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Glutathione Reductase (GSR) (NM_000637) Human Untagged Clone
CAT＃: SC108586
GSR (untagged)-Human glutathione reductase (GSR), transcript variant 1
CNY 11,048.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GR; GSRD; HEL-75; HEL-S-122m |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_000637, the custom clone sequence may differ by one or more nucleotides
ATGGCCCTGCTGCCCCGAGCCCTGAGCGCCGGCGCGGGACCGAGCTGGCGGCGGGCGGCGCGCGCCTTCC GAGGCTTCCTGCTGCTTCTGCCCGAGCCCGCGGCCCTCACGCGCGCCCTCTCCCGTGCCATGGCCTGCAG GCAGGAGCCGCAGCCGCAGGGCCCGCCGCCCGCTGCTGGCGCCGTGGCCTCCTATGACTACCTGGTGATC GGGGGCGGCTCGGGCGGGCTGGCCAGCGCGCGCAGGGCGGCCGAGCTGGGTGCCAGGGCCGCCGTGGTGG AGAGCCACAAGCTGGGTGGCACTTGCGTGAATGTTGGATGTGTACCCAAAAAGGTAATGTGGAACACAGC TGTCCACTCTGAATTCATGCATGATCATGCTGATTATGGCTTTCCAAGTTGTGAGGGTAAATTCAATTGG CGTGTTATTAAGGAAAAGCGGGATGCCTATGTGAGCCGCCTGAATGCCATCTATCAAAACAATCTCACCA AGTCCCATATAGAAATCATCCGTGGCCATGCAGCCTTCACGAGTGATCCCAAGCCCACAATAGAGGTCAG TGGGAAAAAGTACACCGCCCCACACATCCTGATCGCCACAGGTGGTATGCCCTCCACCCCTCATGAGAGC CAGATCCCCGGTGCCAGCTTAGGAATAACCAGCGATGGATTTTTTCAGCTGGAAGAATTGCCCGGCCGCA GCGTCATTGTTGGTGCAGGTTACATTGCTGTGGAGATGGCAGGGATCCTGTCAGCCCTGGGTTCTAAGAC ATCACTGATGATACGGCATGATAAGGTACTTAGAAGTTTTGATTCAATGATCAGCACCAACTGCACGGAG GAGCTGGAGAACGCTGGCGTGGAGGTGCTGAAGTTCTCCCAGGTCAAGGAGGTTAAAAAGACTTTGTCGG GCTTGGAAGTCAGCATGGTTACTGCAGTTCCCGGTAGGCTACCAGTCATGACCATGATTCCAGATGTTGA CTGCCTGCTCTGGGCCATTGGGCGGGTCCCGAATACCAAGGACCTGAGTTTAAACAAACTGGGGATTCAA ACCGATGACAAGGGTCATATCATCGTAGACGAATTCCAGAATACCAACGTCAAAGGCATCTATGCAGTTG GGGATGTATGTGGAAAAGCTCTTCTTACTCCAGTTGCAATAGCTGCTGGCCGAAAACTTGCCCATCGACT TTTTGAATATAAGGAAGATTCCAAATTAGATTATAACAACATCCCAACTGTGGTCTTCAGCCACCCCCCT ATTGGGACAGTGGGACTCACGGAAGATGAAGCCATTCATAAATATGGAATAGAAAATGTGAAGACCTATT CAACGAGCTTTACCCCGATGTATCACGCAGTTACCAAAAGGAAAACAAAATGTGTGATGAAAATGGTCTG TGCTAACAAGGAAGAAAAGGTGGTTGGGATCCATATGCAGGGACTTGGGTGTGATGAAATGCTGCAGGGT TTTGCTGTTGCAGTGAAGATGGGAGCAACGAAGGCAGACTTTGACAACACAGTCGCCATTCACCCTACCT CTTCAGAAGAGCTGGTCACACTTCGTTGA >OriGene 5' read for NM_000637 unedited
GATTTTGTAATACGACTTACTATAGGGCGGCCGCGAATTCGGCACCAGGCGGCGCGCGCC TTCCGAGGCTTCCTGCTGCTTCTGCCCGAGCCCGCGGCCCTCACGCGCGCCCTCTCCCGT GCCATGGCCTGCAGGCAGGAGCCGCAGCCGCAGGGCCCGCCGCCCGCTGCTGGCGCCGTG GCCTCCTATGACTACCTGGTGATCGGGGGCGGCTCGGGCGGGCTGGCCAGCGCGCGCAGG GCGGCCGAGCTGGGTGCCAGGGCCGCCGTGGTGGAGAGCCACAAGCTGGGTGGCACTTGC GTGAATGTTGGATGTGTACCCAAAAAGGTAATGTGGAACACAGCTGTCCACTCTGAATTC ATGCATGATCATGCTGATTATGGCTTTCCAAGTTGTGAGGGTAAATTCAATTGGCGTGTT ATTAAGGAAAAGCGGGATGCCTATGTGAGCCGCCTGAATGCCATCTATCAAAACAATCTC ACCAAGTCCCATATAGAAATCATCCGTGGCCATGCAGCCTTCACGAGTGATCCCAAGCCC