCATTGTGTTGTA ATCAGCTGGCTCAGGAAAGAACACCTGGCTGTCCAGAGCTCTACACCTACTGCACTGGGTGTGAAAGGAG GCCTGAGAACCCATGGGTCCCAAACCCACCCCACTCCAAATTATCATCCAGTATTGAGAACTCTGACACC AAATTCTCACGGAGCATATGTTTATGCAGTTTTACATTTAATTTCTCATTACATTACAATTGGGAAACTG AGGCCCCAGAAGAGGCAGAGACTGGTCCAGATCTCAGGAGGTGGGCAGGCTCCAGAGCATTAGAGAGGGC TCCAGCTTCCTAGGCCTTGGCTCCGTCCCACTTATCAGGTTTGTTTTCGAAATTAGAGTCTGTAGCTACA CATTCAGGAGCACAGAAAATGAGCAGATTCAGGGTTCTGTTCACATGGGACCTCTCCATGTCAGTTTCAA GATAACAGGACTGGGGTTCTGCATCCAGCTCTGAGGGCAACTGGAAGTAAAATGAGCTATGCTCCACCTC AGCCTAATGTAGACAGTGCCTACAGGAAAGCCTGTTTTCTTCCTCATAAATAGGGGTGCCTGAAGTGGGT GACCTTGATGATTTCACATACTCATAAGTGTCTGCCAGCCTGGATTCTTGCTCTGAGACTGCAAAAATGC ACCCACTCTGCAGATCCTTCAAATCAGAGGGAGGCATGGCCACTTGAGAGGCATCTTGGGTAGATGAAGA TGAGACAGAGTTAAATGTGCCAGAGCACTGGACTCTGAGGCTGAGGTCCACGGAAAATCTCAGCTACTGT TGCGTTCTTAAGGTCCTCATTTGAAAGTGGTAGAAAATAATTTCACTGGATAAGGGGAGGATACCTCATG AGTAAATAGCACAACCAAAAAGGTGGAGGCAAAGAGAGGGCAAAACGGGATTCCTAGGTCACTCATTATA CTTGGGGCCTTCAGATCCTGCTACTTTATCCCCTAGGACCTTGAAGAACCAGTGTCTTGAGGACAGAAAA ATCAAGGTATCAGATTTGTTCAGTAGTGCTCCTGCTTGGGGCTGTAGGGTTAGTGATGGCCAGGAGGTGG TTACAGCCTACTGTGTTTCTGATGCCCACTGAGCTTTGCTGGAGCAGCTGGAACAAGTAACAGTCACACA CCTCATGTTGTTATCAGTGATGTCCACATTATCATGTGGTCAAAAGGGGAAGGGATATTAGAGATCCCCC ATATAATCACTTAGCCAGTCTTTTTTCCCTTGCGCTCACCATTTGCCAGCGACCCTGGTGGGTCCAACAT GTGGTACAGAAAACTATTACATCATGTCTGCACCCCCCAACCCAGGACCAAACAGTCTGAGGACCGCTGG ACAAAAGCACTAAAGCAAGTATATGTGAAAGAAAAAAGCAAGGACTATAATATAAAGTAGATTATTGAGA AGAAAACCTGGAAAATTATTGCATGGGAGGACCTCAGGCCTCACTGAGGTGACTTTTAATCCATGATGAG GATGACAGCAGGGAGGCATCTGCACAAGCATGTGTCAGGGAGAAGCCACCCTTAGTGAAAAGACTCATAG GTGTGAGTTTGGCAGAGGTAAAAAGGGACTAGTTTGGCTGCAGACAGCCTGAGAAAGAGATAAGCAGAGG GATGGAGAATCCTAGGGCCTGGGAGATGAGGTTAGATATCTGCTCCTTTCTGACAACATTGCCCTAAAAG TCAGCATTTTCAACAACATATAATATCTCATAATGTGTGTGGACCAGAATCTGGACACAGTTCAGCTGGC TACCTCTGCCTTCAGGTCTTTTATGAGACTGGGGGCTGTGGTCTTAACTGAAGCTGGACTGGGAAAGCAT GAGCCTTTAAGCTGACTCATGTGAAAATTGACAGGGTTTAGTGTGGACAGAGAGCCTGACTTTCCTTCTC TCTACTCATCTGAGCACCGCCTCACCCTTTGTTATGTGGGTCTCTACACGGAGCATCTCATAGCATTGGA GCTTGCTTCCTGTGTTTGAGGAATACAATAGACAGAATTAGACAAAAAGGTTTACACAAAAAGAGACAGA AAGATCGAGGGCGCAAACGAGAAAAACCCAGTAGGAGAAAAATTAGAGCTTTAAAAACATCTTGACAGGG TGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGATGCTGAGACGTGTGGATCGCCTGAGGTCAAGGG TTTGAAACCAACCTGGACAACATGGTGAAACCACCGTCTCTTCTAAAAATACAAAATGAGCCTGATGTGG TGGCGCATGCCTGTAATCCCAGCTACTTGGGAGACTGAGGCAGGAGAATCAATTGAACCTGGGAGGCGAA GGTTCCAGTAAGCCGAGATCACACCACTGCACTCCAGCCTGGGATACAAGAGTGAAACTGTGTCTC 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for AK094159 unedited NNNNGGGGGTTCACAATTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGAA CATTTTAACAAAAACAAAAGAAACAAACTGGCAACAAATATGTGAAGTTTATATTACAAA GATGCTCACTTATCCACTCTAAAGAGAGCTTTTAGAATTTGATTTAAAATACGGCAAAGA CCATTATCCCACNNACTTCACAGAAAAAATAAATTTAAGCAGCTGTTAACACATGAATGT ATTATCAAGCTCAGATATAATCAAAATTAAATATTTGACAAGAGATTCTACAGTTTGGGA GAAATAGAAGTGTTTTTTTTCTTTTCCCCAGGCCCACAAGTCTAGTTTCTTGCTCTTCTT CACTATAATGGGGTTTGTCATCAGCTCCCCAAAATATGGGAAGCACAGAGCAGGTGGTGG CTGAAGGTGGGGTATCCTGTGAAACCATATTTAAGATCAGAGCCCTTGGTCCATTGTGTT GTAATCAGCTGGCTCAGGAAAGAACACCTGGCTGTCCAGAGCTCTACACCTACTGCACTG GGTGTGAAAGGAGGCCTGAGAACCCATGGGTCCCAAACCCACCCCACTCCAAATTATCAT CCAGTATTGAGAACTCTGACACCAAATTCTCACAGAGCATATGTTTATGCAGTTTTACAT TTAATTTCTCATTACATTACAATTGGGAAACTGAGGTCCCAGAAGAGGCAGAGACTGGTC CAGATCTCAGGAGGTGGGCAGGCTCCAGAGCATTAGAGAGGGCTCCAGCTTCCTAGGCCT TGGCACCGTCCCACTTATCANGNNTTGTTTTCGAAATTAGAGTCTGTAGCTACACATTCA GGAGCACAGAAAATGAGCAGATTCAGGGNTCTGTTCACATGGGGTCCTCTNCATGTCAGT T
Restriction Sites	NotI-NotI
ACCN	AK094159
Insert Size	3000 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	AK094159.1
RefSeq Size	2516 bp
RefSeq ORF	2516 bp
Locus ID	163702
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
Gene Summary	The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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