PTP epsilon (PTPRE) (NM_006504) Human Untagged Clone
CAT#: SC109676
PTPRE (untagged)-Human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1
CNY 5,136.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | HPTPE; PTPE; R-PTP-EPSILON |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF sequence for NM_006504 edited
CGGCCGCGAAATTCGGCACGAGGCCTCGTGCCGAATTCGGCACGAGGGGAATACTCAGTA AATGATGTATTGCCTTTCGCATCAGTAGCCTGCTTGGAAATGTTCAAATTATCAGCCCAG GAGACTCCAGTGCTGTGGACATGGGTCTGAACGAATTGATCACCTAGGGGCTACTGAGAA CGCGGTGCTCTGTCCACCATGGAGCCCTTGTGTCCACTCCTGCTGGTGGGTTTTAGCTTG CCGCTCGCCAGGGCTCTCAGGGGCAACGAGACCACTGCCGACAGCAACGAGACAACCACG ACCTCAGGCCCTCCGGACCCGGGCGCCTCCCAGCCGCTGCTGGCCTGGCTGCTACTGCCG CTGCTGCTCCTCCTCCTCGTGCTCCTTCTCGCCGCCTACTTCTTCAGGTTCAGGAAGCAG AGGAAAGCTGTGGTCAGCACCAGCGACAAGAAGATGCCCAACGGAATCTTGGAGGAGCAA GAGCAGCAAAGGGTGATGCTGCTCAGCAGGTCACCCTCAGGGCCCAAGAAGTATTTTCCC ATCCCCGTGGAGCACCTGGAGGAGGAGATCCGTATCAGATCCGCCGACGACTGCAAGCAG TTTCGGGAGGAGTTCAACTCATTGCCATCTGGACACATACAAGGAACTTTTGAACTGGCA AATAAAGAAGAAAACAGAGAAAAAAACAGATATCCCAACATCCTTCCCAATGACCATTCT AGGGTGATTCTGAGCCAACTGGATGGAATTCCCTGTTCAGACTACATCAATGCTTCCTAC ATAGATGGTTACAAAGAGAAGAATAAATTCATAGCAGCTCAAGGTCCCAAACAGGAAACG GTTAACGACTTCTGGAGAATGGTCTGGGAGCAAAAGTCTGCGACCATCGTCATGTTAACA AACTTGAAAGAAAGGAAAGAGGAAAAGTGCCATCAGTACTGGCCCGACCAAGGCTGCTGG ACCTATGGAAACATCCGGGTGTGCGTGGAGGACTGCGTGGTTTTGGTCGACTACACCATC CGGAAGTTCTGCATACAGCCACAGCTCCCCGACGGCTGCAAAGCCCCCAGGCTGGTCTCA CAGCTGCACTTCACCAGCTGGCCCGACTTCGGAGTGCCTTTTACCCCCATTGGGATGCTG AAGTTCCTCAAGAAAGTAAAGACGCTCAACCCCGTGCACGCTGGGCCCATCGTGGTCCAC TGTAGCGCGGGCGTGGGCCGGACGGGCACCTTCATTGTGATCGATGCCATGATGGCCATG ATGCACGCGGAGCAGAAGGTGGATGTGTTTGAATTTGTGTCTCGAATCCGTAATCAGCGC CCTCAGATGGTTCAAACGGATATGCAGTACACGTTCATCTACCAAGCCTTACTCGAGTAC TACCTCTACGGGGACACAGAGCTGGACGTGTCCTCCCTGGAGAAGCACCTGCAGACCATG CACGGCACCACCACCCACTTCGACAAGATCGGGCTGGAGGAGGAGTTCAGGAAATTGACA AATGTCCGGATCATGAAGGAGAACATGAGGACGGGCAACTTGCCGGCAAACATGAAGAAG GCCAGGGTCATCCAGATCATCCCGTATGACTTCAACCGAGTGATCCTTTCCATGAAAAGG GGTCAAGAATACACAGACTACATCAACGCATCCTTCATAGACGGCTACCGACAGAAGGAC TATTTCATCGCCACCCAGGGGCCACTGGCACACACGGTTGAGGACTTCTGGAGGATGATC TGGGAATGGAAGTCCCACACTATCGTGATGCTGACGGAGGTGCAGGAGAGAGAGCAGGAT AAATGCTACCAGTATTGGCCAACCGAGGGCTCAGTTACTCATGGAGAAATAACGATTGAG ATAAAGAATGATACCCTTTCAGAAGCCATCAGTATACGAGACTTTCTGGTCACTCTCAAT CAGCCCCAGGCCCGCCAGGAGGAGCAGGTCCGAGTAGTGCGCCAGTTTCACTTCCACGGC TGGCCTGAGATCGGGATTCCCGCCGAGGGCAAAGGCATGATTGACCTCATCGCAGCCGTG CAGAAGCAGCAGCAGCAGACAGGCAACCACCCCATCACCGTGCACTGCAGTGCCGGAGCT GGGCGAACAGGTACATTCATAGCCCTCAGCAACATTTTGGAGCGAGTAAAAGCCGAGGGA CTTTTAGATGTATTTCAAGCTGTGAAGAGTTTACGACTTCAGAGACCACATATGGTGCAA ACCCTGGAACAGTATGAATTCTGCTACAAAGTGGTACAAGATTTTATTGATATATTTTCT GATTATGCTAATTTCAAATGAAGATTCCTGCCTTAAAATATTTTTTTAATTTAATGGTCA GTATATTTTGTAAAAATCATGTTAATTTATTTCATAGTTGACATTAATATCTTCCCTAAT TTCTTTGTATATATTTTGTTATGCCTTAAAGGCCACCTGCTATACAGTTGTTAAATCTTA AATATGCTTTTTAAAAATTGGATAATGTATTAAGGTCAAATAATATCCCATAAAATATAT ATTTCTGCTAATATTA >OriGene 5' read for NM_006504 unedited
