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ATP dependent metalloprotease YME1L1 (YME1L1) (NM_014263) Human Untagged Clone
CAT＃: SC110195
YME1L1 (untagged)-Human YME1-like 1 (S. cerevisiae) (YME1L1), nuclear gene encoding mitochondrial protein, transcript variant 3
CNY 5,256.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | FTSH; MEG4; OPA11; PAMP; YME1L |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC110195 sequence for NM_014263 edited (data generated by NextGen Sequencing)
ATGTTTTCCTTGTCGAGCACGGTGCAACCCCAGGTTACAGTTCCTCTGAGTCATCTCATC AATGCCTTCCATACACCAAAAAACACTTCTGTTTCTCTCAGTGGAGTGTCAGTTTCTCAA AACCAGCATCGAGATGTAGTTCCTGAGCATGAGGCTCCCAGCAGTGAGCCTTCACTTAAC TTAAGGGACCTTGGATTATCTGAACTAAAAATTGGACAGATTGATCAGCTGGTAGAAAAT CTACTTCCTGGATTTTGTAAAGGCAAAAACATTTCTTCCCATTGGCATACATCCCATGTC TCTGCACAATCCTTCTTTGAAAATAAATATGGTAACTTAGATATATTTAGTACATTACGT TCCTCTTGCTTGTATCGACATCATTCAAGAGCTCTTCAAAGCATTTGTTCAGATCTTCAG TACTGGCCAGTTTTCATACAGTCTCGGGGTTTTAAAACTTTGAAATCAAGGACACGACGT CTCCAGTCTACCTCCGAGAGATTAGCTGAAACACAGAATATAGCGCCATCATTCGTGAAG GGGTTTCTTTTGCGGGACAGAGGATCAGATGTTGAGAGTTTGGACAAACTCATGAAAACC AAAAATATACYTGAAGCTCACCAAGATGCATTTAAAACTGGTTTTGCGGAAGGTTTTCTG AAAGCTCAAGCACTCACACAAAAAACCAATGATTCCCTAAGGCGAACCCGTCTGATTCTC TTCGTTCTGCTGCTATTCGGCATTTATGGACTTCTAAAAAACCCATTTTTATCTGTCCGC TTCCGGACAACAACAGGGCTTGATTCTGCAGTAGATCCTGTCCAGATGAAAAATGTCACC TTTGAACATGTTAAAGGGGTGGAGGAAGCTAAACAAGAATTACAGGAAGTTGTTGAATTC TTGAAAAATCCACAAAAATTTACTATTCTTGGAGGTAAACTTCCAAAAGGAATTCTTTTA GTTGGACCCCCAGGGACTGGAAAGACACTTCTTGCCCGAGCTGTGGCGGGAGAAGCTGAT GTTCCTTTTTATTATGCTTCTGGATCCGAATTTGATGAGATGTTTGTGGGTGTGGGAGCC AGCCGTATCAGAAATCTTTTTAGGGAAGCAAAGGCGAATGCTCCTTGTGTTATATTTATT GATGAATTAGATTCTGTTGGTGGGAAGAGAATTGAATCTCCAATGCATCCATATTCAAGG CAGACCATAAATCAACTTCTTGCTGAAATGGATGGTTTTAAACCCAATGAAGGAGTTATC ATAATAGGAGCCACAAACTTCCCAGAGGCATTAGATAATGCCTTAATACGTCCTGGTCGT TTTGACATGCAAGTTACAGTTCCAAGGCCAGATGTAAAAGGTCGAACAGAAATTTTGAAA TGGTATCTCAATAAAATAAAGTTTGATCAATCCGTTGATCCAGAAATTATAGYTCGAGGT ACTGTTGGCTTTTCCGGAGCAGAGTTGGAGAATCTTGTGAACCAGGCTGCATTAAAAGCA GCTGTTGATGGAAAAGAAATGGTTACCATGAAGGAGCTGGAGTTTTCCAAAGACAAAATT CTAATGGGGCCTGAAAGAAGAAGTGTGGAAATTGATAACAAAAACAAAACCATCACAGCA TATCATGAATCTGGTCATGCCATTATTGCATATTACACAAAAGATGCAATGCCTATCAAC AAAGCTACAATCATGCCACGGGGGCCAACACTTGGACATGTGTCCCTGTTACCTGAGAAT GACAGATGGAATGAAACTAGAGCCCAGCTGCTTGCACAAATGGATGTTAGTATGGGAGGA AGAGTGGCAGAGGAGCTTATATTTGGAACCGACCATATTACAACAGGTGCTTCCAGTGAT TTTGATAATGCCACTAAAATAGCAAAGCGGATGGTTACCAAATTTGGAATGAGTGAAAAG CTTGGAGTTATGACCTACAGTGATACAGGGAAACTAAGTCCAGAAACCCAATCTGCCATC GAACAAGAAATAAGAATCCTTCTAAGGGACTCATATGAACGAGCAAAACATATCTTGAAA ACTCATGCAAAGGAGCATAAGAATCTCGCAGAAGCTTTATTGACCTATGAGACTTTGGAT GCCAAAGAGATTCAAATTGTTCTTGAGGGGAAAAAGTTGGAAGTGAGATGA Clone variation with respect to NM_014263.2 611 c=>y;1433 c=>y >OriGene 5' read for NM_014263 unedited
