EHMT1/GLP (EHMT1) (NM_024757) Human Untagged Clone
CAT#: SC112042
EHMT1 (untagged)-Human euchromatic histone-lysine N-methyltransferase 1 (EHMT1), transcript variant 1
CNY 25,080.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | EHMT1-IT1; Eu-HMTase1; EUHMTASE1; FP13812; GLP; GLP1; KLEFS1; KMT1D |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_024757, the custom clone sequence may differ by one or more nucleotides
ATGGCCGCCGCCGATGCCGAGGCAGTTCCGGCGAGGGGGGAGCCTCAGCAGGATTGCTGTGTGAAAACCG AGCTGCTGGGAGAAGAGACACCTATGGCTGCCGATGAAGGCTCAGCAGAGAAACAGGCAGGAGAGGCCCA CATGGCTGCGGACGGTGAGACCAATGGGTCTTGTGAAAACAGCGATGCCAGCAGTCATGCAAATGCTGCA AAGCACACTCAGGACAGCGCAAGGGTCAACCCCCAGGATGGCACCAACACACTAACTCGGATAGCGGAAA ATGGGGTTTCAGAAAGAGACTCAGAAGCGGCGAAGCAAAACCACGTCACTGCCGACGACTTTGTGCAGAC TTCTGTCATCGGCAGCAACGGATACATCTTAAATAAGCCGGCCCTACAGGCACAGCCCTTGAGGACTACC AGCACTCTGGCCTCTTCGCTGCCTGGCCATGCTGCAAAAACCCTTCCTGGAGGGGCTGGCAAAGGCAGGA CTCCAAGCGCTTTTCCCCAGACGCCAGCCGCCCCACCAGCCACCCTTGGGGAGGGGAGTGCTGACACAGA GGACAGGAAGCTCCCGGCCCCTGGCGCCGACGTCAAGGTCCACAGGGCACGCAAGACCATGCCGAAGTCC GTCGTGGGCCTGCATGCAGCCAGTAAAGATCCCAGAGAAGTTCGAGAAGCTAGAGATCATAAGGAACCAA AAGAGGAGATCAACAAAAACATTTCTGACTTTGGACGACAGCAGCTTTTACCCCCCTTCCCATCCCTTCA TCAGTCGCTACCTCAGAACCAGTGCTACATGGCCACCACAAAATCACAGACAGCTTGCTTGCCTTTTGTT TTAGCAGCTGCAGTATCTCGGAAGAAAAAACGAAGAATGGGAACCTATAGCCTGGTTCCTAAGAAAAAGA CCAAAGTATTAAAACAGAGGACGGTGATTGAGATGTTTAAGAGCATAACTCATTCCACTGTGGGTTCCAA GGGGGAGAAGGACCTGGGCGCCAGCAGCCTGCACGTGAATGGGGAGAGCCTGGAGATGGACTCGGATGAG GACGACTCAGAGGAGCTCGAGGAGGACGACGGCCATGGTGCAGAGCAGGCGGCCGCGTTCCCCACAGAGG ACAGCAGGACTTCCAAGGAGAGCATGTCGGAGGCTGATCGCGCCCAGAAGATGGACGGGGAGTCCGAGGA GGAGCAGGAGTCCGTGGACACCGGGGAGGAGGAGGAAGGCGGTGACGAGTCTGACCTGAGTTCGGAATCC AGCATTAAGAAGAAATTTCTCAAGAGGAAAGGAAAGACCGACAGTCCCTGGATCAAGCCAGCCAGGAAAA GGAGGCGGAGAAGTAGAAAGAAGCCCAGCGGTGCCCTCGGTTCTGAGTCGTATAAGTCATCTGCAGGAAG CGCTGAGCAGACGGCACCAGGAGACAGCACAGGGTACATGGAAGTTTCTCTGGACTCCCTGGATCTCCGA GTCAAAGGAATTCTGTCTTCACAAGCAGAAGGGTTGGCCAACGGTCCAGATGTGCTGGAGACAGACGGCC TCCAGGAAGTGCCTCTCTGCAGCTGCCGGATGGAAACACCGAAGAGTCGAGAGATCACCACACTGGCCAA CAACCAGTGCATGGCTACAGAGAGCGTGGACCATGAATTGGGCCGGTGCACAAACAGCGTGGTCAAGTAT GAGCTGATGCGCCCCTCCAACAAGGCCCCGCTCCTCGTGCTGTGTGAAGACCACCGGGGCCGCATGGTGA AGCACCAGTGCTGTCCTGGCTGTGGCTACTTCTGCACAGCGGGTAATTTTATGGAGTGTCAGCCCGAGAG CAGCATCTCTCACCGTTTCCACAAAGACTGTGCCTCTCGAGTCAATAACGCCAGCTATTGTCCCCACTGT GGGGAGGAGAGCTCCAAGGCCAAAGAGGTGACGATAGCTAAAGCAGACACCACCTCGACCGTGACACCAG TCCCCGGGCAGGAGAAGGGCTCGGCCCTGGAGGGCAGGGCCGACACCACAACGGGCAGTGCTGCCGGGCC ACCACTCTCGGAGGACGACAAGCTGCAGGGTGCAGCCTCCCACGTGCCCGAGGGCTTTGATCCAACGGGA CCTGCTGGGCTTGGGAGGCCAACTCCCGGCCTTTCCCAGGGACCAGGGAAGGAAACCTTGGAGAGCGCTC TCATCGCCCTCGACTCGGAAAAACCCAAGAAGCTTCGCTTCCACCCAAAGCAGCTGTACTTCTCCGCCAG GCAAGGGGAGCTTCAGAAGGTGCTCCTCATGCTGGTGGACGGAATTGACCCCAACTTCAAAATGGAGCAC CAGAATAAGCGCTCTCCACTGCACGCCGCGGCAGAGGCTGGACACGTGGACATCTGCCACATGCTGGTTC AGGCGGGCGCTAATATTGACACCTGCTCAGAAGACCAGAGGACCCCGTTGATGGAAGCAGCCGAAAACAA CCATCTGGAAGCAGTGAAGTACCTCATCAAGGCTGGGGCCCTGGTGGATCCCAAGGACGCAGAGGGCTCT ACGTGTTTGCACCTGGCTGCCAAGAAAGGCCACTACGAAGTGGTCCAGTACCTGCTTTCAAATGGACAGA