ACAATAGAGGTCAGTGGGAAAAAGTACACCGCCCCACACATCCTGATCGCCACAGGTGGT ATGCCCTCCACCCCTCATGAGAGCCAGATCCCCGGTGCCAGCTTAGGAATAACCAGCGAT GGATTTTTTCAGCTGGAAGAATTGCCCGGCCGCAGCGTCATTGTTGGTGCANGTTACATT GCTGTGGAGATGGCAGGNATCCTGTCAGCCCTGNGTTCTAAGACATCACTGATGATACCG CATGATAAGGTACTTTAGAGTTTTGATTCANTGATCAGCACCAACTGCACGNGAGAGCTG GAGAACGCNNTGCGTGNAGTGCTGAAGTTCTNCCAGGTCAAGGAGGTAAAAAAGACTTGT CGGNCTTNGAAGTCANCATGGNTACTGCAGTTTCCGGGTAGCTACCAGTCATGACCCATG ATCCCAGTGTTGACTGCCTGCTCTGGGCCATTGGCGGNTC >OriGene 3' read for NM_000637 unedited
GCCCATTTAGNACGCGCCGCATTTANGATCGGTTTTTTTTTTTTTTTTTTGTAAGTCAAT GTGATTATTTGTTTCATTTCAGAAGATCTATGGGTCCCACTGCCCGCCACACGTGTCTCC TGGTTCTCAACGAAGTGTGACCAGCTCTTCTGAAGAGGTAGGGTGAATGGCGACTGTGTT GTCAAAGTCTGCCTTCGTTGCTCCCATCTTCACTGCAACAGCAAAACCCTGCAGCATTTC ATCACACCCAAGTCCCTGCATATGGATCCCAACCACCTTTTCTTCCTTGTTAGCACAGAC CATTTTCATCACACATTTTGTTTTCCTTTTGGTAACTGCGTGATACATCGGGGTAAAGCT CGTTGAATAGGTCTTCACATTTTCTATTCCATATTTATGAATGGCTTCATCTTCCGTGAG TCCCACTGTCCCAATAGGGGGGTGGCTGAAGACCACAGTTGGGATGTTGTTATAATCTAA TTTGGAATCTTCCTTATATTCAAAAAGTCGATGGGCAAGTTTTCGGCCAGCAGCTATTGC AACTGGAGTAAGAAGAGCTTTTCCACATACATCCCCAACTGCATAGATGCCTTTGACGTT GGTATTCTGGAATTCGTCTACGATGATATGACCCTTGTCATCGGTTTGAATCCCCAGTTT GTTTAAACTCANGTCCTTGGTATTCGGGACCCGCCCAATGGCCCAGAGCANGCAGTCAAC ATCTGGAATCATGGTCATGACTGGTAGCCTACCGGGAACTGCAGTAACCATGCTGACTTC CNAGCCCGACAAAAGTCTTTTAAACTCCTTGACCTGGGAGAACTTCAGCACCTCCACGCC AGCGTTCTCCAGCTCCTNCGTGCAGTTGGTGCTGATCATTGAAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000637 |
| Insert Size | 1900 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_000637.1, NP_000628.1 |
| RefSeq Size | 3174 bp |
| RefSeq ORF | 3174 bp |
| Locus ID | 2936 |
| UniProt ID | P00390 |
| Domains | pyr_redox, pyr_redox_dim |
| Protein Families | Druggable Genome |
| Protein Pathways | Glutathione metabolism |
| Gene Summary | This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010] Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209652 | GSR (Myc-DDK-tagged)-Human glutathione reductase (GSR), transcript variant 1 |
CNY 5,832.00 |
|
| RC209652L3 | Lenti ORF clone of Human glutathione reductase (GSR), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC209652L4 | Lenti ORF clone of Human glutathione reductase (GSR), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG209652 | GSR (tGFP-tagged) - Human glutathione reductase (GSR), transcript variant 1 |
CNY 4,370.00 |
|
| SC317883 | GSR (untagged)-Human glutathione reductase (GSR), transcript variant 1 |
CNY 7,220.00 |
|
| SC320532 | GSR (untagged)-Human glutathione reductase (GSR), transcript variant 1 |
CNY 5,840.00 |
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