GPSM2 (NM_013296) Human Untagged Clone
CAT#: SC111910
GPSM2 (untagged)-Human G-protein signaling modulator 2 (GPSM2)
CNY 4,968.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CMCS; DFNB82; LGN; PINS |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC111910 sequence for NM_013296 edited (data generated by NextGen Sequencing)
ATGGAGGAAAATTTGATAAGCATGAGAGAAGACCATTCTTTTCATGTTCGTTACAGAATG GAAGCTTCTTGCCTAGAGCTGGCCTTGGAAGGGGAACGTCTATGTAAATCAGGAGACTGC CGCGCTGGCGTGTCATTCTTTGAAGCTGCAGTTCAAGTTGGAACTGAAGACCTAAAAACA CTTAGCGCTATTTACAGCCAGTTGGGCAATGCTTATTTCTATTTGCATGATTATGCCAAA GCATTAGAATATCACCATCATGATTTAACCCTTGCAAGGACTATTGGAGACCAGCTGGGG GAAGCGAAAGCTAGTGGTAATCTGGGAAACACCTTAAAAGTTCTTGGGAATTTTGACGAA GCCATAGTTTGTTGTCAGCGACACCTAGATATTTCCAGAGAGCTTAATGACAAGGTGGGA GAAGCAAGAGCACTTTACAATCTTGGGAATGTGTATCATGCCAAAGGGAAAAGTTTTGGT TGCCCTGGTCCCCAGGATGTAGGAGAATTTCCAGAAGAAGTGAGAGATGCTCTGCAGGCA GCCGTGGATTTTTATGAGGAAAACCTATCATTAGTGACTGCTTTGGGTGACCGAGCGGCA CAAGGACGTGCCTTTGGAAATCTTGGAAACACACATTACCTCCTTGGCAACTTCAGGGAT GCAGTTATAGCTCATGAGCAGCGTCTCCTTATTGCAAAAGAATTTGGAGATAAAGCAGCT GAAAGAAGAGCATATAGCAACCTTGGAAATGCATATATATTTCTTGGTGAATTTGAAACT GCCTCGGAATACTACAAGAAGACACTACTGTTGGCCCGACAGCTTAAAGACCGAGCTGTA GAAGCACAGTCTTGTTACAGTCTTGGAAATACATATACTTTACTTCAAGACTATGAAAAG GCCATTGATTATCATCTGAAGCACTTAGCAATTGCTCAAGAGCTGAATGATAGAATTGGT GAAGGAAGAGCATGTTGGAGCTTAGGAAATGCATACACAGCACTAGGAAATCATGATCAA GCAATGCATTTTGCTGAAAAGCACTTGGAAATTTCAAGAGAGGTTGGGGATAAAAGTGGT GAACTAACAGCACGACTTAATCTCTCAGACCTTCAAATGGTTCTTGGTCTGAGCTACAGC ACAAATAACTCCATAATGTCTGAAAATACTGAAATTGATAGCAGTTTGAATGGTGTACGC CCCAAGTTGGGACGCCGGCATAGTATGGAAAATATGGAACTTATGAAGTTAACACCAGAA AAGGTACAGAACTGGAACAGTGAAATTCTTGCTAAGCAAAAACCTCTTATTGCCAAACCT TCTGCAAAGCTACTCTTTGTCAACAGACTGAAGGGGAAAAAATACAAAACGAATTCCTCC ACTAAAGTTCTCCAAGATGCCAGTAATTCTATTGACCACCGAATTCCAAATTCTCAGAGG AAAATCAGTGCAGATACTATTGGAGATGAAGGGTTCTTTGACTTATTAAGCCGATTTCAA AGCAATAGGATGGATGATCAGAGATGTTGCTTACAAGAAAAGAACTGCCATACAGCTTCA ACAACAACNNNTTCCACTCCCCCTAAAATGATGCTAAAAACATCATCTGTTCCTGTGGTA TCCCCCAACACGGATGAGTTTTTAGATCTTCTTGCCAGCTCACAGAGTCGCCGTCTGGAT GACCAGAGGGCTAGTTTCAGTAATTTGCCAGGGCTTCGTCTAACACAAAACAGCCAGTCG GTACTTAGCCACCTGATGACTAATGACAACAAAGAGGCTGATGAAGATTTCTTTGACATC CTTGTAAAATGTCAAGGATCCAGATTAGATGATCAAAGATGTGCTCCACCACCTGCTACC ACAAAGGGTCCGACAGTACCAGATGAAGACTTTTTCAGCCTTATTTTACGGTCCCAGGGA AAGAGAATGGATGAACAGAGAGTTCTTTTACAAAGAGATCAAAACAGAGACACTGACTTT GGGCTAAAGGACTTTTTGCAAAATAATGCTTTGTTGGAGTTTAAAAATTCAGGGAAAAAA TCGGCAGACCATTAG Clone variation with respect to NM_013296.4 1569 t=>n;1570 t=>n;1571 c=>n >OriGene 5' read for NM_013296 unedited
GGATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCGCGCCGGC CTCCTGCGGTGCCCCTGCCTTGGGGAGGGGCCGTGACCACCCGTCTGTCGCCCGAGGCGG CCGCCGCTGCACCTTCACCGCGTACCCGGGACCCGCCCGCCCGCGGGAGCTTATAATATG ACTCGATGGAGGAAAATTTGATAAGCATGAGAGAAGACCATTCTTTTCATGTTCGTTACA GAATGGAAGCTTCTTGCCTAGAGCTGGCCTTGGAAGGGGAACGTCTATGTAAATCAGGAG ACTGCCGCGCTGGCGTGTCATTCTTTGAAGCTGCAGTTCAAGTTGGAACTGAAGACCTAA AAACACTTAGCGCTATTTACAGCCAGTTGGGCAATGCTTATTTCTATTTGCATGATTATG CCAAAGCATTAGAATATCACCATCATGATTTAACCCTTGCAAGGACTATTGGAGACCAGC TGGGGGAAGCGAAAGCTAGTGGTAATCTGGGAAACACCTTAAAAGTTCTTGGGAATTTTG ACGAAGCCATAGTTTGTTGTCAGCGACACCTAGATATTTCCAGAGAGCTTAATGACAAGG TGGGAGAAGCAAGAGCACTTTACAATCTTGGGAATGTGTATCATGCCAAAGGGAAAAGTT TTGGTTGCCCTGGTCCCCAGGATGTAGGAGAATTTCCAGAAGAGTGAGAGATGCTCTGCA NGCAGCCGTGGATTTTTATGAGGAAAACCTATCATTAGTGACTGCTTTGGGTGACCGAGC GGCACAAGGACGTGCCTTTGGAAATCTTGNAACACACATTACCTNCTTGGNNCACTCAGG NATGCANGTATAGCTCATGAGCAGCGTCTCCTTATTGCAAAAGAATTTGGAGATNAAGCA GCTGAAAGAAGAGCATATAACACCCT >OriGene 3' read for NM_013296 unedited
GGGGGGGGGGGGGTTTAANNNGTTTTNTTNNNNNNNNNGNNNGTTGGCTATTTTTATCAC TTTTTTNCATTGNTNCAAGTACATTATTTTTACCAAACCAACATTGTTTCCCACTACATC CATGGTTATGTATAAAAAACCGCCATTGTCAATTAAGATGTTAAAAAATTATTTCCATAA GAGTATTAAATTCTAATCTATGATTCACTTAACTTCCTACTTTATAAACACTAGGTAAAG TAATCTCACAAGCTGCCAAAGAACACATCCCAAGCAGTAATCACAGACGATGAAGCACCT TACAGGACCCCTCCACCCTCAAACGCGCATGTCCAGAGAAGTATTAATGCCTTAATAGAC TACTGAAGGTTAACTATTTACATCATTCTAAAAATATTTTAAGCTGTATTACAGTGCTAT AAATTCTCCTTTTAAGGAAAAAAGTAATAGATTGTTTCCTTACCGTGTTTGAAAGGAAAA AAAATAAATCCATAGTAACTAATGGTCTGCCGATTTTTTCCCTGAATTTTTAAACTCCAA CAAAGCATTATTTTGCAAAAAGTCCTTTAGCCCAAAGTCAGTGTCTCTGTTTTGATCTCT TTGTAAAAGAACTCTCTGTTCATCCATTCTCTTTCCCTGGGACCGTAAAATAAGGCTGAA AAAGTCTTCATCTGGTACTGTCGGACCCTTTGTGGTAGCAGGTGGTGGAGCACATCTTTG ATCATCTAATCTGGATCCTTGACATTTTACAAGGATGTCAAAGAAATCTTCATCAGCCTC TTTGTTGTCATTAGTCATCAGGTGGCTAAGTACCGACTGGCTGTTTTGTGTTAGACGAAG CCCTGGCAAATTACTGAAACTAGCCCTCTGGTCATCCAGACGGCGACTCTGTGAGCTGGC AGAAGATCTAAAACTCATNCGTGTTGGGGGATACCACAG |
Restriction Sites | NotI-NotI |
ACCN | NM_013296 |
Insert Size | 3080 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_013296.3, NP_037428.2 |
RefSeq Size | 2806 bp |
RefSeq ORF | 2034 bp |
Locus ID | 29899 |
UniProt ID | P81274 |
Domains | TPR, GoLoco |
Protein Families | Druggable Genome |
Gene Summary | The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
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Other Versions
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RC205650L4 | Lenti ORF clone of Human G-protein signaling modulator 2 (GPSM2), mGFP tagged |
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RG205650 | GPSM2 (tGFP-tagged) - Human G-protein signaling modulator 2 (GPSM2) |
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SC318155 | GPSM2 (untagged)-Human G-protein signaling modulator 2 (GPSM2) |
CNY 7,220.00 |