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Epoxide hydrolase (EPHX1) (NM_000120) Human Untagged Clone
CAT＃: SC112331
EPHX1 (untagged)-Human epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1), transcript variant 1
CNY 5,488.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EPHX; EPOX; HYL1; MEH |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112331 sequence for NM_000120 edited (data generated by NextGen Sequencing)
ATGTGGCTAGAAATCCTCCTCACTTCAGTGCTGGGCTTTGCCATCTACTGGTTCATCTCC CGGGACAAAGAGGAAACTTTGCCACTTGAAGATGGGTGGTGGGGGCCAGGCACGAGGTCC GCAGCCAGGGAGGACGACAGCATCCGCCCTTTCAAGGTGGAAACGTCAGATGAGGAGATC CACGACTTACACCAGAGGATCGATAAGTTCCGTTTCACCCCACCTTTGGAGGACAGCTGC TTCCACTATGGCTTCAACTCCAACTACCTGAAGAAAGTCATCTCCTACTGGCGGAATGAA TTTGACTGGAAGAAGCAGGTGGAGATTCTCAACAGATACCCTCACTTCAAGACTAAAATT GAAGGGCTGGACATCCACTTCATCCACGTGAAGCCCCCCCAGCTGCCCGCAGGCCATACC CCGAAGCCCTTGCTGATGGTGCACGGCTGGCCCGGCTCTTTCTACGAGTTTTATAAGATC ATCCCACTCCTGACTGACCCCAAGAACCATGGCCTGAGCGATGAGCACGTTTTTGAAGTC ATCTGCCCTTCCATCCCTGGCTATGGCTTCTCAGAGGCATCCTCCAAGAAGGGGTTCAAC TCGGTGGCCACCGCCAGGATCTTTTACAAGCTGATGCTGCGGCTGGGCTTCCAGGAATTC TACATTCAAGGAGGGGACTGGGGGTCCCTGATCTGCACTAATATGGCCCAGCTGGTGCCC AGCCACGTGAAAGGCCTGCACTTGAACATGGCTTTGGTTTTAAGCAACTTCTCTACCCTG ACCCTCCTCCTGGGACAGCGTTTCGGGAGGTTTCTTGGCCTCACTGAGAGGGATGTGGAG CTGCTGTACCCCGTCAAGGAGAAGGTATTCTACAGCCTGATGAGGGAGAGCGGCTACATG CACATCCAGTGCACCAAGCCTGACACCGTAGGCTCTGCTCTGAATGACTCTCCTGTGGGT CTGGCTGCCTATATTCTAGAGAAGTTTTCTACCTGGACCAATACGGAATTCCGATACCTG GAGGATGGAGGCCTGGAAAGGAAGTTCTCCCTGGACGACCTGCTGACCAACGTCATGCTC TACTGGACAACAGGCACCATCATCTCCTCCCAGCGCTTCTACAAGGAGAACCTGGGACAG GGCTGGATGACCCAGAAGCATGAGCGGATGAAGGTCTATGTGCCCACTGGCTTCTCTGCC TTCCCTTTTGAGCTATTGCACACGCCTGAAAAGTGGGTGAGGTTCAAGTACCCAAAGCTC ATCTCCTATTCCTACATGGTTCGTGGGGGCCACTTTGCGGCCTTTGAGGAGCCGGAGCTG CTCGCCCAGGACATCCGCAAGTTCCTGTCGGTGCTGGAGCGGCAATGA Clone variation with respect to NM_000120.3 357 g=>a;990 c=>t >OriGene 5' read for NM_000120 unedited
GTTCAAATTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACCAGGCAGAGCTCCC AGCTCTCTTTCCCAAGGAGTAATCAGAGGGTGAGAACGTGGAGCCTGGTGGACAGGTGAA AGCACTGGGATCTTTCTGCCCAGAAAGGGGAAAGTTGCACATTTATATCCTAGAGGGAAG CGACAGCAGTGCTTCTCCCTGTGCTGAGGAGCCATGTGGCTAGAAATCCTCCTCACTTCA GTGCTGGGCTTTGCCATCTACTGGTTCATCTCCCGGGACAAAGAGGAAACTTTGCCACTT GAAGATGGGTGGTGGGGGCCAGGCACGAGGTCCGCAGCCAGGGAGGACGACAGCATCCGC CCTTTCAAGGTGGAAACGTCAGATGAGGAGATCCACGACTTACACCAGAGGATCGATAAG TTCCGTTTCACCCCACCTTTGGAGGACAGCTGCTTCCACTATGGCTTCAACTCCAACTAC CTGAAGAAAGTCATCTCCTACTGGCGGAATGAATTTGACTGGAAGAAGCAGGTGGAGATT CTCAACAGATACCCTCACTTCAAGACTAAAATTGAAGGGCTGGACATCCACTTCATCCAC GTGAAGCCCCCCCAGCTGCCCGCAGGCCATACCCCGAAGCCCTTGCTGATGGTGCACGGC TGGCCCGGCTCTTTCTACGAGTTTTATAAGATCATCCCACTCCTGACTGACCCCAAGAAC CATGGCCTGAGCGATGAGCACGTTTTTGAAGTCATCTGCCCTTCCATCCCTGGCTATGGC TTCTCAGAGGCATCCTCCAGAAGGNGTTCAACTCGGTGGCCACGCCAGGATCTTTTAAAG CTGATGCTGNCGCTGNGCTTCCAGGAATTCTACATTCAGGGGAGGGACTGGGGTCCCTGA TCTGCACTATATGGCCCNAGCTGTGCCCANCN >OriGene 3' read for NM_000120 unedited