TGGACGTCAACTGTCAGGATGACGGAGGCTGGACACCCATGATCTGGGCCACAGAGTACAAGCACGTGGA CCTCGTGAAGCTGCTGCTGTCCAAGGGCTCTGACATCAACATCCGAGACAACGAGGAGAACATTTGCCTG CACTGGGCGGCGTTCTCCGGCTGCGTGGACATAGCCGAGATCCTGCTGGCTGCCAAGTGCGACCTCCACG CCGTGAACATCCACGGAGACTCGCCACTGCACATTGCCGCCCGGGAGAACCGCTACGACTGTGTCGTCCT CTTTCTTTCTCGGGATTCAGATGTCACCTTAAAGAACAAGGAAGGAGAGACGCCCCTGCAGTGTGCGAGC CTCAACTCTCAGGTGTGGAGCGCTCTGCAGATGAGCAAGGCTCTGCAGGACTCGGCCCCCGACAGGCCCA GCCCCGTGGAGAGGATAGTGAGCAGGGACATCGCTCGAGGCTACGAGCGCATCCCCATCCCCTGTGTCAA CGCCGTGGACAGCGAGCCATGCCCCAGCAACTACAAGTACGTCTCTCAGAACTGCGTGACGTCCCCCATG AACATCGACAGAAATATCACTCATCTGCAGTACTGCGTGTGCATCGACGACTGCTCCTCCAGCAACTGCA TGTGCGGCCAGCTCAGCATGCGCTGCTGGTACGACAAGGATGGCCGGCTCCTGCCAGAGTTCAACATGGC GGAGCCTCCCTTGATCTTCGAATGCAACCACGCGTGCTCCTGCTGGAGGAACTGCCGAAATCGCGTCGTA CAGAATGGTCTCAGGGCAAGGCTGCAGCTCTACCGGACGCGGGACATGGGCTGGGGCGTGCGGTCCCTGC AGGACATCCCACCAGGCACCTTTGTCTGCGAGTATGTTGGGGAGCTGATTTCAGACTCAGAAGCCGACGT TCGAGAGGAAGATTCTTACCTCTTTGATCTCGACAATAAGGACGGGGAGGTTTACTGCATCGACGCGCGG TTCTACGGGAACGTCAGCCGGTTCATCAACCACCACTGCGAGCCCAACCTGGTGCCCGTGCGCGTGTTCA TGGCCCACCAGGACCTGCGGTTCCCCCGGATCGCCTTCTTCAGCACCCGCCTGATCGAGGCCGGCGAGCA GCTCGGGTTTGACTATGGAGAGCGCTTCTGGGACATCAAAGGCAAGCTCTTCAGCTGCCGCTGCGGCTCC CCCAAGTGCCGGCACTCGAGCGCGGCCCTGGCCCAGCGTCAGGCCAGCGCGGCCCAGGAGGCCCAGGAGG ACGGCTTGCCCGACACCAGCTCCGCGGCTGCCGCCGACCCCCTATGA |
Restriction Sites | NotI-NotI |
ACCN | NM_024757 |
Insert Size | 5250 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_024757.3, NP_079033.3 |
RefSeq Size | 5123 bp |
RefSeq ORF | 3804 bp |
Locus ID | 79813 |
UniProt ID | Q9H9B1 |
Domains | SET, ANK, PreSET, Pre-SET |
Protein Families | Druggable Genome |
Protein Pathways | Lysine degradation |
Gene Summary | The protein encoded by this gene is a histone methyltransferase that methylates the lysine-9 position of histone H3. This action marks the genomic region packaged with these methylated histones for transcriptional repression. This protein may be involved in the silencing of MYC- and E2F-responsive genes and therefore could play a role in the G0/G1 cell cycle transition. Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome, also known as Kleefstra syndrome). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC214949 | EHMT1 (Myc-DDK-tagged)-Human euchromatic histone-lysine N-methyltransferase 1 (EHMT1), transcript variant 1 |
CNY 12,920.00 |
|
RC214949L3 | Lenti-ORF clone of EHMT1 (Myc-DDK-tagged)-Human euchromatic histone-lysine N-methyltransferase 1 (EHMT1), transcript variant 1 |
CNY 14,820.00 |
|
RC214949L4 | Lenti-ORF clone of EHMT1 (mGFP-tagged)-Human euchromatic histone-lysine N-methyltransferase 1 (EHMT1), transcript variant 1 |
CNY 14,820.00 |
|
RG214949 | EHMT1 (tGFP-tagged) - Human euchromatic histone-lysine N-methyltransferase 1 (EHMT1), transcript variant 1 |
CNY 15,152.00 |
|
SC328062 | EHMT1 (untagged)-Human euchromatic histone-lysine N-methyltransferase 1 (EHMT1) transcript variant 1 |
CNY 9,952.00 |
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