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p18 INK4c (CDKN2C) (NM_001262) Human Untagged Clone
CAT＃: SC107906
CDKN2C (untagged)-Human cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 1
CNY 2,400.00
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | INK4C; p18; p18-INK4C |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC107906 sequence for NM_001262 edited (data generated by NextGen Sequencing)
ATGGCCGAGCCTTGGGGGAACGAGTTGGCGTCCGCAGCTGCCAGGGGGGACCTAGAGCAA CTTACTAGTTTGTTGCAAAATAATGTAAACGTCAATGCACAAAATGGATTTGGAAGGACT GCGCTGCAGGTTATGAAACTTGGAAATCCCGAGATTGCCAGGAGACTGCTACTTAGAGGT GCTAATCCCGATTTGAAAGACCGAACTGGTTTCGCTGTCATTCATGATGCGGCCAGAGCA GGTTTCCTGGACACTTTACAGACTTTGCTGGAGTTTCAAGCTGATGTTAACATCGAGGAT AATGAAGGGAACCTGCCCTTGCACTTGGCTGCCAAAGAAGGCCACCTCCGGGTGGTGGAG TTCCTGGTGAAGCACACGGCCAGCAATGTGGGGCATCGGAACCATAAGGGGGACACCGCC TGTGATTTGGCCAGGCTCTATGGGAGGAATGAGGTTGTTAGCCTGATGCAGGCAAACGGG GCTGGGGGAGCCACAAATCTTCAATAA Clone variation with respect to NM_001262.2 >OriGene 5' read for NM_001262 unedited
NNNNGGGAGANCNNCNNACCCTCCCCCCCCCCCGGTTCAGAATTTGTNATACGACTCACT ATAGGCGGCCGCGCGCATCACTCTCCTTCCTCGGGCTGCCGGGAGTCCCGGGACCTGGCG GGGCCGGCATGACGGGCTTCTCGGGGGCCCGCCGCACGCCCGGCAGCCTCCGGAGACGCG CGCCGAGCCCGGCTCCCACGGCCTCTGAGGCTCGGCGGGGCTGCGGCTGCCTGGCGGGCG GGCTCCGGAGCTTTCCTGAGCGGCATTAGCCCACGGCTTGGCCCGGACGCGACCAAAGGC TCTTCTGGAGAAGCCCAGAGCACTGGGCAATCGTTACGACCTGTAACTTGAGGGCCACCG AACTGCTACTCCCGTTCGCCTTTGGCGATCATCTTTTAACCCTCCGGAGCACGTCAGCAT CCAGCCACCGCGGCGCTCTCCCAGCAGCGGAGGACCCAGGACTATCCCTTCGGCGAGACG GATGGAAACCGAGCCCCCTGGAGGACCTGCCCCTGCAGTTCTGCCTCACACGGCTCAAGT CACCACCGTGAACAAGGGACCCTAAAGAATGGCCGAGCCTTGGGGGAACGAGTTGGCGTC CGCAGCTGCCAGGGGGGACCTAGAGCAACTTACTANGTTTGGTGCANAATAATGTAAACG TCAATGCACAAAATGGATNTGGAAGGACTGCGCTGCAGGTTATGAAACTTGGAAATCCCG AGATTGCCAGGAGACTGCTACTTTANAGGTGCTAAATCCCGATTTGAAAGACCGAACTGG GTTTCGCTGTCATTCATGATGCGGGCANAGCAGGTTTCCCTGGACACTTTACAGACCTTG CTGGGAGTTTCAAGCTGATGGTAACCTCGAGGATAATGGAAGGGAACCTGCCCTTGCACT TGGCTGCCAAAGAAGCCACTCCGGCTGGGGGGGAGGTCCCTGTGGAACC >OriGene 3' read for NM_001262 unedited
NNGGGTTTACTATGNACCGCGCCGCAATCTANGATCGGTTTTTTTTTTTTTTTTTTCCTG TTTTGAAGTGTTTTAATTAGACAAAAGCATCAGGACAAACCATTTTAAAAACAAAGTCTT CAACTTGGGTGTTGAGATTGGCAAAAGGGGAAGCAAGGGAAAAGCCAAGGAAAGATAAAA TATTCAGAAGAAAGTCAAAGTTATCTGCAATTACATGTTAGAACAGATTTTGCAGGTTAA AAAGATGTTGCTTAAATATATTCATAAGCCTGTTGTAAGATTTTCACTTATGCAGTTTCA GAAAATTTAGCTGCTTAACATATGACAGAACTGTATTTTAACAAATGACATTAAAAGTCA GGAGAGCTACTCAGTTAATTGATAAAGTAGAGGCAACGTGGGGGAGCCCTCCCCACGTTT ATTGAAGATTTGTGGCTCCCCCAGCCCCGTTTGCCTGCATCAGGCTAACAACCTCATTCC TCCCATAGAGCCTGGCCAAATCACAGGCGGTGTCCCCCTTATGGTTCCGATGCCCCACAT TGCTGGCCGTGTGCTTCACCAGGAACTCCACCACCCGGAGGTGGCCTTCTTTGGCAGCCA AGTGCAAGGGCAGGTTCCCTTCATTATCCTCGATGTTAACATCAGCTTGAAACTCCAGCA AAGTCTGTAAAGTGTCCAGGAAACCTGCTCTGGCCGCATCATGAATGACAGCGAAACCAG TTCGGTCTTTCAAATCGGGATTAGCACCTCTAAGTAGCAGTCTCCTGGGCATCTCGGGAT TTCCAAGTTTTATAACCTGCAGCGCAGTCCTTCCAAATCCATTTTGTGCATTGACGTTTA CATTATTTTGCAACAAACTAGTAAGTTGCTCCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001262 |
| Insert Size | 1500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001262.2, NP_001253.1 |
| RefSeq Size | 2104 bp |
| RefSeq ORF | 507 bp |
| Locus ID | 1031 |
| UniProt ID | P42773 |
| Protein Families | Druggable Genome |
| Protein Pathways | Cell cycle |
| Gene Summary | The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) contains a different 5' UTR region, and encodes an identical protein, when compared to variant 2. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213083 | CDKN2C (Myc-DDK-tagged)-Human cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 1 |
CNY 2,400.00 |
|
| RC213083L1 | Lenti ORF clone of Human cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 1, Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC213083L2 | Lenti ORF clone of Human cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC213083L3 | Lenti ORF clone of Human cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC213083L4 | Lenti ORF clone of Human cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 1, mGFP tagged |
CNY 4,800.00 |
|
| RG213083 | CDKN2C (tGFP-tagged) - Human cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) (CDKN2C), transcript variant 1 |
CNY 4,000.00 |
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