United States
Germany
Japan
United Kingdom
China
DLL3 (NM_016941) Human Untagged Clone
CAT＃: SC111951
DLL3 (untagged)-Human delta-like 3 (Drosophila) (DLL3), transcript variant 1
CNY 4,608.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SCDO1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_016941 edited
GAATTCGGCACGAGGCCAGAAGGCCATGGTCTCCCCACGGATGTCCGGGCTCCTCTCCCA GACTGTGATCCTAGCGCTCATTTTCCTCCCCCAGACACGGCCCGCTGGCGTCTTCGAGCT GCAGATCCACTCTTTCGGGCCGGGTCCAGGCCCTGGGGCCCCGCGGTCCCCCTGCAGCGC CCGGCTCCCCTGCCGCCTCTTCTTCAGAGTCTGCCTGAAGCCTGGGCTCTCAGAGGAGGC CGCCGAGTCCCCGTGCGCCCTGGGCGCGGCGCTGAGTGCGCGCGGACCGGTCTACACCGA GCAGCCCGGAGCGCCCGCGCCTGATCTCCCACTGCCCGACGGCCTCTTGCAGGTGCCCTT CCGGGACGCCTGGCCTGGCACCTTCTCTTTCATCATCGAAACCTGGAGAGAGGAGTTAGG AGACCAGATTGGAGGGCCCGCCTGGAGCCTGCTGGCGCGCGTGGCTGGCAGGCGGCGCTT GGCAGCCGGAGGCCCGTGGGCCCGGGACATTCAGCGCGCAGGCGCCTGGGAGCTGCGCTT CTCGTACCGCGCGCGCTGCGAGCCGCCTGCCGTCGGGACCGCGTGCACGCGCCTCTGCCG TCCGCGCAGCGCCCCCTCGCGGTGCGGTCCGGGACTGCGCCCCTGCGCACCGCTCGAGGA CGAATGTGAGGCGCCGCCGGTGTGCCGAGCAGGCTGCAGCCCTGAGCATGGCTTCTGTGA ACAGCCCGGTGAATGCCGATGCCTAGAGGGCTGGACTGGACCCCTCTGCACGGTCCCTGT CTCCACCAGCAGCTGCCTCAGCCCCAGGGGCCCGTCCTCTGCTACCACCGGATGCCTTGT CCCTGGGCCTGGGCCCTGTGACGGGAACCCGTGTGCCAATGGAGGCAGCTGTAGTGAGAC ACCCAGGTCCTTTGAATGCACCTGCCCGCGTGGGTTCTACGGGCTGCGGTGTGAGGTGAG CGGGGTGACATGTGCAGATGGACCCTGCTTCAACGGCGGCTTGTGTGTCGGGGGTGCAGA CCCTGACTCTGCCTACATCTGCCACTGCCCACCCGGTTTCCAAGGCTCCAACTGTGAGAA GAGGGTGGACCGGTGCAGCCTGCAGCCATGCCGCAATGGCGGACTCTGCCTGGACCTGGG CCACGCCCTGCGCTGCCGCTGCCGCGCCGGCTTCGCGGGTCCTCGCTGCGAGCACGACCT GGACGACTGCGCGGGCCGCGCCTGCGCTAACGGCGGCACGTGTGTGGAGGGCGGCGGCGC GCACCGCTGCTCCTGCGCGCTGGGCTTCGGCGGCCGCGACTGCCGCGAGCGCGCGGACCC GTGCGCCGCGCGCCCCTGTGCTCACGGCGGCCGCTGCTACGCCCACTTCTCCGGCCTCGT CTGCGCTTGCGCTCCCGGCTACATGGGAGCGCGGTGTGAGTTCCCAGTGCACCCCGACGG CGCAAGCGCCTTGCCCGCGGCCCCGCCGGGCCTCAGGCCCGGGGACCCTCAGCGCTACCT TTTGCCTCCGGCTCTGGGACTGCTCGTGGCCGCGGGCGTGGCCGGCGCTGCGCTCTTGCT GGTCCACGTGCGCCGCCGTGGCCACTCCCAGGATGCTGGGTCTCGCTTGCTGGCTGGGAC CCCGGAGCCGTCAGTCCACGCACTCCCGGATGCACTCAACAACCTAAGGACGCAGGAGGG TTCCGGGGATGGTCCGAGCTCGTCCGTAGATTGGAATCGCCCTGAAGATGTAGACCCTCA AGGGATTTATGTCATATCTGCTCCTTCCATCTACGCTCGGGAGGTAGCGACGCCCCTTTT CCCCCCGCTACACACTGGGCGCGCTGGGCAGAGGCAGCACCTGCTTTTTCCCTACCCTTC