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ITM2B (NM_021999) Human Untagged Clone
CAT＃: SC108808
ITM2B (untagged)-Human integral membrane protein 2B (ITM2B)
CNY 2,400.00
CNY 2,950.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ABRI; BRI; BRI2; BRICD2B; E3-16; E25B; FBD; imBRI2; RDGCA |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC108808 sequence for NM_021999 edited (data generated by NextGen Sequencing)
ATGGTGAAGGTGACGTTCAACTCCGCTCTGGCCCAGAAGGAGGCCAAGAAGGACGAGCCC AAGAGCGGCGAGGAGGCGCTCATCATCCCCCCCGACGCCGTCGCGGTGGACTGCAAGGAC CCAGATGATGTGGTACCAGTTGGCCAAAGAAGAGCCTGGTGTTGGTGCATGTGCTTTGGA CTAGCATTTATGCTTGCAGGTGTTATTCTAGGAGGAGCATACTTGTACAAATATTTTGCA CTTCAACCAGATGACGTGTACTACTGTGGAATAAAGTACATCAAAGATGATGTCATCTTA AATGAGCCCTCTGCAGATGCCCCAGCTGCTCTCTACCAGACAATTGAAGAAAATATTAAA ATCTTTGAAGAAGAAGAAGTTGAATTTATCAGTGTGCCTGTCCCAGAGTTTGCAGATAGT GATCCTGCCAACATTGTTCATGACTTTAACAAGAAACTTACAGCCTATTTAGATCTTAAC CTGGATAAGTGCTATGTGATCCCTCTGAACACTTCCATTGTTATGCCACCCAGAAACCTA CTGGAGTTACTTATTAACATCAAGGCTGGAACCTATTTGCCTCAGTCCTATCTGATTCAT GAGCACATGGTTATTACTGATCGCATTGAAAACATTGATCACCTGGGTTTCTTTATTTAT CGACTGTGTCATGACAAGGAAACTTACAAACTGCAACGCAGAGAAACTATTAAAGGTATT CAGAAACGTGAAGCCAGCAATTGTTTCGCAATTCGGCATTTTGAAAACAAATTTGCCGTG GAAACTTTAATTTGTTCTTGA Clone variation with respect to NM_021999.4 >OriGene 5' read for NM_021999 unedited
TTGTATACGACTCACTATAGGGCGGCCGCGATTCGGCACGAGGCCGCCGCGGAGCTTCCC GAACCTCTTCAGCCGCCCGGAGCCGCTCCCGGAGCCCGGCCGTAGAGGCTGCAATCGCAG CCGGGAGCCCGCAGCCCGCGCCCCGAGCCCGCCGCCGCCCTTCGAGGGCGCCCCAGGCCG CGCCATGGTGAAGGTGACGTTCAACTCCGCTCTGGCCCAGAAGGAGGCCAAGAAGGACGA GCCCAAGAGCGGCGAGGAGGCGCTCATCATCCCCCCCGACGCCGTCGCGGTGGACTGCAA GGACCCAGATGATGTGGTACCAGTTGGCCAAAGAAGAGCCTGGTGTTGGTGCATGTGCTT TGGACTAGCATTTATGCTTGCAGGTGTTATTCTAGGAGGAGCATACTTGTACAAATATTT TGCACTTCAACCAGATGACGTGTACTACTGTGGAATAAAGTACATCAAAGATGATGTCAT CTTAAATGAGCCCTCTGCAGATGCCCCAGCTGCTCTCTACCAGACAATTGAAGAAAATAT TAAAATCTTTGAAGAAGAAGAAGTTGAATTTTTCAGTGTGCCTGTCCCAGAGTTTGCAGA TAGTGATCCTGCCAACATTGTTCATGACTTTAACAAGAAACTTACAGCCTATTTAGATCT TAACCTGNATAAGTGCTNATGTGATCCCTCTGAACACTTNCATTGTTATGCCACCCAGAA ACCTACTGGGAGNTACTTATTAACATCAAGGGCTGGAAACCTATTTGCCTCAGTCCTATC TGATTCATGAGCACATGGTTATTACTGGATCGCATTGAAACATTGATCACNTGGGGTTTC TTTTATTTATCGACTGGTGTCATGACAAGGAAACTTACAAACTGGCACGCANNAGAACTT T >OriGene 3' read for NM_021999 unedited
NNTTTTAGCTATGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTCT AGTTAAACAACTTTGTGATATTTATATTCCATTGCACAGATATGGGTTATACAAATTAGT AACACAAGTTATTTCTTAAATTCCAAACATTTTCTAAAATATTATTACAGCAGATGCCTA GGATATTAAAACATAAAGGTGGAAATCATTCTCTAAATAGTTAAATATATTTGACACTGA AAATACTGCACATTTTAATTAGAGGAAAATTAAAATGTGTGCTCAAATGCACTAACAAAC TAGGTAGCAGGGCAACTAACAACTACAAATAAGTCACTGTGGTCCATTTTTACGTATGCA TATATATGATTATTCTCTAGATAATCCGTCTTCTTGAAAATGCTAATAAAACATAAAAAT CCAGATAAATGATTTAAAGAAATTGTAATTCTTCCTACTACCTAAGGTGACATGTACTAT TATCTATGACTTCATACAGTTACTAATTCAAATATAAAAGACACCACACTTCGAAAGAAA AAAATTTTAAGGTAATGGTTCTAATTGAATTAATGAGATGAAAAGATAGTAAAGCCCTGT TTGCTACTTACATGAAAGAAGACTTTAAAAAAATATCACTGCACANAATGTAAAGGGTGG GGTTATGCTGAGATACTAATTTCCCTCAATAATGTTTTTCTTGACTGTTCAAGAACAAAT TAAAGTTCCACGGCATATTTGTTTTCAAATGCCCGAATGCGAAACAATTGTTGGCTTTAC GTTTCTGAATACCCTTAATAGTTCTTTGCGGTGCAATTTGTAAGTTCCCCTGCCTGACCA GCNCGATAATAAAGAACCCAGGTGAACAAGGTTTCATGCCAACATAAAACCATGGGCCCA A |
| Restriction Sites | NotI-NotI |
| ACCN | NM_021999 |
| Insert Size | 1500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_021999.2, NP_068839.1 |
| RefSeq Size | 1896 bp |
| RefSeq ORF | 801 bp |
| Locus ID | 9445 |
| UniProt ID | Q9Y287 |
| Domains | BRICHOS |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. [provided by RefSeq, Oct 2009] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202377 | ITM2B (Myc-DDK-tagged)-Human integral membrane protein 2B (ITM2B) |
CNY 2,400.00 |
|
| RC202377L1 | Lenti ORF clone of Human integral membrane protein 2B (ITM2B), Myc-DDK-tagged |
CNY 4,800.00 |
|
| RC202377L2 | Lenti ORF clone of Human integral membrane protein 2B (ITM2B), mGFP tagged |
CNY 5,890.00 |
|
| RC202377L3 | Lenti ORF clone of Human integral membrane protein 2B (ITM2B), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202377L4 | Lenti ORF clone of Human integral membrane protein 2B (ITM2B), mGFP tagged |
CNY 5,890.00 |
|
| RG202377 | ITM2B (tGFP-tagged) - Human integral membrane protein 2B (ITM2B) |
CNY 4,000.00 |
|
| SC322363 | ITM2B (untagged)-Human integral membrane protein 2B (ITM2B) |
CNY 2,400.00 |
