United States
Germany
Japan
United Kingdom
China
Cytochrome P450 17A1 (CYP17A1) (NM_000102) Human Untagged Clone
CAT＃: SC102224
CYP17A1 (untagged)-Human cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1)
CNY 3,792.00
| Cited in 3 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CPT7; CYP17; P450C17; S17AH |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_000102 edited
ATAGGGCGGCCGCGAATTCGGCACGAGACTGCTGTCTATCTTGCCTGCCGGCACCCAGCC ACCATGTGGGAGCTCGTGGCTCTCTTGCTGCTTACCCTAGCTTATTTGTTTTGGCCCAAG AGAAGGTGCCCTGGTGCCAAGTACCCCAAGAGCCTCCTGTCCCTGCCCCTGGTGGGCAGC CTGCCATTCCTCCCCAGACACGGCCATATGCATAACAACTTCTTCAAGCTGCAGAAAAAA TATGGCCCCATCTATTCGGTTCGTATGGGCACCAAGACTACAGTGATTGTCGGCCACCAC CAGCTGGCCAAGGAGGTGCTTATTAAGAAGGGCAAGGACTTCTCTGGGCGGCCTCAAATG GCAACTCTAGACATCGCGTCCAACAACCGTAAGGGTATCGCCTTCGCTGACTCTGGCGCA CACTGGCAGCTGCATCGAAGGCTGGCGATGGCCACCTTTGCCCTGTTCAAGGATGGCGAT CAGAAGCTGGAGAAGATCATTTGTCAGGAAATCAGTACATTGTGTGATATGCTGGCCACC CACAACGGACAGTCCATAGACATCTCCTTTCCTGTCTTCGTGGCGGTAACCAATGTCATC TCCTTGATCTGCTTCAATACCTCCTACAAGAATGGGGACCCTGAGTTGAATGTCATACAG AATTACAATGAAGGCATCATAGACAACCTGAGCAAAGACAGCCTGGTGGACCTAGTCCCC TGGTTGAAGATTTTCCCCAACAAAACCCTGGAAAAATTAAAGAGCCATGTTAAAATACGA AATGATCTGCTGAATAAAATACTTGAAAATTACAAGGAGAAATTCCGGAGTGACTCTATC ACCAACATGCTGGACACACTGATGCAAGCCAAGATGAACTCAGATAATGGCAATGCTGGC CCAGATCAAGACTCAGAGCTGCTTTCAGATAACCACATTCTCACCACCATAGGGGACATC TTTGGGGCTGGCGTGGAGACCACCACCTCTGTGGTTAAATGGACCCTGGCCTTCCTGCTG CACAATCCTCAGGTGAAGAAGAAGCTCTACGAGGAGATTGACCAGAATGTGGGTTTCAGC CGCACACCAACTATCAGTGACCGTAACCGTCTCCTCCTGCTGGAGGCCACCATCCGAGAG GTGCTTCGCCTCAGGCCCGTGGCCCCTATGCTCATCCCCCACAAGGCCAACGTTGACTCC AGCATCGGTGAGTTTGCTGTGGACAAGGGCACAGAAGTTATCATCAATCTGTGGGCGCTG CATCACAATGAGAAGGAGTGGCACCAGCCGGATCAGTTCATGCCTGAGCGTTTCTTGAAT CCAGCGGGGACCCAGCTCATCTCACCGTCAGTAAGCTATTTGCCCTTCGGAGCAGGACCT CGCTCCTGTATAGGTGAGATCCTGGCCCGCCAGGAGCTCTTCCTCATCATGGCCTGGCTG CTGCAGAGGTTCGACCTGGAGGTGCCAGATGATGGGCAGCTGCCCTCCCTGGAAGGCATC CCCAAGGTGGTCTTTCTGATCGACTCTTTCAAAGTGAAGATCAAGGTGCGCCAGGCCTGG AGGGAAGCCCAGGCTGAGGGTAGCACCTAAAGGCTGTAACTCACAGCCCCTGTCCACCCT ATGTGGCCCCACAACACAGATTTAGAGATACAACCCCCCACCCTTCTCCGCCATTCTTCC CTACTCCCAACCCACTCTGCCTTCTTTTTCAGCTTGTGGCAATGCCAGTGATGTGCATAA ACAGTTTTTTTTTTTCCAAAAAAAAGTGAAAGGCAGCCTGGGAATGAACATTGTTAGTTC TATCTTGGCCTTCATTGGAGTGATTCTGCTGCTGGTGGATATGTGCATCAATGGGGTAGC TG >OriGene 5' read for NM_000102 unedited
ATTATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGACTGCTGTCT ATCTTGCCTGCCGGCACCCAGCCACCATGTGGGAGCTCGTGGCTCTCTTGCTGCTTACCC TAGCTTATTTGTTTTGGCCCAAGAGAAGGTGCCCTGGTGCCAAGTACCCCAAGAGCCTCC TGTCCCTGCCCCTGGTGGGCAGCCTGCCATTCCTCCCCAGACACGGCCATATGCATAACA ACTTCTTCAAGCTGCAGAAAAAATATGGCCCCATCTATTCGGTTCGTATGGGCACCAAGA CTACAGTGATTGTCGGCCACCACCAGCTGGCCAAGGAGGTGCTTATTAAGAAGGGCAAGG ACTTCTCTGGGCGGCCTCAAATGGCAACTCTAGACATCGCGTCCAACAACCGTAAGGGTA TCGCCTTCGCTGACTCTGGCGCACACTGGCAGCTGCATCGAAGGCTGGCGATGGCCACCT TTGCCCTGTTCAAGGATGGCGATCAGAAGCTGGAGAAGATCATTTGTCAGGAAATCAGTA CATTGTGTGATATGCTGGCCACCCACAACGGACAGTCCATAGACATCTCCTTTCCTGTCT TCGTGGCGGTAACCAATGTCATCTCCTTGATCTGCTTCAATACCTCCTACAAGAATGGGG ACCCTGAGTTGAATGTCATACAGAATTACAATGAAGGCATCATAGACAACCTGAGCAAAG ACAGCCTGGTGGACCTAGTCCCNCTGTTGAAAGATTTCCCCACAAAACCCTGNAAAAATA AAGAGCCATGTAAAATACGAATGATCTGCTGAATAAAATACTGANAATACAGGAGAAANT NCCGATGACTCTTCACCACATGCTGGAACACTGATGCAGCCCAAGATGACTCANATATGG CATGCTGGCCAGATCAGATCAAACTGTTTCGATACCACATCTACACATAGGGACTT >OriGene 3' read for NM_000102 unedited