CTCGATTCTGTCCGTGAAATGAATTGGGTAGAGTCTCTGGAAGGTTTTAAGCCCATTTTC AGTTCTAACTTACTTTCATCCTATTTTGCATCCCTCTTATCGTTTTGAGCTACCTGCCAT CTTCTCTTTGAAAAACCTATGGGCTTGAGGAGGTCACGATGCCGACTCCGCCAGAGCTTT TCCACTGATTGTACTCAGCGGGGAGGCAGGGGAGGCAGAGGGGCAGCCTCTCTAATGCTT CCTACTCATTTTGTTTCTAGGCCTGACGCGTCTCCTCCATCCGCACCTGGAGTCAGAGCG TGGATTTTTGTATTTGCTCGGTGGTGCCCAGTCTCTGCCCCAGAGGCTTTGGAGTTCAAT CTTGAAGGGGTGTCTGGGGGAACTTTACTGTTGCAAGTTGTAAATAATGGTTATTTATAT CCTATTTTTTCTCACCCCATCTCTCTAGAAACACCTATAAAGGCTATTATTGTGATCAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_016941 unedited
CAAAATTTGTATACGACTACTATAGGGCGGCCGCGAATTCGGCACGAGCCANAAGCCATG GTCTCCCCACGGATGTCCGGGCTCCTCTCCCAGACTGTGATCCTAGCGCTCATTTTCCTC CCCCAGACACGGCCCGCTGGCGTCTTCGAGCTGCAGATCCACTCTTTCGGGCCGGGTCCA GGCCCTGGGGCCCCGCGGTCCCCCTGCAGCGCCCGGCTCCCCTGCCGCCTCTTCTTCAGA GTCTGCCTGAAGCCTGGGCTCTCAGAGGAGGCCGCCGAGTCCCCGTGCGCCCTGGGCGCG GCGCTGAGTGCGCGCGGACCGGTCTACACCGAGCAGCCCGGAGCGCCCGCGCCTGATCTC CCACTGCCCGACGGCCTCTTGCAGGTGCCCTTCCGGGACGCCTGGCCTGGCACCTTCTCT TTCATCATCGAAACCTGGAGAGAGGAGTTAGGAGACCAGATTGGAGGGCCCGCCTGGAGC CTGCTGGCGCGCGTGGCTGGCAGGCGGCGCTTGGCAGCCGGAGGCCCGTGGGCCCGGGAC ATTCAGCGCGCAGGCGCCTGGGAGCTGCGCTTCTCGTACCGCGCGCGCTGCGAGCCGCCT GCCGTCGGGACCGCGTGCACGCGCCTCTGCCGTCCGCGCAGCGCCCCCTCGCGGTGCGGT CCGGGACTGCGCCCCTGCGCNACCGCTCGAGACGAATGTGAGGCGCCGCCGGTGTGCCGN AGCAGCTGCAGCCCTGAGCATGGCTTCTGTGAACAGCCCCGGGGATGCCCGATGCCTANA GGGGCTGACTGGACCCCTCTGGACGGNTCCTGGTTCCCCAGCAGTTGCCTCAGCCCCAGG GCCCGTCCTTTGCTACCACCGGAGCCTTGTCCTGGGCCTTGGCCCTGGAACGGAACCCCG GTGCCATGGAGGCANCTGTATGGAGACACCCAGTCTTTGTATGCACTGCC >OriGene 3' read for NM_016941 unedited
AAGGTGAGGGGGNCCAAACCAGGNGTGGTCGGCGGGTAGGGCGTGTAGCAAAAATAGGGA GTAAATAACCATTAGGTACAACTTGCAGCAGGGAAGTTCGGCCAGACACCCCGTCAAGAT TGAACTCCAAAGCCTCTGGGGCAGAGACTGGGCACCACCGAGCAAATACAAAAATCCACG CTCTGACTCCAGGTGCGGATGGAGGAGACGCGTCAGGCCTAGAAACAAAATGAGTAGGAA GCATTAGAGAGGCTGCCCCTCTGCCTCCCCTGCCTCCCCGCTGAGTACAATCAGTGGAAA AGCTCTGGCGGAGTCGGCATCGTGACCTCCTCAAGCCCATAGGTTTTTCAAAGAGAAGAT GGCAGGTAGCTCAAAACGATAAGAGGGATGCAAACTAGGATGAAAGTTACCTATAACTGA GAATGGGCTTAAGACCTTCCAGAGACTCTACCCAATTCATTTCACGGACAGAACCGTCGA AGGGTCCGGAAACAGCAGGTGCTGCCTTCTGCCATCGCGCCCAGAGTGTATCGCTGGGAA AAGGCGCCGCTCCCCCTGCCCGAGCGTAGCTGGTAGGAGCCGACTTGACATAAATCCCTT