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SCDGFB (PDGFD) (NM_033135) Human Untagged Clone
CAT＃: SC110642
PDGFD (untagged)-Human platelet derived growth factor D (PDGFD), transcript variant 2
CNY 3,656.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | IEGF; MSTP036; SCDGF-B; SCDGFB |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_033135, the custom clone sequence may differ by one or more nucleotides
ATGCACCGGCTCATCTTTGTCTACACTCTAATCTGCGCAAACTTTTGCAGCTGTCGGGACACTTCTGCAA CCCCGCAGAGCGCATCCATCAAAGCTTTGCGCAACGCCAACCTCAGGCGAGATGACTTGTACCGAAGAGA TGAGACCATCCAGGTGAAAGGAAACGGCTACGTGCAGAGTCCTAGATTCCCGAACAGCTACCCCAGGAAC CTGCTCCTGACATGGCGGCTTCACTCTCAGGAGAATACACGGATACAGCTAGTGTTTGACAATCAGTTTG GATTAGAGGAAGCAGAAAATGATATCTGTAGGTATGATTTTGTGGAAGTTGAAGATATATCCGAAACCAG TACCATTATTAGAGGACGATGGTGTGGACACAAGGAAGTTCCTCCAAGGATAAAATCAAGAACGAACCAA ATTAAAATCACATTCAAGTCCGATGACTACTTTGTGGCTAAACCTGGATTCAAGATTTATTATTCTTTGC TGGAAGATTTCCAACCCGCAGCAGCTTCAGAGACCAACTGGGAATCTGTCACAAGCTCTATTTCAGGGGT ATCCTATAACTCTCCATCAGTAACGGATCCCACTCTGATTGCGGATGCTCTGGACAAAAAAATTGCAGAA TTTGATACAGTGGAAGATCTGCTCAAGTACTTCAATCCAGAGTCATGGCAAGAAGATCTTGAGAATATGT ATCTGGACACCCCTCGGTATCGAGGCAGGTCATACCATGACCGGAAGTCAAAAGTTGACCTGGATAGGCT CAATGATGATGCCAAGCGTTACAGTTGCACTCCCAGGAATTACTCGGTCAATATAAGAGAAGAGCTGAAG TTGGCCAATGTGGTCTTCTTTCCACGTTGCCTCCTCGTGCAGCGCTGTGGAGGAAATTGTGGCTGTGGAA CTGTCAACTGGAGGTCCTGCACATGCAATTCAGGGAAAACCGTGAAAAAGTATCATGAGGTATTACAGTT TGAGCCTGGCCACATCAAGAGGAGGGGTAGAGCTAAGACCATGGCTCTAGTTGACATCCAGTTGGATCAC CATGAACGATGTGATTGTATCTGCAGCTCAAGACCACCTCGATAA >OriGene 5' read for NM_033135 unedited
GGTTCAAATATTTGTATACGACTCACTATTAGGGCGGCCGCGATTCGGCACGAGGCAAGG AAGTGCGGCACCCACACGCGCTCGNGAAGTTCAGCATGCAGGAAGTTTGGGGAGAGCTCG GCGATTAGCACAGCGACCCGGGCCAGCGCAGGGCGAGCGCAGGCGGCGAGAGCGCAGGGC GGCGCGGCGTCGGTCCCGGGAGCAGAACCCGGCTTTTTCTTGGAGCGACGCTGTCTCTAG TCGCTGATCCCAAATGCACCGGCTCATCTTTGTCTACACTCTAATCTGCGCAAACTTTTG CAGCTGTCGGGACACTTCTGCAACCCCGCAGAGCGCATCCATCAAAGCTTTGCGCAACGC CAACCTCAGGCGAGATGACTTGTACCGAAGAGATGAGACCATCCAGGTGAAAGGAAACGG CTACGTGCAGAGTCCTAGATTCCCGAACAGCTACCCCAGGAACCTGCTCCTGACATGGCG GCTTCACTCTCAGGAGAATACACGGATACAGCTAGTGTTTGACAATCAGTTTGGATTAGA GGAAGCAGAAAATGATATCTGTAGGTATGATTTTGTGGAAGTTGAAGATATATCCGAAAC CAGTACCATTATTAGAGGACGATGGTGTGGACACAAGGAAGTTCCTCCAAGGATAAAATC AAGAACGAACCAAATTAAAATCACATTCAAGTCCGATGACTACTTTGTGGCTAAACCTGG ATTCAAGATTTATTATTCTTTGCTGGAAGATTTCCACCCGCAGCAGCTTCAGAGACCAAC TGGGAATCTGTNCACAGCTCTATTTCAGGNGTATNNCTATACTCTNCATCAGTNACGGGA TCCACTCTGATTGCGGATGCTCTGGACAAAAAAATGCAGAATTGATACAGTGGAGATCTG CTCAGTACTTCATCCAGAGC >OriGene 3' read for NM_033135 unedited
