Tankyrase 2 (TNKS2) (NM_025235) Human Untagged Clone

CAT#: SC110047

TNKS2 (untagged)-Human tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 (TNKS2)



  "NM_025235" in other vectors (6)

CNY 12,184.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
Goat Anti-Tankyrase 2 Antibody
    • 100 ug

CNY 5,371.00


TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Synonyms ARTD6; PARP-5b; PARP-5c; PARP5B; PARP5C; pART6; TANK2; TNKL
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_025235 edited
AGCGCGTCTTCTCCGGGGGGCCTCGCCCTCCTGCTCGCGGGGCCGGGGCTCCTGCTCCGG
TTGCTGGCGCTGTTGCTGGCTGTGGCGGCGGCCAGGATCATGTCGGGTCGCCGCTGCGCC
GGCGGGGGAGCGGCCTGCGCGAGCGCCGCGGCCGAGGCCGTGGAGCCGGCCGCCCGAGAG
CTGTTCGAGGCGTGCCGCAACGGGGACGTGGAACGAGTCAAGAGGCTGGTGACGCCTGAG
AAGGTGAACAGCCGCGACACGGCGGGCAGGAAATCCACCCCGCTGCACTTCGCCGCAGGT
TTTGGGCGGAAAGACGTAGTTGAATATTTGCTTCAGAATGGTGCAAATGTCCAAGCACGT
GATGATGGGGGCCTTATTCCTCTTCATAATGCATGCTCTTTTGGTCATGCTGAAGTAGTC
AATCTCCTTTTGCGACATGGTGCAGACCCCAATGCTCGAGATAATTGGAATTATACTCCT
CTCCATGAAGCTGCAATTAAAGGAAAGATTGATGTTTGCATTGTGCTGTTACAGCATGGA
GCTGAGCCAACCATCCGAAATACAGATGGAAGGACAGCATTGGATTTAGCAGATCCATCT
GCCAAAGCAGTGCTTACTGGTGAATATAAGAAAGATGAACTCTTAGAAAGTGCCAGGAGT
GGCAATGAAGAAAAAATGATGGCTCTACTCACACCATTAAATGTCAACTGCCACGCAAGT
GATGGCAGAAAGTCAACTCCATTACATTTGGCAGCAGGATATAACAGAGTAAAGATTGTA
CAGCTGTTACTGCAACATGGAGCTGATGTCCATGCTAAAGATAAAGGTGATCTGGTACCA
TTACACAATGCCTGTTCTTATGGTCATTATGAAGTAACTGAACTTTTGGTCAAGCATGGT
GCCTGTGTAAATGCAATGGACTTGTGGCAATTCACTCCTCTTCATGAGGCAGCTTCTAAG
AACAGGGTTGAAGTATGTTCTCTTCTCTTAAGTTATGGTGCAGACCCAACACTGCTCAAT
TGTCACAATAAAAGTGCTATAGACTTGGCTCCCACACCACAGTTAAAAGAAAGATTAGCA
TATGAATTTAAAGGCCACTCGTTGCTGCAAGCTGCACGAGAAGCTGATGTTACTCGAATC
AAAAAACATCTCTCTCTGGAAATGGTGAATTTCAAGCATCCTCAAACACATGAAACAGCA
TTGCATTGTGCTGCTGCATCTCCATATCCCAAAAGAAAGCAAATATGTGAACTGTTGCTA
AGAAAAGGAGCAAACATCAATGAAAAGACTAAAGAATTCTTGACTCCTCTGCACGTGGCA
TCTGAGAAAGCTCATAATGATGTTGTTGAAGTAGTGGTGAAACATGAAGCAAAGGTTAAT
GCTCTGGATAATCTTGGTCAGACTTCTCTACACAGAGCTGCATATTGTGGTCATCTACAA
ACCTGCCGCCTACTCCTGAGCTATGGGTGTGATCCTAACATTATATCCCTTCAGGGCTTT
ACTGCTTTACAGATGGGAAATGAAAATGTACAGCAACTCCTCCAAGAGGGTATCTCATTA
GGTAATTCAGAGGCAGACAGACAATTGCTGGAAGCTGCAAAGGCTGGAGATGTCGAAACT
GTAAAAAAACTGTGTACTGTTCAGAGTGTCAACTGCAGAGACATTGAAGGGCGTCAGTCT