GAGGGCCTACATACTGCGGGGTGATTCCAGTCTACGGCACACCCTGGACCCTTCCCGGAA CCCTCCGGTGTCCTTAGGCTGGTGGGCGCATCCCGCAGGGCGTGGAATGATTGTCTCCCG GGCCCCCCCCCGCTTTGCCATTCCCCCATCCCTCGGCCTGGCTCACCGGCGGGCCCCGTT GCACCCGCCAGGAGTGCCACTGCCTGTCTCACCCCCGGTCGTCCCCTATGCTCTTTCCTC CTTCTGTGGGCTTTAAGCGGGGATCGTCCGTGCGCGCCCGGACTCACGACGCTCCGTCGA TGCCCCCGGCCTCCACGAAGCCTCTGTTCCGCTCGTCGCGCCCACGGGCGTCCTTCTACA GCGCGTTCCCTACGACACCAATAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_016941 |
| Insert Size | 2370 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016941.2, NP_058637.1 |
| RefSeq Size | 2359 bp |
| RefSeq ORF | 1857 bp |
| Locus ID | 10683 |
| UniProt ID | Q9NYJ7 |
| Domains | EGF_CA, EGF, EGF |
| Protein Families | Cancer stem cells, Druggable Genome, ES Cell Differentiation/IPS, Stem cell relevant signaling - DSL/Notch pathway, Transmembrane |
| Protein Pathways | Notch signaling pathway |
| Gene Summary | This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo
,Saunders, LR;Bankovich, AJ;Anderson, WC;Aujay, MA;Bheddah, S;Black, K;Desai, R;Escarpe, PA;Hampl, J;Laysang, A;Liu, D;Lopez-Molina, J;Milton, M;Park, A;Pysz, MA;Shao, H;Slingerland, B;Torgov, M;Williams, SA;Foord, O;Howard, P;Jassem, J;Badzio, A;Czapiewski, P;Harpole, DH;Dowlati, A;Massion, PP;Travis, WD;Pietanza, MC;Poirier, JT;Rudin, CM;Stull, RA;Dylla, SJ;,
Sci Transl Med
,PubMed ID 26311731
[DLL3]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200005 | DLL3 (Myc-DDK-tagged)-Human delta-like 3 (Drosophila) (DLL3), transcript variant 1 |
CNY 6,904.00 |
|
| RC200005L1 | Lenti-ORF clone of DLL3 (Myc-DDK-tagged)-Human delta-like 3 (Drosophila) (DLL3), transcript variant 1 |
CNY 9,304.00 |
|
| RC200005L2 | Lenti-ORF clone of DLL3 (mGFP-tagged)-Human delta-like 3 (Drosophila) (DLL3), transcript variant 1 |
CNY 9,304.00 |
|
| RC200005L3 | Lenti-ORF clone of DLL3 (Myc-DDK-tagged)-Human delta-like 3 (Drosophila) (DLL3), transcript variant 1 |
CNY 9,304.00 |
|
| RC200005L4 | Lenti-ORF clone of DLL3 (mGFP-tagged)-Human delta-like 3 (Drosophila) (DLL3), transcript variant 1 |
CNY 9,304.00 |
|
| RG200005 | DLL3 (tGFP-tagged) - Human delta-like 3 (Drosophila) (DLL3), transcript variant 1 |
CNY 8,504.00 |
