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CBF1 interacting corepressor (CIR1) (NM_004882) Human Untagged Clone
CAT＃: SC111118
CIR1 (untagged)-Human corepressor interacting with RBPJ, 1 (CIR1)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CIR |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111118 sequence for NM_004882 edited (data generated by NextGen Sequencing)
ATGGGGAAATCCTTCGCCAACTTCATGTGCAAGAAAGACTTTCATCCTGCCTCCAAATCC AATATCAAAAAAGTATGGATGGCAGAACAGAAAATATCATATGATAAGAAGAAACAAGAA GAATTGATGCAGCAATATCTTAAAGAACAAGAATCATATGATAATAGATTGCTTATGGGA GATGAACGTGTAAAGAATGGCCTTAATTTCATGTATGAAGCCCCACCAGGAGCTAAAAAA GAAAACAAAGAGAAAGAAGAAACAGAAGGAGAGACCGAATACAAATTTGAATGGCAGAAA GGAGCCCCACGAGAAAAATATGCCAAAGATGACATGAACATCAGAGATCAGCCCTTTGGT ATTCAGGTTCGAAATGTGAGGTGCATTAAATGTCACAAATGGGGTCATGTCAACACAGAT CGAGAATGTCCTTTGTTTGGTCTTTCTGGAATCAATGCAAGTTCGGTTCCCACTGATGGC TCAGGGCCATCGATGCACCCCTCGGAGCTAATAGCGGAGATGAGAAACAGTGGGTTTGCA CTGAAACGAAATGTACTGGGGAGAAACTTGACCGCAAATGATCCATCACAGGAGTATGTT GCAAGTGAGGGTGAAGAAGATCCAGAAGTTGAATTTTTAAAGTCACTAACAACCAAACAA AAACAGAAACTTCTCAGGAAATTAGATCGACTGGAGAAGAAAAAAAAGAAAAAAGATAGA AAAAAGAAAAAGTTTCAGAAGAGCAGAAGTAAACACAAAAAACATAAGTCCTCTTCTTCC TCATCTTCCTCCTCCTCCTCCTCTTCCTCTACTGAGACTTCAGAAAGCAGTAGTGAGAGT GAGAGTAACAATAAAGAAAAAAAAATACAAAGGAAGAAAAGAAAGAAAAACAAGTGTTCA GGGCATAACAACAGTGATTCTGAAGAGAAGGACAAGTCTAAGAAGAGAAAGCTTCATGAA GAACTTTCTAGCAGTCACCATAACCGGGAAAAAGCCAAGGAAAAGCCCAGGTTCTTAAAA CACGAGAGTTCTAGGGAGGACAGCAAATGGAGCCATTCTGATTCTGACAAAAAGTCCAGA ACCCATAAACATAGCCCAGAGAAGAGAGGCTCTGAAAGAAAGGAGGGGAGCAGCAGAAGC CACGGCAGGGAGGAAAGGAGCCGGAGAAGCCGGAGCAGAAGTCCTGGTAGTTACAAGCAA AGGGAGACAAGGAAACGGGCACAGCGAAATCCTGGTGAAGAGCAAAGCAGAAGAAATGAC AGCAGAAGCCATGGCACAGACTTGTATAGAGGAGAAAAAATGTACAGAGAGCACCCAGGA GGTACACATACTAAAGTGACACAAAGAGAATGA Clone variation with respect to NM_004882.3 >OriGene 5' read for NM_004882 unedited
AGGATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCAGATCTAG CCCCTGCTTTCCCTAGTTCCAGTTCCAAGATGGGGAAATCCTTCGCCAACTTCATGTGCA AGAAAGACTTTCATCCTGCCTCCAAATCCAATATCAAAAAAGTATGGATGGCAGAACAGA AAATATCATATGATAAGAAGAAACAAGAAGAATTGATGCAGCAATATCTTAAAGAACAAG AATCATATGATAATAGATTGCTTATGGGAGATGAACGTGTAAAGAATGGCCTTAATTTCA TGTATGAAGCCCCACCAGGAGCTAAAAAAGAAAACAAAGAGAAAGAAGAAACAGAAGGAG AGACCGAATACAAATTTGAATGGCAGAAAGGAGCCCCACGAGAAAAATATGCCAAAGATG ACATGAACATCAGAGATCAGCCCTTTGGTATTCAGGTTCGAAATGTGAGGTGCATTAAAT GTCACAAATGGGGTCATGTCAACACAGATCGAGAATGTCCTTTGTTTGGTCTTTCTGGAA TCAATGCAAGTTCGGTTCCCACTGATGGCTCAGGGCCATCGATGCACCCCTCGGAGCTAA TAGCGGAGATGAGAAACAGTGGGTTTGCACTGAAACGAAATGTACTGGGGAGAAACTTGA CCGCAAATGATCCATCACAGGAGTATGTTGCAAGTGAGGGTGAAGAAGATCCATCACAGG AGTATGTTGCAAGTGAGGGTGAAGAAGATCCAGAAAGTGAATTNTTAAGTCACTAACACC AAACAAAACAGAAACTTCTCAGGAANATAGATCGACTGGAGAAAGAAAAAAAGAAAAAGA TTGANAAAGAAAAGTTTCAGAAGAGCAGAAGTAACACAAAAACATAAGNCCTCTTNCTTC TCATCTNCCCCTCCTCCTNCTCTTNCTCTACTGAAACTTCGAAAGCAGTAGTGAGAGTGA NAAGTACACTAAGAC >OriGene 3' read for NM_004882 unedited
CGCGGCCGCAATTTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTCAAGGAACTGTCATTCT TTTAATGATGTTTCAGAACAAAAAAAATGTCACAGAGTTATATGCGGTTTTTATCTGGTA TGGGGAACAAGAAACAGTTACCAACAGAAAATATTTCCACAGCCCCAAAATAGCTTACTT ACAAATATTTGCAAAATTCATTCTCATAGTACTCATGTAGTTTTGTACTTGAATTGACAG TCTAGAGATGAAAAATTAAAATTGAGCTTTTTTATTAGAAAGACAACAGTACATAATTTA CCCCTTGCTAAAGGTATTCAATAAAAAAGTGGAGATATTTTTATTCCCAGGTAATTGTCA CATACAGTCTTTCTTCTCTACTTCTGCTTCATTCTCTTTGGGTCACTTTAGTATGTGTAC CTCCTGGGGGCTCTCTGTACATTTTTTCTCCTCTATACAAGTCTGTGCCATGGCTTCTGC TGTCATTTCTTCTGCTTTGCTCTTCACCAGGATTTCGCTGTGCCCGTTTCCTTGTCTCCC TTTGCTTGTAACTACCAGGACTTCTGCTCCGGCTTCTCCGGCTCCTTTCCTCCCTGCCGG GGCTTCTGCTGCTCCCCTCCTTTCTTTCAGAGCCTCTCTTCTCTGGGCTATGTTTATGGG TTCTGGACTTTTTGTCAGAATCAGAATGGCTCCATTTGCTGGCCTCCCTAGAACTCTCGT NGTTTAAGAACCTGGNGCTTTCCTTGGCTTTTTCCGGTTATGGGGACTGCTANAAAGTTC TTCATGAAAGCTTCTCCNCTTAGACTTGCCCTTCTCTCCAGATCACTGTGGTATGCCCTG AACACTTGGTTTTCTTTCTTTCTTCCTTGGNNATTTTTTTCCTTATGGAACCCTACTCTA CTACGGCTTCTGAAGCCTCANNGAGGAAAGGAGGGGGGGAGAAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004882 |
| Insert Size | 1870 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004882.3, NP_004873.3 |
| RefSeq Size | 1809 bp |
| RefSeq ORF | 1353 bp |
| Locus ID | 9541 |
| UniProt ID | Q86X95 |
| Protein Families | Transcription Factors |
| Protein Pathways | Notch signaling pathway |
| Gene Summary | May modulate splice site selection during alternative splicing of pre-mRNAs (By similarity). Regulates transcription and acts as corepressor for RBPJ. Recruits RBPJ to the Sin3-histone deacetylase complex (HDAC). Required for RBPJ-mediated repression of transcription.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC208486 | CIR1 (Myc-DDK-tagged)-Human corepressor interacting with RBPJ, 1 (CIR1) |
CNY 3,656.00 |
|
| RC208486L3 | Lenti-ORF clone of CIR1 (Myc-DDK-tagged)-Human corepressor interacting with RBPJ, 1 (CIR1) |
CNY 5,890.00 |
|
| RC208486L4 | Lenti-ORF clone of CIR1 (mGFP-tagged)-Human corepressor interacting with RBPJ, 1 (CIR1) |
CNY 5,890.00 |
|
| RG208486 | CIR1 (tGFP-tagged) - Human corepressor interacting with RBPJ, 1 (CIR1) |
CNY 5,256.00 |
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