CAGCATTTTGTAATCACGACTCACTATAGGGCGGCCGCGCATTCGGCACGAGGGGCAACG GGTCGGAGAAAAAGGAAAAAAGAGGGCTCAGCGCCTCCCCGCCGGGCCGTGGACAGAGGG GCACAGTTTCGGCAGGCGGGTGAGGTCGCTGAGGGCCCGCCGGAGATGTTTTCCTTGTCG AGCACGGTGCAACCCCAGGTTACAGTTCCTCTGAGTCATCTCATCAATGCCTTCCATACA CCAAAAAACACTTCTGTTTCTCTCAGTGGAGTGTCAGTTTCTCAAAACCAGCATCGAGAT GTAGTTCCTGAGCATGAGGCTCCCAGCAGTGAGCCTTCACTTAACTTAAGGGACCTTGGA TTATCTGAACTAAAAATTGGACAGATTGATCAGCTGGTAGAAAATCTACTTCCTGGATTT TGTAAAGGCAAAAACATTTCTTCCCATTGGCATACATCCCATGTCTCTGCACAATCCTTC TTTGAAAATAAATATGGTAACTTAGATATATTTAGTACATTACGTTCCTCTTGCTTGTAT CGACATCATTCAAGAGCTCTTCAAAGCATTTGTTCAGATCTTCAGTACTGGCCAGTTCTC ATACAGTCTCGGGNGTTTAAAACTTTGAAATCAAGGACACGACGTCTCCATTCTACCTCC GAGAGATTACCTGAAACACAGAATATAGCGCCATCTTTCGTGAAGGGGTTTCTTTTGCGG GACAAAGGATCAGATGTTGAGAGTTCGGACACACTCATGAAAACCACCATATACTTGAAG CTCACCAAGAGCATTTAANACTGGTTTGCGGAAAGGTTTCTGAAAGCCCACCCCTTACCC AAANACCATTGATTCCTTAAGGCAACCCGTGTGAATCTCTCCGTTTGCTGTTATCCGGAT TTTTGGACTCTCAANAACCCATTCTTCCTTGCCGCTTC >OriGene 3' read for NM_014263 unedited
CGGGCCGCAATCTAGAATCGAGTTTTTTTTTTTTTTTTTTGGGGACTGAGATTTTTGTTT AATTTTGCTTTTGAAACCAAGCACAGTTATAGTCAAAATGAGGGACATTATTCAGAATGA GGTTATGTATTTATTTAACAAAATACTGCTTCTCTGAAGTACATTTCATTAGGGAGAGTG ACAGTAATGCTAAAAAAAAGAACATGAAAATGCACACAGCATTTCTGAAAGGGTATAATA ATTTATTTAATTTTTTTTTGAGACAGAGTCTCACTCTGTCACCCAAGCTGGAGTGCAGTG GCTCCTGTGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCAATTCTCGTGCC TCAGCCTCTCAAGTAGCTGGGATTCCAGGCATGCACCCCACACCTGGCTATTTTTTTTTG TATTTAAATTTATTTTAATTTTTTTTTGAGGCAGAGTCTTGCTCTGTTGCCCAAGCTGGA GTGCAGTGGCATGATCTCAGCTCACTGCAACCTCCATCTCCCAGGCTCAAGCAATTCTCC TGCCTTGGCCCCCAGAGTAGCTGGGATTATAAGCACCTGCCACCATGCCCAGGTAATTTT TGCATGTTTAGTAGAGATGGGGTTTCACCATGTTGGCCAAGCTGGTCTCAAACTCTTGAC CTCANGTGATTTGCCCGCCTTGGCCTCTGAAAGTGCTGGGATACAGGCGTGAGCAACCGC GCCCAGCCCTATTTTTTTGTATTTTAGTAGAGACAGCCGTTCACACGTTGGCCAAGCTGG TCTCGAACTCCTGGCCTCAAGCCATCCACCCGCCTCAGCCTCCAAAAGTGCTGGGATTAC AGATGGGAGCCATGCCCCCTGCCCAAAGGCTATATTCTGGCTCTGAGTTTCCAAGACTGC TTTTAATCCCACTCTTTACATTAGATTAAAAAATTTTATCATTGGCAATCGGAACAATTA CTGCTCCTAGTCCN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_014263 |
| Insert Size | 3080 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_014263.2, NP_055078.1 |
| RefSeq Size | 3865 bp |
| RefSeq ORF | 2151 bp |
| Locus ID | 10730 |
| UniProt ID | Q96TA2 |
| Domains | Peptidase_M41, AAA, AAA |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] Transcript Variant: This variant (3) lacks an internal coding exon compared to transcript variant 1. However, it maintains the same reading frame, and encodes an isoform (3) that is missing a 57 aa segment compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201088 | YME1L1 (Myc-DDK-tagged)-Human YME1-like 1 (S. cerevisiae) (YME1L1), nuclear gene encoding mitochondrial protein, transcript variant 3 |
CNY 5,248.00 |
|
| RC201088L1 | Lenti ORF clone of Human YME1-like 1 (S. cerevisiae) (YME1L1), nuclear gene encoding mitochondrial protein, transcript variant 3, Myc-DDK-tagged |
CNY 7,648.00 |
|
| RC201088L2 | Lenti ORF clone of Human YME1-like 1 (S. cerevisiae) (YME1L1), nuclear gene encoding mitochondrial protein, transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RC201088L3 | Lenti ORF clone of Human YME1-like 1 (S. cerevisiae) (YME1L1), nuclear gene encoding mitochondrial protein, transcript variant 3, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC201088L4 | Lenti ORF clone of Human YME1-like 1 (S. cerevisiae) (YME1L1), nuclear gene encoding mitochondrial protein, transcript variant 3, mGFP tagged |
CNY 5,890.00 |
|
| RG201088 | YME1L1 (tGFP-tagged) - Human YME1-like 1 (S. cerevisiae) (YME1L1), nuclear gene encoding mitochondrial protein, transcript variant 3 |
CNY 4,370.00 |
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