ACACCACTTCATTTTGCAGCTGGGTATAACAGAGTGTCCGTGGTGGAATATCTGCTACAG
CATGGAGCTGATGTGCATGCTAAAGATAAAGGAGGCCTTGTACCTTTGCACAATGCATGT
TCTTATGGACATTATGAAGTTGCAGAACTTCTTGTTAAACATGGAGCAGTAGTTAATGTA
GCTGATTTATGGAAATTTACACCTTTACATGAAGCAGCAGCAAAAGGAAAATATGAAATT
TGCAAACTTCTGCTCCAGCATGGTGCAGACCCTACAAAAAAAAACAGGGATGGAAATACT
CCTTTGGATCTTGTTAAAGATGGAGATACAGATATTCAAGATCTGCTTAGGGGAGATGCA
GCTTTGCTAGATGCTGCCAAGAAGGGTTGTTTAGCCAGAGTGAAGAAGTTGTCTTCTCCT
GATAATGTAAATTGCCGCGATACCCAAGGCAGACATTCAACACCTTTACATTTAGCAGCT
GGTTATAATAATTTAGAAGTTGCAGAGTATTTGTTACAACACGGAGCTGATGTGAATGCC
CAAGACAAAGGAGGACTTATTCCTTTACATAATGCAGCATCTTACGGGCATGTAGATGTA
GCAGCTCTACTAATAAAGTATAATGCATGTGTCAATGCCACGGACAAATGGGCTTTCACA
CCTTTGCACGAAGCAGCCCAAAAGGGACGAACACAGCTTTGTGCTTTGTTGCTAGCCCAT
GGAGCTGACCCGACTCTTAAAAATCAGGAAGGACAAACACCTTTAGATTTAGTTTCAGCA
GATGATGTCAGCGCTCTTCTGACAGCAGCCATGCCCCCATCTGCTCTGCCCTCTTGTTAC
AAGCCTCAAGTGCTCAATGGTGTGAGAAGCCCAGGAGCCACTGCAGATGCTCTCTCTTCA
GGTCCATCTAGCCCATCAAGCCTTTCTGCAGCCAGCAGTCTTGACAACTTATCTGGGAGT
TTTTCAGAACTGTCTTCAGTAGTTAGTTCAAGTGGAACAGAGGGTGCTTCCAGTTTGGAG
AAAAAGGAGGTTCCAGGAGTAGATTTTAGCATAACTCAATTCGTAAGGAATCTTGGACTT
GAGCACCTAATGGATATATTTGAGAGAGAACAGATCACTTTGGATGTATTAGTTGAGATG
GGGCACAAGGAGCTGAAGGAGATTGGAATCAATGCTTATGGACATAGGCACAAACTAATT
AAAGGAGTCGAGAGACTTATCTCCGGACAACAAGGTCTTAACCCATATTTAACTTTGAAC
ACCTCTGGTAGTGGAACAATTCTTATAGATCTGTCTCCTGATGATAAAGAGTTTCAGTCT
GTGGAGGAAGAGATGCAAAGTACAGTTCGAGAGCACAGAGATGGAGGTCATGCAGGTGGA
ATCTTCAACAGATACAATATTCTCAAGATTCAGAAGGTTTGTAACAAGAAACTATGGGAA
AGATACACTCACCGGAGAAAAGAAGTTTCTGAAGAAAACCACAACCATGCCAATGAACGA
ATGCTATTTCATGGGTCTCCTTTTGTGAATGCAATTATCCACAAAGGCTTTGATGAAAGG
CATGCGTACATAGGTGGTATGTTTGGAGCTGGCATTTATTTTGCTGAAAACTCTTCCAAA
AGCAATCAATATGTATATGGAATTGGAGGAGGTACTGGGTGTCCAGTTCACAAAGACAGA
TCTTGTTACATTTGCCACAGGCAGCTGCTCTTTTGCCGGGTAACCTTGGGAAAGTCTTTC
CTGCAGTTCAGTGCAATGAAAATGGCACATTCTCCTCCAGGTCATCACTCAGTCACTGGT
AGGCCCAGTGTAAATGGCCTAGCATTAGCTGAATATGTTATTTACAGAGGAGAACAGGCT
TATCCTGAGTATTTAATTACTTACCAGATTATGAGGCCTGAAGGTATGGTCGATGGATAA
ATAGTTATTTTAAGAAACTAATTCCACTGAACCTAAAATCATCAAAGCAGCAGTGGCCTC
TACGTTTTACTCCTTTGCTGAAAAAAAATCATCTTGCCCAAGCGCGTCTTCTCCGGGGGG
CCTCGCCCTCCTGCTCGCGGGGCCGGGGCTCCTGCTCCGGTTGCTGGCGCTGTTGCTGGC
TGTGGCGGCGGCCAGGATCATGTCGGGTCGCCGCTGCGCCGGCGGGGGAGCGGCCTGCGC