NTTCTTGNACCCGGCCGCATTCTANGATCGAGTTTTTTTTTTTTTTTTTTTAGAGTAAAG TCGTTTATCATCAAAGCCATGTTGCTTACCACACGGAGTTGGGGGTTGGGGAGTGAGCTT GGAGGGGTGAGGGGGTGAGCGTGGGCTCCCAGCATGGGCAGGGGACGGAGGCAAACTCAT TCCTCAGAAAAGGGGTATCTTCCCCAAGAAAAGCCTGGAGGGCACTTGTGGGGGGAGGTG GCAGGCGGGGGGAGAGGGGTGGGTCATTGCCGCTCCAGCACCGACAGGAACTTGCGGATG TCCTGGGCGAGCAGCTCCGGCTCCTCAAAGGCCGCAAAGTGGCCCCCACGAACCATGTAG GAATAGGAGATGAGCTTTGGGTACTTGAACCTCACCCACTTTTCAGGCGTGTGCAATAGC TCAAAAGGGAAGGCAGAGAAGCCAGTGGGCACATAGACCTTCATCCGCTCATGCTTCTGG GTCATCCAGCCCTGTCCCAGGTTCTCCTTGTAAAAGCGCTGGGAGGAGATGATGGTGCCT GTTGTCCAGTAGAGCATGACGTTGGTCAGCAGGTCGTCCAGGGAGAACTTCCTTTCCAGG CCCTCATCCTTCAGGTATCGGAATTCCGTATTGGTCCAGGTAGAAAACTTCTCTAGAATA TAGGCAGCCGGACCCACAGAGAGTCATTCAGAGCAGAACCTACCGTGTCAGGCTTGGTGC ACTGGATGTGCATGTAACCGCTTTTCCTTATAAGGCTGTAAAATACCTCTTCTTTGACGG GTACAGAAGTTCCCATTCCTTTTAATGAGGCCAAGAACCTTCCGAAACCCTGTCCCAGGA GAAGGGTCAGGGTAAAAAATTTTGTTAAAACCAAAGCCTGTTCAGGGCCGGCCCTTACGG GGTTGGGCCCACATGGGCCTATTATGGAATACAGGACCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_000120 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000120.2, NP_000111.1 |
| RefSeq Size | 1856 bp |
| RefSeq ORF | 1368 bp |
| Locus ID | 2052 |
| UniProt ID | P07099 |
| Domains | abhydrolase |
| Protein Families | Druggable Genome, Protease |
| Protein Pathways | Metabolism of xenobiotics by cytochrome P450 |
| Gene Summary | Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2008] Transcript Variant: This variant (1) is the longer transcript. Variants 1, 2 and 3 encode the same protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A Novel Activity of Microsomal Epoxide Hydrolase: Metabolism of the Endocannabinoid 2-Arachidonoylglycerol
,Nithipatikom, K;Endsley, MP;Pfeiffer, AW;Falck, JR;Campbell, WB;,
J. Lipid Res.
,PubMed ID 24958911
[EPHX1]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200621 | EPHX1 (Myc-DDK-tagged)-Human epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1), transcript variant 1 |
CNY 5,488.00 |
|
| RC200621L1 | Lenti ORF clone of Human epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC200621L2 | Lenti ORF clone of Human epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC200621L3 | Lenti ORF clone of Human epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200621L4 | Lenti ORF clone of Human epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RG200621 | EPHX1 (tGFP-tagged) - Human epoxide hydrolase 1, microsomal (xenobiotic) (EPHX1), transcript variant 1 |
CNY 7,088.00 |
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