TBLR1 (TBL1XR1) (AF267864) Human Untagged Clone

Specifications

Product Data
Type	Human Untagged Clone
Tag	Tag Free
Synonyms	C21; DC42; IRA1; MRD41; TBLR1
Vector	pCMV6-XL4
E. coli Selection	Ampicillin (100 ug/mL)
Mammalian Cell Selection	None
Sequence Data	Fully Sequenced ORF (showhide) >NCBI ORF sequence for AF267864, the custom clone sequence may differ by one or more nucleotides ATGCAGCGCTACAATTTTCATTATCTTAAGTACATTGTACATTTCTACAGAACCTGTGATTATTCTCGCA TGATAAGGATGGTACTTGCATATGGTGAATTACTACTGTTGACAGTTTCCGCAGAAATCCTATTTCAGTG GACCAACATTGTGGCATGGCAGCAAATGCCAACATTTTGTGGAATAGCAGCAAATCTACAAGAGACCCTG GTTGGTTTTTCGTTTTGTTTTCTTTGTTTTTTCCCCCTTCTCCTGAATCAGCAGGGATGGAAGGAGGGTA GGGAAGTTATGAATTACTCCTTCCAGTAG 5' Read Nucleotide Sequence (showhide) >OriGene 5' read for AF267864 unedited TCAAATTTTGTATACGACTCACTATAGGCGGCCGCGAAATTCGCACGAGAATACATGAAG GTTTTTTGCTTTTTGACATACGAAAATGTCAAGAGAAAGGCCAAAGATTTGTACTTTTTC ACTTACAAAGCACTCCTTTTTCCCTTAAACTTCTTTCTGTCAAATTAGATTTAATGAGAG AGTACTATTTTTAAGGAGCTATCTGTTTATGTAGAATGATTTTGTTAAGAGTAATGTAAA CTATTATTGAGTAGAGGCCTAAAGAGGACTGTGCATTTTTGCTATTTAAAGGAATCACAA ATGATCATACTTAAGTGAGCAAAAATGACAAGTTTTACTAGCTAAGTAGAGAAATAAATC TCAAATGCAGCGCTACAATTTTCATTATCTTAAGCACATTGTACATTTCTACAGAACCTG TGATTATTCTCGCATGATAAGGATGGTACTTGCATATGGTGAATTACTACTGTTGACAGT TTCCGCAGAAATCCTATTTCAGTGGACCAACATTGTGGCATGGCAGCAAATGCCAACATT TTGTGGAATAGCAGCAAATCTACAAGAGACCCTGGTTGGTTTTTCGTTTTGTTTTCTTTG TTTTTTCCCCCTTCTCCTGAATCAGCAGGGATGGAAGGAGGGTANGGAAGTTACGAATTA CTCCTTCCAATAGTAGCTCTGAAGTGTCACATTTAATATCAGTTTTTTTTTAACATGATT CTAGTTAAATGTAGAAGAGAGAAGAAGAGGAAAGTGTCACTTTTTTTATACACTGATTTA GAAATTTGATGTCTTATATCAGTAGTTCTGAGGTATTGATAGCTTGCCTTATTTCTGCCT TTTACGTGACAGTGTTGAAGCAGGGTGAATAACTANGGCATATATTTTTTTTTTTTGTAA GCTGTTCAATGAGTTTTCTTTGGGATTTCCGGTAAGTTCAGGAAACATCTGCCATGTGNT CTAGNCGGAGTACCTAAC 3' Read Nucleotide Sequence (showhide) >OriGene 3' read for AF267864 unedited NNNNGGGTAAGACTAAGNACCGCGNCCGCATNCTANGATCGAATTTTTTTTTTTTTTTTT AATATCAAAAATATTTTATTCTGGGACTCTTTCAGACTGATTCAAATACAGTTGTCAAAG CAATACAATGCAAAGGGGAACTGCAACAACAACAACAACAAGAAATGTGCCTAGAAAGGA TAAAAGGGTCACTGGGGACAAATCATTGTGATGTGGAACTAAAATACGTCGTAAGTGTAA TTAACATGGTCCAGGACAGCACAGAACATCTACATCAGTCTTCCTTACACAATAATCATG AAAACTGAACAATGAAGTTCTTTAACATGTACAAAAACCTGTCATGGGCTGGTTTACACT TTTACAACAGTTTTAAAGTTAACTGGATAACTAAAGAAATGATGCAGACATTTTAATCCA GTGCTATAGGTAGGCTCACAGAATTAGACCCAAAGGATTTGTAAAAACAAAAATGGAAAC AGTATAGCTACAATGTCAAAGTCAGGAAAGAAGAAAATTTACTTCCGTATTCAAGGATTA CAGAGCTACAAATGCAGTCTGTGTGTTTTTGTTTGTAATGAGATGGATAAGTACATCAGA CTAGATACAACATGCAGAATGTTTTCCTGAACTTATCCGGAAATTCCAAAGAAAACATCA TGAAACAGCTTACAAAAAAAAAAAAATATATGCCCTAGTTATTCACCCTGCTTCAACACT GTCAACGTAAAGGCAGAAATAAAGCAAGCTATCAATACCTCAGAACTACTGATATAAGAC ATCAAATTTCTAAATCAGTGTATTAAAAAAGTGAACACTTCCTCTTTTCTTCTCTCTTCT ACATTTAACTAGAATCATGTTTAAAAAAACTGATAATTAATGTGACACTTTCAA
Restriction Sites	NotI-NotI
ACCN	AF267864
Insert Size	1410 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note	Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq	AF267864.1, AAG44733.1
RefSeq Size	1632 bp
RefSeq ORF	1632 bp
Locus ID	79718
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Wnt signaling pathway
Gene Summary	This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. [provided by RefSeq, Mar 2016]

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