CTTGGGCCGGGCCTCGTGCCTTTTGGGGACGAGGGGNAATACTCAGTAAATGATGTATTG CCTTTCGCATCAGTAGCCTGCTTGGAAATGTTCAAATTATCAGCCCAGGAGACTCCAGTG CTGTGGACATGGGTCTGAACGAATTGATCACCTAGGGAGCTACTAGAAAACTCGGCTGCG CTGTCCACCATGGAGCCCTTGTGTCCACTCCTGCTGGTGGGTTTTAGCTTGCCGCTCGCC AGGGCTCTCAGGGGCAACGAGACCACTGCCGACAGCAACGAGACAACCACGACCTCAGGC CCTCCGGACCCGGGCGCCTCCCAGCCGCTGCTGGCCTGGCTGCTACTGCCGCTGCTGCTC CTCCTCCTCGTGCTCCTTCTCGCCGCCTACTTCTTCAGGTTCAGGAAGCAGAGGAAAGCT GTGGTCAGCACCAGCGACAAGAAGATGCCCAACGGAATCTTGGAGGAGCAAGAGCAGCAA AGGGTGATGCTGCTCAGCAGGTCACCCTCAGGGCCCAAGAAGTATTTTCCCATCCCCGTG GAGCACCTGGAGGAGGAGATCCGTATCAGATCCGCCGACGACTGCAAGCAGTTTCGGGAG GAGTTCAACTCATTGCCCTCTGGACACATACAAGGAACTTTTGAACCTGGCAATTACGAA GAAAACAGAGGAAAAAACAGATATCCCAACATCCTTTCAAAAGACCATTCTAGGGTGATC CTGAGCCAACTGGATGGAATTCCCTGTTCAGACTACATCAATGCTTCCCACTAGATGGTT ACAAAGAGGAAAATAAATTCCTAGCAGCCTAAGGTCCCAAACAGAAAACGGTAACGACTC CTGAAAATGGTCCCGGGAGCAAAATCTGCGACCTTCGTT >OriGene 3' read for NM_006504 unedited
NTTTCACTCTGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTC CCCGTCAGTCAATCTTATCTGGTAATGGGATCATTACTGTTATCCAGTGTCAATGGTCTC AGTAGTATTTCCATTCAAAAATAATTTAGCTTTTAAATTAAGGATTTCTCTTTTTGTTTT ATTAAACATTGAAAGGTGGGACTTTAAAAAATGGTATAAATCTAGATTTTAAGGATTCTT TTCTTACAAACTGTCTCAGCTTTTTACAAGAAATGTTTAAATACCAAAATGCTGCTCAGA AAATTTAAAGTTTAATTGCCCGTGGTTATTCTACTGTTTCTATCCTAATGTGTGCTCCTC TGTACTGCGTGTGTAAGACGCTCAGTTCATCTGAATGTTTGGATGGGAAGTTTTGTGTTG AGCCTCCAGGCATAGCACTGGACCAGCCCAGGCCGCTGTGGCAAAACGGGAGGGGAGAAT GGGAGAGGCAGCTGGTTTTTTTCTGAGGGTGGTCTGGGCCAAACGACAGGCAGCTGGACA GCAAATGGTGCTTTGGGGTGTAACTCCGATGGCTGGTTTTGTTGTACCCAACGCCGTGGG TCAACGGGACCACCCAGCATTTACATCTCTTCTCGTTCAGCCAAGATAGTGTAAACACAG TCTTGATGGTGTAGACACAGCATTTTAAAATATTATTTATAGTCACCAGCTACTCTAGTG TGTTTTAGACCTGGATTCAGGTTGTAAAGACTTCTTTGATCTTTAAATGTAAAGATAAAC CACATGGACCCGAAACTGAGAACTNTACACGAGTCCCCATTTACATTGTACCATCACGAA CAGTTTGCCTTCCAAAATGCTGCTGGTCAGGGTTGTGATCCACTGCTAGGAAAGGCCATT TCGCACTGACTTTTGAGTTTTAACCGTTTTCT |
Restriction Sites | NotI-NotI |
ACCN | NM_006504 |
Insert Size | 3460 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_006504.3, NP_006495.1 |
RefSeq Size | 5376 bp |
RefSeq ORF | 2103 bp |
Locus ID | 5791 |
UniProt ID | P23469 |
Domains | Y_phosphatase, PTPc_motif |
Protein Families | Druggable Genome, Phosphatase, Transmembrane |
Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels. [provided by RefSeq, Oct 2015] Transcript Variant: This variant (1) lacks a 5' exon compared to variant 3. The resulting isoform (1) is shorter at the N-terminus compared to isoform 3. The encoded protein is a receptor type isoform of this PTP. Variants 1, 4, and 5 all encode the same isoform (1). |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC207950 | PTPRE (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1 |
CNY 5,128.00 |
|
RC207950L1 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1, Myc-DDK-tagged |
CNY 7,528.00 |
|
RC207950L2 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RC207950L3 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
RC207950L4 | Lenti ORF clone of Human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
RG207950 | PTPRE (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, E (PTPRE), transcript variant 1 |
CNY 6,728.00 |
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