GAGCGCCGCGGCCGAGGCCGTGGAGCCGGCCGCCCGAGAGCTGTTCGAGGCGTGCCGCAA
CGGGGACGTGGAACGAGTCAAGAGGCTGGTGACGCCTGAGAAGGTGAACAGCCGCGACAC
GGCGGGCAGGAAATCCACCCCGCTGCACTTCGCCGCAGGTTTTGGGCGGAAAGACGTAGT
TGAATATTTGCTTCAGAATGGTGCAAATGTCCAAGCACGTGATGATGGGGGCCTTATTCC
TCTTCATAATGCATGCTCTTTTGGTCATGCTGAAGTAGTCAATCTCCTTTTGCGACATGG
TGCAGACCCCAATGCTCGAGATAATTGGAATTATACTCCTCTCCATGAAGCTGCAATTAA
AGGAAAGATTGATGTTTGCATTGTGCTGTTACAGCATGGAGCTGAGCCAACCATCCGAAA
TACAGATGGAAGGACAGCATTGGATTTAGCAGATCCATCTGCCAAAGCAGTGCTTACTGG
TGAATATAAGAAAGATGAACTCTTAGAAAGTGCCAGGAGTGGCAATGAAGAAAAAATGAT
GGCTCTACTCACACCATTAAATGTCAACTGCCACGCAAGTGATGGCAGAAAGTCAACTCC
ATTACATTTGGCAGCAGGATATAACAGAGTAAAGATTGTACAGCTGTTACTGCAACATGG
AGCTGATGTCCATGCTAAAGATAAAGGTGATCTGGTACCATTACACAATGCCTGTTCTTA
TGGTCATTATGAAGTAACTGAACTTTTGGTCAAGCATGGTGCCTGTGTAAATGCAATGGA
CTTGTGGCAATTCACTCCTCTTCATGAGGCAGCTTCTAAGAACAGGGTTGAAGTATGTTC
TCTTCTCTTAAGTTATGGTGCAGACCCAACACTGCTCAATTGTCACAATAAAAGTGCTAT
AGACTTGGCTCCCACACCACAGTTAAAAGAAAGATTAGCATATGAATTTAAAGGCCACTC
GTTGCTGCAAGCTGCACGAGAAGCTGATGTTACTCGAATCAAAAAACATCTCTCTCTGGA
AATGGTGAATTTCAAGCATCCTCAAACACATGAAACAGCATTGCATTGTGCTGCTGCATC
TCCATATCCCAAAAGAAAGCAAATATGTGAACTGTTGCTAAGAAAAGGAGCAAACATCAA
TGAAAAGACTAAAGAATTCTTGACTCCTCTGCACGTGGCATCTGAGAAAGCTCATAATGA
TGTTGTTGAAGTAGTGGTGAAACATGAAGCAAAGGTTAATGCTCTGGATAATCTTGGTCA
GACTTCTCTACACAGAGCTGCATATTGTGGTCATCTACAAACCTGCCGCCTACTCCTGAG
CTATGGGTGTGATCCTAACATTATATCCCTTCAGGGCTTTACTGCTTTACAGATGGGAAA
TGAAAATGTACAGCAACTCCTCCAAGAGGGTATCTCATTAGGTAATTCAGAGGCAGACAG
ACAATTGCTGGAAGCTGCAAAGGCTGGAGATGTCGAAACTGTAAAAAAACTGTGTACTGT
TCAGAGTGTCAACTGCAGAGACATTGAAGGGCGTCAGTCTACACCACTTCATTTTGCAGC
TGGGTATAACAGAGTGTCCGTGGTGGAATATCTGCTACAGCATGGAGCTGATGTGCATGC
TAAAGATAAAGGAGGCCTTGTACCTTTGCACAATGCATGTTCTTATGGACATTATGAAGT
TGCAGAACTTCTTGTTAAACATGGAGCAGTAGTTAATGTAGCTGATTTATGGAAATTTAC
ACCTTTACATGAAGCAGCAGCAAAAGGAAAATATGAAATTTGCAAACTTCTGCTCCAGCA
TGGTGCAGACCCTACAAAAAAAAACAGGGATGGAAATACTCCTTTGGATCTTGTTAAAGA
TGGAGATACAGATATTCAAGATCTGCTTAGGGGAGATGCAGCTTTGCTAGATGCTGCCAA
GAAGGGTTGTTTAGCCAGAGTGAAGAAGTTGTCTTCTCCTGATAATGTAAATTGCCGCGA
TACCCAAGGCAGACATTCAACACCTTTACATTTAGCAGCTGGTTATAATAATTTAGAAGT
TGCAGAGTATTTGTTACAACACGGAGCTGATGTGAATGCCCAAGACAAAGGAGGACTTAT
TCCTTTACATAATGCAGCATCTTACGGGCATGTAGATGTAGCAGCTCTACTAATAAAGTA
