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ORAI3 (NM_152288) Human Untagged Clone
CAT＃: SC111493
ORAI3 (untagged)-Human ORAI calcium release-activated calcium modulator 3 (ORAI3)
CNY 3,600.00
| Cited in 5 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | TMEM142C |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111493 sequence for NM_152288 edited (data generated by NextGen Sequencing)
ATGAAGGGCGGCGAGGGGGACGCGGGCGAGCAGGCCCCGCTGAACCCTGAGGGCGAGAGC CCTGCAGGCTCGGCCACGTACCGGGAGTTCGTGCACCGCGGCTACCTGGACCTCATGGGG GCCAGTCAGCACTCGCTGCGGGCGCTCAGCTGGCGCCGCCTCTACCTCAGCCGGGCCAAG CTCAAAGCTTCCAGCCGCACGTCTGCCTTGCTCTCGGGCTTCGCCATGGTGGCCATGGTG GAGGTGCAGCTGGAGAGTGACCACGAGTACCCACCAGGCCTGCTGGTGGCCTTCAGTGCC TGCACCACCGTGCTGGTGGCTGTGCACCTCTTTGCACTCATGGTCTCCACGTGTCTGCTG CCCCACATTGAAGCTGTGAGCAACATCCACAACCTCAACTCTGTCCACCAGTCGCCACAC CAGAGACTGCACCGCTACGTGGAGCTGGCCTGGGGCTTCTCCACTGCCCTGGGCACCTTT CTCTTCCTTGCTGAAGTTGTCCTGGTTGGTTGGGTCAAGTTTGTGCCCATTGGGGCTCCC TTGGACACACCGACCCCCATGGTGCCCACATCCCGGGTGCCCGGGACTCTGGCACCAGTG GCTACCTCCCTTAGTCCAGCTTCCAATCTCCCACGGTCCTCTGCGTCTGCAGCACCGTCC CAGGCTGAGCCAGCCTGCCCACCCCGGCAAGCCTGTGGTGGTGGTGGGGCCCATGGGCCA GGCTGGCAAGCAGCCATGGCCTCCACAGCCATCATGGTACCCGTGGGGCTCGTGTTTGTG GCCTTTGCCCTGCATTTCTACCGCTCCTTGGTGGCACACAAGACAGACCGCTACAAGCAG GAACTAGAGGAACTGAATCGCCTGCAGGGGGAGCTGCAGGCTGTGTGA Clone variation with respect to NM_152288.2 >OriGene 5' read for NM_152288 unedited
GCGCATATGAAACCGATTCACGATAGGCGGAACGCCAATTCGCACGAGCCTGGGCGCTTG CCGCCTGCATCCTGCTCGCCCTGTCTGGGAATGGGGCCGCCCCCGGGCTTGGGCCGGCCC GGCTGGGGCCCCCGAGGCGCTTCCGCCCCGTAGTGACCGCCTGGTGCCGCCCCCCCCCCA GGATGAAGGGCGGCGAGGGGGACTCTGGTGGCTGGCCCCGCTGAACCCTGTTGGCGAGAG CCCTGCAGGCTCGGCCACGTACCGGGAGTTCGTGCACCGCGGCTACCTGGACCTCATGGG GGCCAGTCAGCACTCGCTGCGGGCGCTCAGCTGGCGCCGCCTCTACCTCAGCCGGGCCAA GCTCAAAGCTTCCAGCCGCACGTCTGCCTTGCTCTCGGGCTTCGCCATGGTGGCCATGGT GGAGGTGCAGCTGGAGAGTGACCACGAGTACCCACCAGGCCTGCTGGTGGCCTTCAGTGC CTGCACCACCGTGCTGGTGGCTGTGCACCTCTTTGCACTCATGGTCTCCACGTGTCTGCT GCCCCACATTGAAGCTGTGAGCAACATCCACAACCTCAACTCTGTCCACCAGTCGGCACA CCAGAGACTGCACCGCTACCTGGAGCTGGCCTGGGGCTTCTCCACTGCCCTGGGCACCTT TCTCTTCTTGCTGAAATTGCCCTGGTTGGCTGGGTAAAGTTTGAGCCCATTGGGGCTTCC TTGGGACCACCGGACCCCCTGGGGCCCACATCCCGGGGGCCCGGGCCCCTGGGACAAGGG GGCTCCATCCCTTGGTCCAGCTTTCAATCCGCCAAGGGCCCTCTGTGTTTGTATCACGTC CCCAGGCTGAGCCAGGCCGGCCCACACCGGCAAGCCTGTGGTTGTGGGGGGGCCCCATGG GCCAGGCTTGGATAAAACCTTGACCTAAAAACCTCACAGGAAACCATGGGAGTTCGTGTA GGGCAC >OriGene 3' read for NM_152288 unedited
GGACCTCCTACGGATTCCTACCACTTTAGGTGCTCCAAATCACTGTCGAAGACTTTGTAT TTCAAGGGCTACAGACTGGACCTTCTCCCTTAAAACCTCCTTACCCAACCCTTGCTAAGG ACTCAGGCCTGGGGCAGAGGCTGTCAGTCTCTAAAGACCCCAGCCCTGGACCAGGACGGG GGAGAACAAGTTTGGTGCATAGCGTGGGGCTAGGGCAGTGGGTCAGGCACCATCCCTTCT GCAAGTGGCCACAGGTCACCACAGTGGGGGAAGGTGGGGAGCTTGAACCTCCAAAGATAG GTTCATTGTAGGAAAAGCTAGACCAATGCCTTGGGTAGAAACACCCAAATCCCTCTACAA CAACTAAAGCAAGAATGTGGAACCCATCGAAATCTTCCCCCAAAATGCCAACCATAAAAT AGATTCTACAGAAATAAAGAAAGGAATCCCAGCACTTTGGGAGGCCGAGGCGGGAGGTTC ACTTGAGCCCAGGAGTTTGAGACCAGCCTGGGAACAGCGAAACCCCGTCTCTACAAAAAA ATTAGTCCGGTGTGGCAGCCCACACCTGTAGTACCAGCTACTCACTACCTGGGAGGCTGT GGTGGGAGCATCTTTTGAGCCCGGAAGGTCGAGGCTACCGTGAGCTGTGACTGTATCACT ACACTCCAGCCTGGGAAACAGACTGTCCTCAAAAAAAAAAAAAAATTGAACGCGCAATTG GGCTGCCTTCTGACCTTCACATCCTGGATAGGAATGGAAATGGGGGCTTAAGGTCCCACT GGATGTTCCCAACACCTCTCCTCGCCTCCCCTCTTTTACTGCATGTTCCTTCACATTGGG CCCCCCCAAAGTGCAAATTAGCTTGCG |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_152288 |
