Syndecan 2 (SDC2) (NM_002998) Human Untagged Clone
CAT#: SC111011
SDC2 (untagged)-Human syndecan 2 (SDC2)
CNY 2,400.00
CNY 2,950.00
Cited in 1 publication. |
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CD362; HSPG; HSPG1; SYND2 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC111011 sequence for NM_002998 edited (data generated by NextGen Sequencing)
ATGCGGCGCGCGTGGATCCTGCTCACCTTGGGCTTGGTGGCCTGCGTGTCGGCGGAGTCG AGAGCAGAGCTGACATCTGATAAAGACATGTACCTTGACAACAGCTCCATTGAAGAAGCT TCAGGAGTGTATCCTATTGATGACGATGACTACGCTTCTGCGTCTGGCTCGGGAGCTGAT GAGGATGTAGAGAGTCCAGAGCTGACAACATCTCGACCACTTCCAAAGATACTGTTGACT AGTGCTGCTCCAAAAGTGGAAACCACGACGCTGAATATACAGAACAAGATACCTGCTCAG ACAAAGTCACCTGAAGAAACTGATAAAGAGAAAGTTCACCTCTCTGACTCAGAAAGGAAA ATGGACCCAGCCGAAGAGGATACAAATGTGTATACTGAGAAACACTCAGACAGTCTGTTT AAACGGACAGAAGTCCTAGCAGCTGTCATTGCTGGTGGAGTTATTGGCTTTCTCTTTGCA ATTTTTCTTATCCTGCTGTTGGTGTATCGCATGAGAAAGAAGGATGAAGGAAGCTATGAC CTTGGAGAACGCAAACCATCCAGTGCTGCTTATCAGAAGGCACCTACTAAGGAGTTTTAT GCGTAA Clone variation with respect to NM_002998.3 >OriGene 5' read for NM_002998 unedited
GTTAGAAATTATGTAATACGACTCACTATAGGGCGGCCGCGAATCGGCACGAGCAGCCGC GGAGCCAGTGGCCCCGCTTGGACGCGCTGCTCTCCAGATACCCCCGGAGCTCCAGCCGCG CGGATCGCGCGCTCCCGCCGCTCTGCCCCTAAACTTCTGCCGTAGCTCCCTTTCAAGCCA GCGAATTTATTCCTTAAAACCAGAAACTGAACCTCGGCACGGGAAAGGAGTCCGCGGAGG AGCAAAACCACAGCAGAGCAAGAAGAGCTTCAGAGAGCAGCCTTCCCGGAGCACCAACTC CGTGTCGGGAGTGCAGAAACCAACAAGTGAGAGGGCGCCGCGTTCCCGGGGCGCAGCTGC GGGCGGCGGGAGCAGGCGCAGGAGGAGGAAGCGAGCGCCCCCGAGCCCCGAGCCCGAGTC CCCGAGCCTGAGCCGCAATCGCTGCGGTACTCTGCTCCGGATTCGTGTGCGCGGGCTGCG CCGAGCGCTGGGCAGGAGGCTTCGTTTTGCCCTGGTTGCAAGCAGCGGCTGGGAGCAGCC GGTCCCTGGGGAATATGCGGCGCGCGTGGATCCTGCTCACCTTGGGCTTGGTGGCCTGCG TGTCGGCGGAGTCGAGAGCAGAGCTGACATCTGATAAAGACATGTACCTTGACAACAGCT CCATTGAAGAAGCTTCAGGAGTGTATCCTATTGATGACGATGACTACGCTTCTGCGTCTG GCTCGGGAGCTGATGAGGATGTAGAGAGTCCAGAGCTGACAACATCTCGACCACTTCCAA AGATACTGTTGACTAGTGCTGCTCCAAAGTGGAAACCACGACGCTGAATATACAGAACAA GATACCTGCTCAGACAAAGTCACCTGAAGAAACTGATNAAGAGAAANGTCACCTCTCTGA CTCAGAAGGNAAANTGGACCAGNCGCAGAGATACAAAGTGTATACTGAGAAACCTCA >OriGene 3' read for NM_002998 unedited
NNTTTTTGCTCTGGACCCGCGGCCGCATNCTAGNGATCGGTTTTTTTTTTTTTTTTTTAG GCCACATGATTTATTCAGTAGTTTTTATGTTCCCAAATACAATTTATGTCTATTCATAAG ACTACAAAAGTTACCATTAGAATTGTCTGTGCTTATAAAATACCAACTTTTTTTTTAAAC TGTTACATATACTCATTAACACCAGTCTGCAACAAGTTACATAGAATCAGAGGCACTTCA AAGGCTTAAAAAGACGTTTACAACTTAAATGCATTTTTAAGAACAAAAACTGATTTTTCT TTAAACCTCTACTCGTACCTTCAAATTGCAAGAAATTAACAAATACAGTGGCCAAAGGAA TCTGCAGCAACTTCTTAAAATACTGTTAACATCTTTGGGTTTGCTGAGGCTTGTCAGTAA CTTACATCAAATCCTCCCAAAAGAAGATCTGATTAGATAGATATGACTAAACGGTTTTGT AGTAATAATCCAATTTTACACATTAATTTGCTGTTGCAAATCTGCCCAAAGCTACAGGTA ATGAAAAATAAAGCAAGTGTAAAATGGATAGTCTGACACTTAAAAATTTATACAAAGCGG AAGTTAAAGTTTACATATTTTGAAAATCACATATCCCCTAAATTACCCTTATCTGAATTT TCCCAAAGACAAATTGCCCCATGACAGCCTACAAAAAGCATATGGCTTTGGCTTTAAGGG CCCCCTCAAGGTAGGGCATAACGATAGGAAGGGCACCTCGCATATCTTACCAAAGTCTGA CCACCTTGTTCAGGTCATTCTGACACATGCTGACACAAAGGAAACACTTTTTCTCTTTGA TCTCTAGGAAAACGAAACTTTTTGGTCTTTGCCTCTACACTCCAACCCCTCCCTGTACCC ACTAGTTTCCACACCAATAACTT |
Restriction Sites | NotI-NotI |
ACCN | NM_002998 |
Insert Size | 2210 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_002998.3, NP_002989.2 |
RefSeq Size | 3485 bp |
RefSeq ORF | 606 bp |
Locus ID | 6383 |
UniProt ID | P34741 |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Cell adhesion molecules (CAMs), ECM-receptor interaction |
Gene Summary | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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DNA methyltransferase-mediated transcriptional silencing in malignant glioma: a combined whole-genome microarray and promoter array analysis
,G Foltz, J -G Yoon, H Lee, T C Ryken, Z Sibenaller, M Ehrich, L Hood, A Madan,
Oncogene (25 May 2009) doi:10.1038/onc.2009.122
[SDC2]
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