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Transportin 1 (TNPO1) (NM_153188) Human Untagged Clone
CAT＃: SC109373
TNPO1 (untagged)-Human transportin 1 (TNPO1), transcript variant 2
CNY 6,528.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IPO2; KPNB2; MIP; MIP1; TRN |
| Vector | pCMV6-XL6 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC109373 sequence for NM_153188 edited (data generated by NextGen Sequencing)
ATGGAGTATGAGTGGAAACCTGACGAGCAAGGGCTTCAGCAAATCCTGCAGCTGTTGAAG GAGTCCCAGTCCCCAGACACCACCATCCAGAGAACCGTGCAACAAAAACTGGAACAACTT AATCAGTATCCAGACTTTAACAACTACTTGATTTTTGTTCTTACAAAATTAAAATCTGAA GATGAACCCACAAGATCATTGAGTGGTCTTATCTTGAAGAATAATGTGAAAGCACACTTT CAGAACTTCCCAAATGGTGTAACAGACTTTATTAAAAGTGAATGTTTAAATAATATTGGT GACTCCTCTCCTCTGATTAGAGCCACTGTTGGTATTTTGATCACAACTATAGCCTCCAAG GGAGAATTGCAGAATTGGCCTGACCTCTTACCAAAACTCTGTAGCCTGTTGGATTCTGAA GATTATAATACCTGTGAGGGAGCATTTGGTGCCCTTCAGAAGATTTGTGAAGATTCTGCT GAGATTTTAGACAGTGATGTTTTAGATCGTCCTCTCAACATCATGATTCCCAAATTTTTA CAGTTCTTCAAGCATAGTAGTCCAAAAATAAGGTCTCACGCTGTTGCATGTGTCAATCAG TTTATCATCAGTAGGACTCAAGCTCTAATGTTGCACATTGATTCTTTTATTGAGAATCTC TTTGCATTAGCTGGTGATGAAGAACCAGAGGTACGGAAAAATGTGTGCCGAGCACTTGTG ATGTTGCTCGAAGTTCGAATGGATCGCCTGCTTCCTCACATGCATAATATAGTTGAGTAC ATGCTACAGAGGACTCAAGATCAAGATGAAAATGTGGCTTTAGAAGCCTGTGAATTTTGG CTAACTTTAGCTGAACAGCCAATATGCAAAGATGTACTCGTAAGGCATCTTCCTAAGTTG ATTCCTGTGTTAGTGAATGGCATGAAGTACTCAGACATAGATATTATCCTACTTAAGGGT GATGTTGAAGAAGACGAAACGATTCCTGATAGTGAACAGGATATACGGCCACGTTTTCAC CGATCGAGGACGGTGGCTCAGCAGCATGATGAAGATGGAATTGAAGAGGAAGATGATGAT GATGATGAAATTGATGATGATGATACAATTTCTGACTGGAATCTAAGAAAATGTTCTGCT GCTGCCCTGGATGTTCTTGCAAATGTGTATCGTGATGAACTGCTGCCACATATTTTGCCC CTTTTGAAAGAATTACTTTTTCATCATGAATGGGTTGTTAAAGAATCAGGCATTTTGGTT TTAGGAGCAATTGCTGAAGGTTGCATGCAGGGCATGATTCCATACTTGCCTGAGCTTATT CCTCACCTTATTCAGTGCCTCTCTGATAAAAAGGCTCTTGTGCGTTCCATAACATGCTGG ACTCTTAGCCGCTATGCACACTGGGTGGTCAGCCAGCCGCCAGACACGTACCTGAAGCCA TTAATGACAGAATTGCTAAAGCGCATCCTGGATAGCAACAAGAGAGTACAAGAAGCTGCC TGCAGTGCCTTTGCTACCCTAGAAGAGGAGGCTTGTACAGAACTTGTTCCTTACCTTGCT TATATACTTGATACCCTGGTCTTTGCATTTAGTAAATACCAGCATAAGAACCTGCTCATT CTTTACGATGCCATAGGAACATTAGCAGATTCAGTAGGACATCATTTAAACAAACCAGAA TATATTCAGATGCTAATGCCTCCACTGATCCAGAAATGGAACATGTTAAAGGATGAAGAT AAAGATCTCTTCCCTTTACTTGAGTGCCTATCTTCAGTTGCCACAGCACTGCAGTCTGGA TTCCTTCCGTACTGTGAACCTGTGTATCAGCGTTGTGTAAACCTAGTACAGAAGACTCTT