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Sulfatase 2 (SULF2) (NM_198596) Human Untagged Clone
CAT＃: SC110537
SULF2 (untagged)-Human sulfatase 2 (SULF2), transcript variant 2
CNY 9,368.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HSULF-2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC110537 sequence for NM_198596 edited (data generated by NextGen Sequencing)
ATGGGCCCCCCGAGCCTCGTGCTGTGCTTGCTGTCCGCAACTGTGTTCTCCCTGCTGGGT GGAAGCTCGGCCTTCCTGTCGCACCACCGCCTGAAAGGCAGGTTTCAGAGGGACCGCAGG AACATCCGCCCCAACATCATCCTGGTGCTGACGGACGACCAGGATGTGGAGCTGGGTTCC ATGCAGGTGATGAACAAGACCCGGCGCATCATGGAGCAGGGCGGGGCGCACTTCATCAAC GCCTTCGTGACCACACCCATGTGCTGCCCCTCACGCTCCTCCATCCTCACCGGCAAGTAC GTCCACAACCACAACACCTACACCAACAATGAGAACTGCTCCTCGCCCTCCTGGCAGGCA CAGCACGAGAGCCGCACCTTTGCCGTGTACCTCAATAGCACTGGCTACCGGACAGCTTTC TTCGGGAAGTATCTTAATGAATACAACGGCTCCTACGTGCCACCCGGCTGGAAGGAGTGG GTCGGACTCCTTAAAAACTCCCGCTTTTATAACTACACGCTGTGTCGGAACGGGGTGAAA GAGAAGCACGGCTCCGACTACTCCAAGGATTACCTCACAGACCTCATCACCAATGACAGC GTGAGCTTCTTCCGCACGTCCAAGAAGATGTACCCGCACAGGCCAGTCCTCATGGTCATC AGCCATGCAGCCCCCCACGGCCCTGAGGATTCAGCCCCACAATATTCACGCCTCTTCCCA AACGCATCTCAGCACATCACGCCGAGCTACAACTACGCGCCCAACCCGGACAAACACTGG ATCATGCGCTACACGGGGCCCATGAAGCCCATCCACATGGAATTCACCAACATGCTCCAG CGGAAGCGCTTGCAGACCCTCATGTCGGTGGACGACTCCATGGAGACGATTTACAACATG CTGGTTGAGACGGGCGAGCTGGACAACACGTACATCGTATACACCGCCGACCACGGTTAC CACATCGGCCAGTTTGGCCTGGTGAAAGGGAAATCCATGCCATATGAGTTTGACATCAGG GTCCCGTTCTACGTGAGGGGCCCCAACGTGGAAGCCGGCTGTCTGAATCCCCACATCGTC CTCAACATTGACCTGGCCCCCACCATCCTGGACATTGCAGGCCTGGACATACCTGCGGAT ATGGACGGGAAATCCATCCTCAAGCTGCTGGACACGGAGCGGCCGGTGAATCGGTTTCAC TTGAAAAAGAAGATGAGGGTCTGGCGGGACTCCTTCTTGGTGGAGAGAGGCAAGCTGCTA CACAAGAGAGACAATGACAAGGTGGACGCCCAGGAGGAGAACTTTCTGCCCAAGTACCAG CGTGTGAAGGACCTGTGTCAGCGTGCTGAGTACCAGACGGCGTGTGAGCAGCTGGGACAG AAGTGGCAGTGTGTGGAGGACGCCACGGGGAAGCTGAAGCTGCATAAGTGCAAGGGCCCC ATGCGGCTGGGCGGCAGCAGAGCCCTCTCCAACCTCGTGCCCAAGTACTACGGGCAGGGC AGCGAGGCCTGCACCTGTGACAGCGGGGACTACAAGCTCAGCCTGGCCGGACGCCGGAAA AAACTCTTCAAGAAGAAGTACAAGGCCAGCTATGTCCGCAGTCGCTCCATCCGCTCAGTG GCCATCGAGGTGGACGGCAGGGTGTACCACGTAGGCCTGGGTGATGCCGCCCAGCCCCGA AACCTCACCAAGCGGCACTGGCCAGGGGCCCCTGAGGACCAAGATGACAAGGATGGTGGG GACTTCAGTGGCACTGGAGGCCTTCCCGACTACTCAGCCGCCAACCCCATTAAAGTGACA CATCGGTGCTACATCCTAGAGAACGACACAGTCCAGTGTGACCTGGACCTGTACAAGTCC CTGCAGGCCTGGAAAGACCACAAGCTGCACATCGACCACGAGATTGAAACCCTGCAGAAC AAAATTAAGAACCTGAGGGAAGTCCGAGGTCACCTGAAGAAAAAGCGGCCAGAAGAATGT GACTGTCACAAAATCAGCTACCACACCCAGCACAAAGGCCGCCTCAAGCACAGAGGCTCC AGTCTGCATCCTTTCAGGAAGGGCCTGCAAGAGAAGGACAAGGTGTGGCTGTTGCGGGAG CAGAAGCGCAAGAAGAAACTCCGCAAGCTGCTCAAGCGCCTGCAGAACAACGACACGTGC AGCATGCCAGGCCTCACGTGCTTCACCCACGACAACCAGCACTGGCAGACGGCGCCTTTC TGGACACTGGGGCCTTTCTGTGCCTGCACCAGCGCCAACAATAACACGTACTGGTGCATG AGGACCATCAATGAGACTCACAATTTCCTCTTCTGTGAATTTGCAACTGGCTTCCTAGAG TACTTTGATCTCAACACAGACCCCTACCAGCTGATGAATGCAGTGAACACACTGGACAGG GATGTCCTCAACCAGCTACACGTACAGCTCATGGAGCTGAGGAGCTGCAAGGGTTACAAG CAGTGTAACCCCCGGACTCGAAACATGGACCTGGATGGAGGAAGCTATGAGCAATACAGG CAGTTTCAGCGTCGAAAGTGGCCAGAAATGAAGAGACCTTCTTCCAAATCACTGGGACAA CTGTGGGAAGGCTGGGAAGGTTAA Clone variation with respect to NM_198596.2 291 t=>c >OriGene 5' read for NM_198596 unedited