CTATGGAACGGCGGCCGCAATCTAGGATCGAGTTTTNNNNNNTTTTTTTTTTTTTTTTTT TTTTTTTTTGGGNNCTAAGGACCTTTTATTAAGGAAAAAGTAATTTGAACAGAAACATTT TTAACTTTAAAAAAGTTGCAGAATCATTTTTCAGTCCTCTGATCCTTCACCTTTGCCAGC ATGTAATAGTGGTAATGTAGGAAAAAACAGTGAAGGGAGATACAGCCATTATTAGCGACC AACCTAAAAACAAATTTCAAACACAGTTTTTAAAGACTAGAAATCATTGTAGACAATAAA AGACATTTTTTTAAAAAATTTTTGCAAGGGGTTTTTCTCCATGAAATTAAACTGATACCC CTTTTTCTTTTACTATTTAGGGGCATTAACTGAGTAGTTGTTGCATCTGGGAGGAGCTGA AAAAAACCCTGGGGTCACAGGGTTGCTTTCATACATATTTGGAATAACCAGGACAGACAT ATTGGTTGGGGGGTTTGCTTGGTTGGCAAAATGGGCTGTGGCACAAGCTACGAAGAACTC CAAGAGGGAGAAGATCATCAGCGTGGCTGAAATGCCTTTTCCAGAAAGCACGGCCCAGTA GTCTTGGCCAGCTACCCCATTGATGCACATATCCACCAGCAGCAGAATCACTCCAATGAA GGCCAAGATAGAACTAACAATGTTCATTCCCAGGCTGGCTTTTACTTTTTTTTGGGAAAA AAAAACTGTTTTGCACATCACTGGCATTGCCACAAGCTGAAAAAAAAGGCANAATGGTTN GGGAGTAGGGAAAAATGGCGGGAAAAGGTGGGGGGGTTGTATCTCTAAATTGGTGTGTGG GGCCCCATAGGGTTGACAGGGGCTTGGGAGTACAGCCTTTAGGGCTACCCTCACCTGGGC TTNCCTCAGGCTGGCGCCCTTGACTNACTTTGAAGAACATCACAAAACCCCTGGGGAGCT TCCAGAAGGCACTGCCATAA |
| Restriction Sites | Please inquire |
| ACCN | NM_000102 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000102.2, NP_000093.1 |
| RefSeq Size | 1755 bp |
| RefSeq ORF | 1527 bp |
| Locus ID | 1586 |
| UniProt ID | P05093 |
| Domains | p450 |
| Protein Families | Druggable Genome, P450 |
| Protein Pathways | C21-Steroid hormone metabolism, Metabolic pathways |
| Gene Summary | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008] |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Clinical, Molecular, Functional, and Structural Characterization of CYP17A1 Mutations in Brazilian Patients with 17-Hydroxylase Deficiency.
,null,
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme
,PubMed ID 32215889
[CYP17A1]
|
|
Analysis of novel heterozygous mutations in the CYP11B2 gene causing congenital aldosterone synthase deficiency and literature review
,Miao, H;Yu, Z;Lu, L;Zhu, H;Auchus, RJ;Liu, J;Jiang, J;Pan, H;Gong, F;Chen, S;Lu, Z;,
Steroids
,PubMed ID 31302112
[CYP17A1]
|
|
Functional characterization of the G162R and D216H genetic variants of human CYP17A1
,Capper, CP;Liu, J;McIntosh, LR;Larios, JM;Johnson, MD;Hollenberg, PF;Osawa, Y;Auchus, RJ;Rae, JM;,
J. Steroid Biochem. Mol. Biol.
,PubMed ID 29229304
[CYP17A1]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209042 | CYP17A1 (Myc-DDK-tagged)-Human cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1) |
CNY 5,672.00 |
|
| RC209042L1 | Lenti ORF clone of Human cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), Myc-DDK-tagged |
CNY 8,072.00 |
|
| RC209042L2 | Lenti ORF clone of Human cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), mGFP tagged |
CNY 5,890.00 |
|
| RC209042L3 | Lenti ORF clone of Human cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC209042L4 | Lenti ORF clone of Human cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), mGFP tagged |
CNY 8,072.00 |
|
| RG209042 | CYP17A1 (tGFP-tagged) - Human cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1) |
CNY 7,272.00 |
其它Cytochrome P450 17A1产品