GCACAAGCCATGCTAAACAATGCTCAACCAGATCAATATGAAGCTCCAGATAAAGATTTT ATGATAGTGGCTCTTGATTTACTGAGTGGCCTGGCTGAAGGACTTGGAGGCAACATTGAA CAGCTGGTAGCCCGAAGTAACATCCTGACACTAATGTATCAGTGCATGCAGGATAAAATG CCAGAAGTTCGACAGAGTTCTTTTGCCCTGTTAGGTGACCTCACAAAAGCTTGCTTTCAG CATGTTAAGCCTTGTATAGCTGATTTCATGCCAATATTGGGAACCAACCTAAATCCAGAA TTCATTTCAGTCTGCAACAATGCCACATGGGCAATTGGAGAAATCTCCATTCAAATGGGT ATAGAGATGCAGCCTTATATTCCTATGGTGTTGCACCAGCTTGTAGAAATCATTAACAGA CCCAACACACCAAAGACGTTGTTAGAGAATACAGCAATAACAATTGGTCGTCTTGGTTAC GTTTGTCCTCAAGAGGTGGCCCCCATGCTACAGCAGTTTATAAGACCCTGGTGCACCTCT CTGAGAAACATAAGAGACAATGAGGAAAAGGATTCAGCATTCCGTGGAATTTGTACCATG ATCAGTGTGAATCCCAGTGGCGTAATCCAAGATTTTATATTTTTTTGTGATGCCGTTGCA TCATGGATTAACCCAAAAGATGATCTCAGAGACATGTTCTGTAAGATCCTTCATGGATTT AAAAATCAAGTTGGCGATGAAAATTGGAGGCGTTTCTCTGACCAGTTTCCTCTTCCCTTA AAAGAGCGTCTTGCAGCTTTTTATGGTGTTTAA Clone variation with respect to NM_153188.2 1473 c=>t >OriGene 5' read for NM_153188 unedited
GGGGGGGGGGGGGAANNNNTTTNTTTAAANNNNGTTTTACCCCCGCCCGTTGCCNCATTG GGCGGTAGGCGTGTACGGTGGGNAGTCTATATAAGCAGAGCTCATTTAGGTGACACTATA GAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCGAATTCGGCACGAGGGGCGGCCGGG CTGCCAGGAGCAGTTCCGCCGGGTTTCACTGTCCGTGACTTCCTTCGGGGCACCTCAGGC AGCAAACCAAGATGGAGTATGAGTGGAAACCTGACGAGCAAGGGCTTCAGCAAATCCTGC AGCTGTTGAAGGAGTCCCAGTCCCCAGACACCACCATCCAGAGAACCGTGCAACAAAAAC TGGAACAACTTAATCAGTATCCAGACTTTAACAACTACTTGATTTTTGTTCTTACAAAAT TAAAATCTGAAGATGAACCCACAAGATCATTGAGTGGTCTTATCTTGAAGAATAATGTGA AAGCACACTTTCAGAACTTCCCAAATGGTGTAACAGACTTTATTAAAAGTGAATGTTTAA ATAATATTGGTGACTCCTCTCCTCTGATTAGAGCCACTGTTGGTATTTTGATCACAACTA TAGCCTCCAAGGGAGAATTGCAGAATTGGCCTGACCTCTTACCAAAACTCTGTAGCCTGT TGGATTCTGAAGATTATAATACCTGTGAGGGAGCATTTGGTGCCCTTCAGAAGATTTGTG AAGATTCTGCTGAGATTTTAGACAGTGATGTTTTAGATCGTCCTCTCAACATCATGATTC CCAAATTTTTACAGTTCTTCAAGCATAGTAGTCCAAAATAAGGTCTCACGCTGTTGCATG TGTCAAATCAGTTATCATCAGTAGGACTCAAGCTCTAATGTNGCACATTGATTCTTTTAT TGAGAATCTCTTTGCATTAGCTGGTGATGAAGAACCAGAGGTACGGAAA >OriGene 3' read for NM_153188 unedited
GCACTACTATGTACGTGGCCGCTTCNTANATCGAGTTTTTTTTTTTTTTTTTTGCTTCTT CACATCCACTGGCGGATTGTAACTGGGAGAATATTTCCACCCACAAAGGCTCCAGATGTT AAAACGTTTCCCAACATCGACTTAATACAGTGACGGCAACACCTCCCTCCCGCCCCTCCC AGTAGGGTTGGGATTGTACTGTATTCCCTACTGGTTTACCCTTCCCCCCTGTAAAGGGTA ACATTTTCCCTGGGTGCAGAGGCTCCCTTATAGTCTCCAAGACTGAAGGACCCCTAATTT TGGGACTGCAGCTTAAGTGTATTAGATTAAACACCATAAAAAGCTGCAAGACGCTCTTTT