ECRG4 (NM_032411) Human Untagged Clone
CAT#: SC104814
C2orf40 (untagged)-Human chromosome 2 open reading frame 40 (C2orf40)
CNY 1,200.00
CNY 2,950.00
Cited in 5 publications. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | C2orf40 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC104814 sequence for NM_032411 edited (data generated by NextGen Sequencing)
ATGGCTGCCTCCCCCGCGCGGCCTGCTGTCCTGGCCCTGACCGGGCTGGCGCTGCTCCTG CTCCTGTGCTGGGGCCCAGGTGGCATAAGTGGAAATAAACTCAAGCTGATGCTTCAAAAA CGAGAAGCACCTGTTCCAACTAAGACTAAAGTGGCCGTTGATGAGAATAAAGCCAAAGAA TTCCTTGGCAGCCTGAAGCGCCAGAAGCGGCAGCTGTGGGACCGGACTCGGCCCGAGGTG CAGCAGTGGTACCAGCAGTTTCTCTACATGGGCTTTGACGAAGCGAAATTTGAAGATGAC ATCACCTATTGGCTTAACAGAGATCGAAATGGACATGAATACTATGGCGATTACTACCAA CGTCACTATGATGAAGACTCTGCAATTGGTCCCCGGAGCCCCTACGGCTTTAGGCATGGA GCCAGCGTCAACTACGATGACTACTAA Clone variation with respect to NM_032411.2 >OriGene 5' read for NM_032411 unedited
GCGGATTCGGCACCAGCCGGTTCTCCCTCGCAGCACCTCGAAGTGCGCCCCTCGCCCTCC TGCTCGCGCCCCGCCGCCATGGCTGCCTCCCCCGCGCGGCCTGCTGTCCTGGCCCTGACC GGGCTGGCGCTGCTCCTGCTCCTGTGCTGGGGCCCAGGTGGCATAAGTGGAAATAAACTC AAGCTGATGCTTCAAAAACGAGAAGCACCTGTTCCAACTAAGACTAAAGTGGCCGTTGAT GAGAATAAAGCCAAAGAATTCCTTGGCAGCCTGAAGCGCCAGAAGCGGCAGCTGTGGGAC CGGACTCGGCCCGAGGTGCAGCAGTGGTACCAGCAGTTTCTCTACATGGGCTTTGACGAA GCGAAATTTGAAGATGACATCACCTATTGGCTTAACAGAGATCGAAATGGACATGAATAC TATGGCGATTACTACCAACGTCACTATGATGAAGACTCTGCAATTGGTCCCCGGAGCCCC TACGGCTTTAAGCATGGAACCCAGCGTAACTACGATGACTACTAACCATGACTTGCCACA GGCTGGACCAAAAACAAATACCGATTTTCTTTATGGGTCCCCAAATGGCCTACACTTCTT GGGTTTCTGATCCGCCCCACCCTCACAAATCTTTTGCCCCACCCTGTGGGAACAACAACC ACCCGTCCCCCCCCCTCACTGCAATGGCCCCCCATCGTTCTCAGGTACAGACTTTATTTA ACAACACAACAATACCATCCCTCCAAAA >OriGene 3' read for NM_032411 unedited
CTCTGAACCGCGCCGCATTCTATGATCGGTTTTTTTTTTTTTTTTTTTAACAAAATGCTT TATTTCTATTTTTAAATGAGAGGCATTCCCATGAAATATCAAAAGGCATTTACATGTGTT GTTTTAACTCTTCTTTTTTGATCACACAAAGTAGGTAGAAAAGATCTGCTGAAATAGAGC AAATCAGAAACCAAGTAGTGTAAGGCATTAGGAGATACATGAAGAGAATCGCTATTTGCT TCTTGTACAGCGTGTGGCAAGTCATGGTTAGTAGTCATCGTAGTTGACGCTGGCTCCATG CCTAAAGCCGTAGGGGCTCCGGGGACCAATTGCAGAGTGTTGATGATAGTGACGTCGGAG CAGGCGCGCGCCAGTATGGGTCGCGGTGCCCGACGCTCCCGATCGCTCGTCTGTCCCTGC TGCTTATCGCCCGGTCCACCCCCTTTGCGCTGCCACCCACCCCCCGCGCCTCCCCCCGCC CGCATGCCCGGACTCCTTCGTTCCCTTCTCCCCCCCCCCCCTCATCCCTGCTTCCACTCA TATTTCGTCCCCTCCCCTCCTCCCCACCTTCTTCTTCACCCCTTGGTTAGTTGCCAGTCA CCCCCTGGCCGATCCTCTGCACTTTCGCGTACCTTTTTGGTCCTCACACCCCCCCTTCTT AATCTCCTGCCCTGTTTACATGACCTCCTCATGTGCAATACTCTCTCACTGCCTTCTCTC CGCAAACTATGCCATCCCTATACTATCTCCCCCCCCCCCTTCCCCACTACAGCTGCTTCT CTTCCCATCCTATTCACGACCCACCTCCCCTTACTACCTTCCCTCCTCTTGTATGTATTT GTAGCCGCTTTTTCCCCCACCCCCACCCCCTCCGCTCTTCCCACTATCACACCTTTTCCT AGTCCCCGCTCATACTACACTTACCCTCACCGCTCCTACACCCCACCATCGCCGTGNCCA TACAATTATTTTTCCTTCCCT |
Restriction Sites | NotI-NotI |
ACCN | NM_032411 |
Insert Size | 780 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_032411.1, NP_115787.1 |
RefSeq Size | 772 bp |
RefSeq ORF | 447 bp |
Locus ID | 84417 |
UniProt ID | Q9H1Z8 |
Protein Families | Secreted Protein, Transmembrane |
Gene Summary | Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system (By similarity). ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation (By similarity).[UniProtKB/Swiss-Prot Function] |
Citations (5)
The use of this cDNA Clones has been cited in the following citations: |
---|
ECRG4 regulates neutrophil recruitment and CD44 expression during the inflammatory response to injury
,Dorschner, RA;Lee, J;Cohen, O;Costantini, T;Baird, A;Eliceiri, BP;,
Sci Adv
,PubMed ID 32195341
[ECRG4]
|
Open reading frame mining identifies a TLR4 binding domain in the primary sequence of ECRG4
,Dang, X;Coimbra, R;Mao, L;Podvin, S;Li, X;Yu, H;Costantini, TW;Zeng, X;Larocca, D;Eliceiri, BP;Baird, A;,
Cell. Mol. Life Sci.
,PubMed ID 31190084
[ECRG4]
|
Downregulated ECRG4 is associated with poor prognosis in renal cell cancer and is regulated by promoter DNA methylation
,Luo, L;Wu, J;Xie, J;Xia, L;Qian, X;Cai, Z;Li, Z;,
Tumour Biol.
,PubMed ID 26276361
[ECRG4]
|
Esophageal Cancer Related Gene-4 (ECRG4) Interactions with the Innate Immunity Receptor Complex
,null,
Inflammation research : official journal of the European Histamine Research Society ... [et al.]
,PubMed ID 25511108
[ECRG4]
|
Cell Specific Processing and Release of the Hormone-Like Precursor and Candidate Tumor Suppressor Gene Product, Ecrg4
,null,
Cell and Tissue Research
,PubMed ID 22526622
[ECRG4]
|
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