| Insert Size | 2400 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_152288.1, NP_689501.1 |
| RefSeq Size | 2239 bp |
| RefSeq ORF | 888 bp |
| Locus ID | 93129 |
| UniProt ID | Q9BRQ5 |
| Protein Families | Transmembrane |
| Gene Summary | Key regulator or component of store-operated Ca(2+) channel and transcription factor NFAT nuclear import.[UniProtKB/Swiss-Prot Function] |
Citations (5)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Antibody-mediated targeting of the orai1 calcium channel inhibits T cell function
,Cox, JH;Hussell, S;Søndergaard, H;Roepstorff, K;Bui, JV;Deer, JR;Zhang, J;Li, ZG;Lamberth, K;Kvist, PH;Padkjær, S;Haase, C;Zahn, S;Odegard, VH;,
PLoS ONE Dec 2013.
,PubMed ID 24376610
[ORAI3]
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Store-dependent and -independent Modes Regulating Ca2+ Release-activated Ca2+ Channel Activity of Human Orai1 and Orai3
,Shenyuan L. Zhang, J. Ashot Kozak, Weihua Jiang, Andriy V. Yeromin, Jing Chen, Ying Yu, Aubin Penna, Wei Shen, Victor Chi, and Michael D. Cahalan,
J. Biol. Chem., Jun 2008; 283: 17662 - 17671.
[ORAI3]
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Calcium inhibition and calcium potentiation of orai1, orai2 and orai3 calcium-release-activated calcium channels
,Wayne I Dehaven, Jeremy T Smyth, Rebecca R Boyles, and James W Putney Jr,
J Biol Chem. 2007 Jun 15;282(24):17548-56.
[ORAI3]
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Orai proteins interact with TRPC channels and confer responsiveness to store depletion
,Y Liao, C Erxleben, E Yildirim, J Abramowitz, DL Armstrong, and L Birnbaumer,
Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4682-7.
[ORAI3]
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Large Store-operated Calcium Selective Currents Due to Co-expression of Orai1 or Orai2 with the Intracellular Calcium Sensor, Stim1
,Jason C. Mercer, Wayne I. DeHaven, Jeremy T. Smyth, Barbara Wedel, Rebecca R. Boyles, Gary S. Bird, and James W. Putney, Jr,
J. Biol. Chem., 2006 Aug 25;281(34):24979-90.
[ORAI3]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202325 | ORAI3 (Myc-DDK-tagged)-Human ORAI calcium release-activated calcium modulator 3 (ORAI3) |
CNY 3,600.00 |
|
| RC202325L1 | Lenti ORF clone of Human ORAI calcium release-activated calcium modulator 3 (ORAI3), Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC202325L2 | Lenti ORF clone of Human ORAI calcium release-activated calcium modulator 3 (ORAI3), mGFP tagged |
CNY 6,000.00 |
|
| RC202325L3 | Lenti ORF clone of Human ORAI calcium release-activated calcium modulator 3 (ORAI3), Myc-DDK-tagged |
CNY 6,000.00 |
|
| RC202325L4 | Lenti ORF clone of Human ORAI calcium release-activated calcium modulator 3 (ORAI3), mGFP tagged |
CNY 6,000.00 |
|
| RG202325 | ORAI3 (tGFP-tagged) - Human ORAI calcium release-activated calcium modulator 3 (ORAI3) |
CNY 5,200.00 |
|
| SC324071 | ORAI3 (untagged)-Human ORAI calcium release-activated calcium modulator 3 (ORAI3) |
CNY 3,600.00 |