TTTGGACCGGCGGCCGCAATCTTTGATCGAGTTTTTTTTTTTTTTTTTTGTTCAAAAGCA TATTTATTTTTCATGAAGATAAGAGGCATATTACATTCGCTATAGAAAATGCTATGAGAG GAAAAAGCTGCATGTTACCGATATGACAAAAAACATAAAAAACTCTACTTATGAAAGTGT TTTGCCCTATAAGAACATATTCAATAAAAGGCATTATTCCAGGTGAATGAGCCATGCGGA AATGTGGATTTATTAGGGTTTGTTTTGAAATGTAATTTGTACGGCCAGCTTTTTATTCCT TTGATGGCTATCAAATAGATTTATTGGCTACATGTTAGAAGTGCAAAAGATAACAGGTAA CCAAGGGAGAAGTTTTAATAAAACTCTCAGGAAAGGCAAAGAAAAGTGAGTGAATATGCC TGCTTACATTTCAGCTAATAAATAAAAAGTGCAGATAGGGCTTTAACTGAAAACCTTGCT GGTTATTGCAGCCTGGAAGGTTTATTGAAAACTGGGTAGAACACTCTCATTTTTTATATT TACAGCTACATTGTGAGCTGTTCAGGTTAGAGTGATGTAACGTTCATTTTGACTTTGTTA CAGGAAACTGATGTTTTCACAGGAAACTTGCAAAGCAGTTATGAAGAGGAAGAGCGTTCT TAATTATTAGTGTCTGCCTGAGCTATTTCTGATTGGGTTCTGGGATTTTTAGAGAATTGA CAATAGAGTATTTAAATTTACCACTCCCCTCTGGAGTAAAACATTAGACCCTTTTAGAAA GTTTTAAAAGTACTTTTCAATAACCGAGAACTTTCATTCTAAATAACTGGGAAGATTGCC CTGCTTAAGAAAGTTGAACTGGACCTGAAACCCCTTCCTTAAAATCTAAGTTATTTAGGC ACTTATTTAACCTGGGACTTTACCACCCTGTACCCCAAACTGGTTTGATTAAGAAACCCC C |
| Restriction Sites | NotI-NotI |
| ACCN | NM_033135 |
| Insert Size | 4000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_033135.2, NP_149126.1 |
| RefSeq Size | 3979 bp |
| RefSeq ORF | 1095 bp |
| Locus ID | 80310 |
| UniProt ID | Q9GZP0 |
| Domains | CUB |
| Protein Families | Druggable Genome, Secreted Protein |
| Protein Pathways | Focal adhesion, Gap junction, Melanoma, Prostate cancer, Regulation of actin cytoskeleton |
| Gene Summary | The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Down-regulation of Platelet-Derived Growth Factor-D Inhibits Cell Growth and Angiogenesis through Inactivation of Notch-1 and Nuclear Factor-B Signaling
,Zhiwei Wang, Dejuan Kong, Sanjeev Banerjee, Yiwei Li, N. Volkan Adsay, James Abbruzzese, and Fazlul H. Sarkar,
Cancer Res., Dec 2007; 67: 11377 - 11385
[PDGFD]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205520 | PDGFD (Myc-DDK-tagged)-Human platelet derived growth factor D (PDGFD), transcript variant 2 |
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| RC205520L3 | Lenti ORF clone of Human platelet derived growth factor D (PDGFD), transcript variant 2, Myc-DDK-tagged |
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| RC205520L4 | Lenti ORF clone of Human platelet derived growth factor D (PDGFD), transcript variant 2, mGFP tagged |
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| RG205520 | PDGFD (tGFP-tagged) - Human platelet derived growth factor D (PDGFD), transcript variant 2 |
CNY 5,256.00 |