NGTCAGATTTGTATACGACTCACTATAGGCGGCCGCGATTCGGCACCAGAGACGCAACTT GAGACTCCCGCATCCCAAAAAAAGCACCAGATCAGCAAAAAAAGAAGATGGGCCCCCCGA GCCTCGTGCTGTGCTTGCTGTCCGCAACTGTGTTCTCCCTGCTGGGTGGAAGCTCGGCCT TCCTGTCGCACCACCGCCTGAAAGGCAGGTTTCAGAGGGACCGCAGGAACATCCGCCCCA ACATCATCCTGGTGCTGACGGACGACCAGGATGTGGAGCTGGGTTCCATGCAGGTGATGA ACAAGACCCGGCGCATCATGGAGCAGGGCGGGGCGCACTTCATCAACGCCTTCGTGACCA CACCCATGTGCTGCCCCTCACGCTCCTCCATCCTCACCGGCAAGTACGTCCACAACCACA ACACCTACACCAACAATGAGAACTGCTCCTCGCCCTCCTGGCAGGCACAGCACGAGAGCC GCACCTTTGCCGTGTACCTCAATAGCACTGGCTACCGGACAGCTTTCTTCGGGAAGTATC TTAATGAATACAACGGCTCCTACGTGCCACCCGGCTGGAAGGAGTGGGTCGGACTCCTTA AAAACTCCCGCTTTTATAACTACACGCTGTGTCGGAACGGNGTGAAAGAGAAGCACGGCT CCGACTACTCCAAGGATTACCTCACAGACCTCATCACCAATGACAGCGTGAGCTTCTTCC GCACGTCCAAGAAGATGTACCCGCACAGGCCAGTCCTCATGGTCATCAGCCATGCAGCCC CCCACGGCCCTGAGATCAGCCCCACATATCACGCCTCTTCCAACGCATCTCACACTCACG CCGAGCTACACTACGCGCCCAACCGGACAACACTGNATCATGCGCTACACGGNGCCCATG AAGCCCATCCACTGGNAATCACCACATGCTCAGCGAAGCGCTTGCAGACCT >OriGene 3' read for NM_198596 unedited
CATTTGGACCGCGCCGCATTCTANGATCGATTTTTTTTTTTTTTTTTTTTTTTTTTCTTT TACACTGGCCACAGAGCGTTTATTGACACCACCACTCCTGAAAATTGGGATTTCTTATTA GGTTCCCCTAAAAGTTCCCATGTTGATTACATGTAAATAGTCACATATATACAATGAAGG CAGTTTCTTCAAAGGCAACCAGGGTTTATAGTGCTAGGTAAATGTCATCTCTTTTGTGCT ACTGACTCATTGTCAAACGTCTCTGCACTGTTTTCAGCCTCTCCACGTTGCCTCTGTCCT GCTTCTTAGTTCCTTCTTTGTGACAAACCAAAAGAATAAGAGGATTTAGAACAGGACTGC TTTTCCCCTATGATTTAAAAATTCCAATGACTTTCGCCCTTGGGAGAAATTTCCAAGGAA ATCTCTCTCGCTCGCTCTCTCCGTTTTCCTTTGTGAGCTTCTGGGGGAGGGTTAGTGGTG ACTTTTTGATACGAAAAAATGCATTTTGTGCAGCTGGTGAGGTATAATCCAAAGCAAAAG CAGGGGCAAAAATGGACTTCCTGAAGTTATCTCTGCTCCTGCTGGTTATCCTCCAGAATC TGTCATGTTGACTGAAAGTGCGTGCTTGCTTTCTCAGGCCTCCTGGCCAATAGCACAGGT CTGCTGGAAATCACCCACATGGTTTTTCATTGCCTGTGCAGTCAGGTGATGCCTCTATGT TTTTGGAGGTCCACCTCTGTTGTTTTCTTAACTTTCCCACCCTTCCCAAGTTTGTCCAAT GATTTGGAAGAAAGTCCCTTCATTTCTGCCCATTTCAACGCCTGAAACTGCCTGATTGCT CAAAACTTCCTCCATCTTTAAATCCCAGGCCATGGTTCNAGTCCGGGGGTTACACTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_198596 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_198596.1, NP_940998.1 |
| RefSeq Size | 4239 bp |
| RefSeq ORF | 2559 bp |
| Locus ID | 55959 |
| UniProt ID | Q8IWU5 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008] Transcript Variant: This variant (2) differs in the 5' UTR and includes an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221582 | SULF2 (Myc-DDK-tagged)-Human sulfatase 2 (SULF2), transcript variant 2 |
CNY 9,360.00 |
|
| RC221582L3 | Lenti ORF clone of Human sulfatase 2 (SULF2), transcript variant 2, Myc-DDK-tagged |
CNY 11,120.00 |
|
| RC221582L4 | Lenti ORF clone of Human sulfatase 2 (SULF2), transcript variant 2, mGFP tagged |
CNY 11,120.00 |
|
| RG221582 | SULF2 (tGFP-tagged) - Human sulfatase 2 (SULF2), transcript variant 2 |
CNY 10,960.00 |
|
| SC328022 | SULF2 (untagged)-Human sulfatase 2 (SULF2) transcript variant 2 |
CNY 10,168.00 |
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