TAATGCATGTGTCAATGCCACGGACAAATGGGCTTTCACACCTTTGCACGAAGCAGCCCA
AAAGGGACGAACACAGCTTTGTGCTTTGTTGCTAGCCCATGGAGCTGACCCGACTCTTAA
AAATCAGGAAGGACAAACACCTTTAGATTTAGTTTCAGCAGATGATGTCAGCGCTCTTCT
GACAGCAGCCATGCCCCCATCTGCTCTGCCCTCTTGTTACAAGCCTCAAGTGCTCAATGG
TGTGAGAAGCCCAGGAGCCACTGCAGATGCTCTCTCTTCAGGTCCATCTAGCCCATCAAG
CCTTTCTGCAGCCAGCAGTCTTGACAACTTATCTGGGAGTTTTTCAGAACTGTCTTCAGT
AGTTAGTTCAAGTGGAACAGAGGGTGCTTCCAGTTTGGAGAAAAAGGAGGTTCCAGGAGT
AGATTTTAGCATAACTCAATTCGTAAGGAATCTTGGACTTGAGCACCTAATGGATATATT
TGAGAGAGAACAGATCACTTTGGATGTATTAGTTGAGATGGGGCACAAGGAGCTGAAGGA
GATTGGAATCAATGCTTATGGACATAGGCACAAACTAATTAAAGGAGTCGAGAGACTTAT
CTCCGGACAACAAGGTCTTAACCCATATTTAACTTTGAACACCTCTGGTAGTGGAACAAT
TCTTATAGATCTGTCTCCTGATGATAAAGAGTTTCAGTCTGTGGAGGAAGAGATGCAAAG
TACAGTTCGAGAGCACAGAGATGGAGGTCATGCAGGTGGAATCTTCAACAGATACAATAT
TCTCAAGATTCAGAAGGTTTGTAACAAGAAACTATGGGAAAGATACACTCACCGGAGAAA
AGAAGTTTCTGAAGAAAACCACAACCATGCCAATGAACGAATGCTATTTCATGGGTCTCC
TTTTGTGAATGCAATTATCCACAAAGGCTTTGATGAAAGGCATGCGTACATAGGTGGTAT
GTTTGGAGCTGGCATTTATTTTGCTGAAAACTCTTCCAAAAGCAATCAATATGTATATGG
AATTGGAGGAGGTACTGGGTGTCCAGTTCACAAAGACAGATCTTGTTACATTTGCCACAG
GCAGCTGCTCTTTTGCCGGGTAACCTTGGGAAAGTCTTTCCTGCAGTTCAGTGCAATGAA
AATGGCACATTCTCCTCCAGGTCATCACTCAGTCACTGGTAGGCCCAGTGTAAATGGCCT
AGCATTAGCTGAATATGTTATTTACAGAGGAGAACAGGCTTATCCTGAGTATTTAATTAC
TTACCAGATTATGAGGCCTGAAGGTATGGTCGATGGATAAATAGTTATTTTAAGAAACTA
ATTCCACTGAACCTAAAATCATCAAAGCAGCAGTGGCCTCTACGTTTTACTCCTTTGCTG
AAAAAAAATCATCTTGCCCA
>OriGene 5' read for NM_025235 unedited
TGGATTTGTATCCGACTTACTATAGGGNNCGGCCGCGCAATTCGGCACCAGAACAGCAGG
GAGCCAAGCGGCCCGGGCCCTGAGCGCGTCTTCTCCGGGGGGCCTCGCCCTCCTGCTCGC
GGGGCCGGGGCTCCTGCTCCGGTTGCTGGCGCTGTTGCTGGCTGTGGCGGCGGCCAGGAT
CATGTCGGGTCGCCGCTGCGCCGGCGGGGGAGCGGCCTGCGCGAGCGCCGCGGCCGAGGC
CGTGGAGCCGGCCGCCCGAGAGCTGTTCGAGGCGTGCCGCAACGGGGACGTGGAACGAGT
CAAGAGGCTGGTGACGCCTGAGAAGGTGAACAGCCGCGACACGGCGGCCAGGAAATCCAC
CCCGCTGCACTTCGCCGCAGGTTTTGGGCGGAAAGACGTAGTTGAATATTTGCTTCAGAA
TGGTGCAAATGTCCAAGCACGTGATGATGGGGGCCTTATTCCTCTTCATAATGCATGCTC
TTTTGGTCATGCTGAAGTAGTCAATCTCCTTTTGCGACATGGTGCAGACCCCAATGCTCG
AGATAATTGGAATTATACTCCTCTCCATGAAGCTGCAATTAAAGGAAAGATTGATGTTTG
CATTGTGCTGTTACAGCATGGAGCTGAGCCAACCATCCGAAATACAGATGGAAGGACAGC
ATTGGATTTAGCAGATCCATCTGCCAAAGCAGTGCTTACTGGTGAATATAAGAAAGATGA