AAGGGAAGAGGAAACTGGTCAGAGAAACGCCTCCAATTTTCATCGCCAACTTGATTTTTA AATCCATGAAGGATCTTACAGAACATGTCTCTGAGATCATCTTTTGGGTTAATCCATGAT GCAACGGCATCACAAAAAAATATAAAATCTTGGATTACGCCACTGGGATTCACACTGATC ATGGTACAAATTCCACGGAATGCTGAATCCTTTTCCTCATTGTCTCTTATGTTTCTCAGA GAGGTGCACCAAGGTCTTATAAACTGCTGTAGCATGGGGGCCACCTCTTGAAGACAAACG TAACCAAGACGACCAAATGGTATTGCTGGATTCTCTAACACGTCTTAGGTGGGTTGGGTC TGTTAATGATTTCTACAAGCTGGGGCACACCCTAAGAATATAAAGGCTGCATTTCTTTTC CCCTTTGAATGGGGATTTCTCCATTGGCCCTGTGGCATTGTTGCAGACGGAAAGGAATCT GGGATTTAGGTTGGGTCCCCAATTTGGCTGGAAACA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_153188 |
| Insert Size | 3200 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_153188.1, NP_694858.1 |
| RefSeq Size | 3026 bp |
| RefSeq ORF | 2673 bp |
| Locus ID | 3842 |
| UniProt ID | Q92973 |
| Domains | Armadillo_seg, IBN_NT |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in several transcript variants encoding different proteins. [provided by RefSeq, Jun 2018] Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. Variants 2, 3, and 4 all encode the same isoform (2). |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The ciliary targeting of membrane proteins by a ternary complex comprising transportin1, Rab8 and the ciliary targeting signal
,Madugula, V;Lu, L;,
Thesis
[TNPO1]
|
|
IPO3 mediated nonclassical nuclear import of NEMO drives DNA damage-dependent NF-?B activation
,Hwang, B;McCool, K;Wan, J;Wuerzberger-Davis, SM;Young, EW;Choi, EY;Cingolani, G;Weaver, BA;Miyamoto, S;,
J. Biol. Chem.
,PubMed ID 26060253
[TNPO1]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC203783 | TNPO1 (Myc-DDK-tagged)-Human transportin 1 (TNPO1), transcript variant 2 |
CNY 9,776.00 |
|
| RC203783L1 | Lenti-ORF clone of TNPO1 (Myc-DDK-tagged)-Human transportin 1 (TNPO1), transcript variant 2 |
CNY 5,890.00 |
|
| RC203783L2 | Lenti-ORF clone of TNPO1 (mGFP-tagged)-Human transportin 1 (TNPO1), transcript variant 2 |
CNY 12,176.00 |
|
| RC203783L3 | Lenti-ORF clone of TNPO1 (Myc-DDK-tagged)-Human transportin 1 (TNPO1), transcript variant 2 |
CNY 5,890.00 |
|
| RC203783L4 | Lenti-ORF clone of TNPO1 (mGFP-tagged)-Human transportin 1 (TNPO1), transcript variant 2 |
CNY 5,890.00 |
|
| RG203783 | TNPO1 (tGFP-tagged) - Human transportin 1 (TNPO1), transcript variant 2 |
CNY 4,370.00 |
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