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CD97 (ADGRE5) (NM_001784) Human Untagged Clone
CAT＃: SC109040
CD97 (untagged)-Human CD97 molecule (CD97), transcript variant 2
CNY 5,440.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD97; TM7LN1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>SC109040 representing NM_001784.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCGGCCGCGAATTCGGCACGAGGAGACGGGACAGCCCTGTCCCACTCACTCTTTCCCCTGCCGCTCCTG CCGGCAGCTCCAACCATGGGAGGCCGCGTCTTTCTCGCATTCTGTGTCTGGCTGACTCTGCCGGGAGCT GAAACCCAGGACTCCAGGGGCTGTGCCCGGTGGTGCCCTCAGAACTCCTCGTGTGTCAATGCCACCGCC TGTCGCTGCAATCCAGGGTTCAGCTCTTTTTCTGAGATCATCACCACCCCGACGGAGACTTGTGACGAC ATCAACGAGTGTGCAACACCGTCGAAAGTGTCATGCGGAAAATTCTCGGACTGCTGGAACACAGAGGGG AGCTACGACTGCGTGTGCAGCCCGGGATATGAGCCTGTTTCTGGGGCAAAAACATTCAAGAATGAGAGC GAGAACACCTGTCAAGATGTGGACGAGTGCAGCTCCGGGCAGCATCAGTGTGACAGCTCCACCGTCTGC TTCAACACCGTGGGTTCATACAGCTGCCGCTGCCGCCCAGGCTGGAAGCCCAGACACGGAATCCCGAAT AACCAAAAGGACACTGTCTGTGAAGATATGACTTTCTCCACCTGGACCCCGCCCCCTGGAGTCCACAGC CAGACGCTTTCCCGATTCTTCGACAAAGTCCAGGACCTGGGCAGAGACTCCAAGACAAGCTCAGCCGAG GTCACCATCCAGAATGTCATCAAATTGGTGGATGAACTGATGGAAGCTCCTGGAGACGTAGAGGCCCTG GCGCCACCTGTCCGGCACCTCATAGCCACCCAGCTGCTCTCAAACCTTGAAGATATCATGAGGATCCTG GCCAAGAGCCTGCCTAAAGGCCCCTTCACCTACATTTCCCCTTCGAACACAGAGCTGACCCTGATGATC CAGGAGCGGGGGGACAAGAACGTCACTATGGGTCAGAGCAGCGCACGCATGAAGCTGAATTGGGCTGTG GCAGCTGGAGCCGAGGATCCAGGCCCCGCCGTGGCGGGCATCCTCTCCATCCAGAACATGACGACATTG CTGGCCAATGCCTCCTTGAACCTGCATTCCAAGAAGCAAGCCGAACTGGAGGAGATATATGAAAGCAGC ATCCGTGGTGTCCAACTCAGACGCCTCTCTGCCGTCAACTCCATCTTTCTGAGCCACAACAACACCAAG GAACTCAACTCCCCCATCCTTTTCGCCTTCTCCCACCTTGAGTCCTCCGATGGGGAGGCGGGAAGAGAC CCTCCTGCCAAGGACGTGATGCCTGGGCCACGGCAGGAGCTGCTCTGTGCCTTCTGGAAGAGTGACAGC GACAGGGGAGGGCACTGGGCCACCGAGGGCTGCCAGGTGCTGGGCAGCAAGAACGGCAGCACCACCTGC CAATGCAGCCACCTGAGCAGCTTTGCGATCCTTATGGCTCATTATGACGTGGAGGACTGGAAGCTGACC CTGATCACCAGGGTGGGACTGGCGCTGTCACTCTTCTGCCTGCTGCTGTGCATCCTCACTTTCCTGCTG GTGCGGCCCATCCAGGGCTCGCGCACCACCATACACCTGCACCTCTGCATCTGCCTCTTCGTGGGCTCC ACCATCTTCCTGGCCGGCATCGAGAACGAAGGCGGCCAGGTGGGGCTGCGCTGCCGCCTGGTGGCCGGG CTGCTGCACTACTGTTTCCTGGCCGCCTTCTGCTGGATGAGCCTCGAAGGCCTGGAGCTCTACTTTCTT GTGGTGCGCGTGTTCCAAGGCCAGGGCCTGAGTACGCGCTGGCTCTGCCTGATCGGCTATGGCGTGCCC CTGCTCATCGTGGGCGTCTCGGCTGCCATCTACAGCAAGGGCTACGGCCGCCCCAGATACTGCTGGTTG GACTTTGAGCAGGGCTTCCTCTGGAGCTTCTTGGGACCTGTGACCTTCATCATTTTGTGCAATGCTGTC ATTTTCGTGACTACCGTCTGGAAGCTCACTCAGAAGTTTTCTGAAATCAATCCAGACATGAAGAAATTA AAGAAGGCGAGGGCGCTGACCATCACGGCCATCGCGCAGCTCTTCCTGTTGGGCTGCACCTGGGTCTTT GGCCTGTTCATCTTCGACGATCGGAGCTTGGTGCTGACCTATGTGTTTACCATCCTCAACTGCCTGCAG GGCGCCTTCCTCTACCTGCTGCACTGCCTGCTCAACAAGAAGGTTCGGGAAGAATACCGGAAGTGGGCC TGCCTAGTTGCTGGGGGGAGCAAGTACTCAGAATTCACCTCCACCACGTCTGGCACTGGCCACAATCAG ACCCGGGCCCTCAGGGCATCAGAGTCCGGCACATGAAGGCGCATGGTTCTGGACGGCCCAGCAGCTCCT GTGGCCACAGCAGCTTTGTACACGAAGACCATCCATCCTCCCTTCGTCCACCACTCTACTCCCTCCACC CTCCCTCCCTGATCCCGTGTGCCACCAGGAGGGAGTGGCAGCTATAGTCTGGCACCAAAGTCCAGGACA CCCAGTGGGGTGGAGTCGGAGCCACTGGTCCTGCTGCTGGCTGCCTCTCTGCTCCACCTTGTGACCCAG GGTGGGGACAGGGGCTGGCCCAGGGCTGCAATGCAGCATGTTGCCCTGGCACCTGTGGCCAGTACTCGG GACAGACTAAGGGCGCTTGTCCCATCCTGGACTTTTCCTCTCATGTCTTTGCTGCAGAACTGAAGAGAC TAGGCGCTGGGGCTCAGCTTCCCTCTTAAGCTAAGACTGATGTCAGAGGCCCCATGGCGAGGCCCCTTG GGGCCACTGCCTGAGGCTCACGGTACAGAGGCCTGCCCTGCCTGGCCGGGCAGGAGGTTCTCACTGTTG TGAAGGTTGTAGACGTTGTGTAATGTGTTTTTATCTGTTAAAATTTTTCAGTGTTGACACTTAAAATTA AACACATGCATACAGAAAAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCGC >OriGene 5' read for NM_001784 unedited
GAACCGTCAAATTTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGAGACG GGACAGCCCTGTCCCACTCACTCTTTCCCCTGCCGCTCCTGCCGGCAGCTCCAACCATGG GAGGCCGCGTCTTTCTCGCATTCTGTGTCTGGCTGACTCTGCCGGGAGCTGAAACCCAGG ACTCCAGGGGCTGTGCCCGGTGGTGCCCTCAGAACTCCTCGTGTGTCAATGCCACCGCCT GTCGCTGCAATCCAGGGTTCAGCTCTTTTTCTGAGATCATCACCACCCCGACGGAGACTT GTGACGACATCAACGAGTGTGACACACCGTCGAAAGTGTCATGCGGAAAATTCTCGGACT GCTGGAACACAGAGGGGAGCTACGACTGCGTGTGCAGCCCGGGATATGAGCCTGTTTCTG GGGCAAAAACATTCAAGAATGAGAGCGAGAACACCTGTCAAGATGTGGACGAGTGCAGCT CCGGGCAGCATCAGTGTGACAGCTCCACCGTCTGCTTCAACACCGTGGGTTCATACAGCT GCCGCTGCCGCCCAGGCTGGAAGCCCAGACACGGAATCCCGAATAACCAAAAGGACACTG TCTGTGAAGATATGACTTTCTCCACCTGGACCCCGCCCCCTGGAGTCCACAGCCAGACGC TTTCCCGATTCTTCGACAAAGTCCAGGACCTGGGCAGAGACTCCAAGACAAGCTCAGCCG AGGTCACCATCCAGAATGGTCATCAATTGGGTGGATGAACTGATGGAAGCTCCTGGAAAC GTATAGGCCCTGGCGCCACCTGTCCGGCACCTTATAGCCCCCAAGCTGCTCTCAAACCTT TGAGAAATCATGAGGATCCCGGCCAAGAACCTGCTTAAGGCCCCCTCCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001784 |
| Insert Size | 2954 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001784.3 |
| RefSeq Size | 2968 bp |
| RefSeq ORF | 2954 bp |
| Locus ID | 976 |
| UniProt ID | P48960 |
| Domains | GPS, 7tm_2, EGF_CA, EGF, EGF |
| Protein Families | Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, GPCR, Secreted Protein, Transmembrane |
| MW | 107.8 kDa |
| Gene Summary | This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19. [provided by RefSeq, Jun 2011] Transcript Variant: This variant (2) lacks two consecutive exons in the coding region but maintains the reading frame, compared to variant 1. The encoded isoform (2, also known as CD97(EGF 1,2,5)) is shorter than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A-to-I-edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis
,Xu, X;Wang, Y;Mojumdar, K;Zhou, Z;Jeong, KJ;Mangala, LS;Yu, S;Tsang, YH;Rodriguez-Aguayo, C;Lu, Y;Lopez-Berestein, G;Sood, AK;Mills, GB;Liang, H;,
J. Clin. Invest.
,PubMed ID 31682236
[ADGRE5]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202001 | CD97 (Myc-DDK-tagged)-Human CD97 molecule (CD97), transcript variant 2 |
CNY 5,432.00 |
|
| RC202001L1 | Lenti ORF clone of Human CD97 molecule (CD97), transcript variant 2, Myc-DDK-tagged |
CNY 7,832.00 |
|
| RC202001L2 | Lenti ORF clone of Human CD97 molecule (CD97), transcript variant 2, mGFP tagged |
CNY 7,700.00 |
|
| RC202001L3 | Lenti ORF clone of Human CD97 molecule (CD97), transcript variant 2, Myc-DDK-tagged |
CNY 7,700.00 |
|
| RC202001L4 | Lenti ORF clone of Human CD97 molecule (CD97), transcript variant 2, mGFP tagged |
CNY 7,832.00 |
|
| RG202001 | CD97 (tGFP-tagged) - Human CD97 molecule (CD97), transcript variant 2 |
CNY 7,032.00 |
|
| SC109039 | CD97 (untagged)-ORIGENE UNIQUE VARIANT 1 of Human CD97 molecule (CD97) |
CNY 5,440.00 |