ACTCTTNAGAAGTGCCAGGAGTGGCCATGAAGAAAAAATGATGGCTCTACTCCACCATCT
AATGTCAACTGCCACGCCAGTGATGGCAGAAAGTCAACTCCATTACATTTGGCAGCAGGA
TATACAGAGTAAAGATGTACAGCTGNTACTGCACATGGAGCTGATGTCATGCTAAGATTA
AGGTGATCTGGTACATTACACATGCCTGTCTATGTCATTATGAGTACTGACTTTGTCAGC
ATGTGCTGTGTATGCAGN
>OriGene 3' read for NM_025235 unedited
ACCGTGGCCGCANTTTATAGTCGAGTTTTTTTTTTTTTTTTTTTTAACAAGTGAACAGTT
TTATTAAGAATTAAATGAGGGTATGGAATGTGATACAGTACAAGTAAGACACTGAAGATG
GGTATAATAGTACTACTTGCACAAAAAGTTAAATTTCACTTCAAAAAAAAAAATCACAAG
ACAAAAGAAAAAGCAATTCCATCATTATAAAGTAAGCTATTTCATGCAACGTACTAATAC
TCCCCCTCCCCCCAAAACCCCAACTTCCCAACAAACAAAAAGCTATCTGAAAATGCTGCC
ATGCTAACATATGAACCACGGCATATCCATTCATGGAAAAACACACTCATTAAGCAATGG
ATTACATAAAATAACACAGTGTGTGCCGTTGCCAACTCCTAGACCACAATGATTCCGCAT
GAAAAGCACTCCCACATCCACTGATAGGGTGAGATATATGGCCTACCATACCCCACAGAC
CTGTCCACCCACGCCCCTGGATCGTCCCGTTAGCTTGTACGCGCGTACGTGCCCCTTTAC
AATGTTTGTCAATCCCTCTTCTCTCTGTCCGCACTCTCCCGGCGCTTTTTCAACTCGCCC
TTGTCACCCCCTTTTTCCCCACACTTTCTCCCTTCCTCCCCCCCCCTGCTCTTTTCTTAT
TATTTAAGCAACCCCCCCTGTTGTCCCCTTCGCTCATTAGCCGCTTTCCCCCCCCTTTTT
CTTTTATTCTCCTTCCTCCCCCCTTCTTTTTCCCCTCCCTTTCCTTCCCCCCTTCNTACC
CCTCCTCTTCTTTTTTTTTTCCGCACCCCGCACCGTCTTTTATTCTCGCACTGTCCCACG
CCCCCCGTGTTTTTCTCACTCCCCACACCCTTATCCCTTTCCCCCCTCGCGCTCACCATG
CTGTTTTTACGATATCACCATCCTCCACCACGCGCCGTCGCCGCCTCCTATATTTCTCTC
TCGCGCCCCTTACCACAGCACCCACCTTGATTCCCCGCTATCTATCCCAATGTAT
Restriction Sites NotI-NotI     
ACCN NM_025235
Insert Size 5700 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_025235.2, NP_079511.1
RefSeq Size 6189 bp
RefSeq ORF 3501 bp
Locus ID 80351
UniProt ID Q9H2K2
Domains SAM, ANK
Gene Summary Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking (PubMed:11739745, PubMed:11802774, PubMed:19759537, PubMed:21478859, PubMed:23622245, PubMed:25043379). Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation (PubMed:19759537, PubMed:21478859). Also mediates poly-ADP-ribosylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination (PubMed:21478859). Mediates poly-ADP-ribosylation of TERF1, thereby contributing to the regulation of telomere length (PubMed:11739745). Stimulates 26S proteasome activity (PubMed:23622245).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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