Apoptosis enhancing nuclease (AEN) (NM_022767) Human Untagged Clone
CAT#: SC112416
AEN (untagged)-Human apoptosis enhancing nuclease (AEN)
CNY 2,400.00
CNY 6,270.00
Product images
CNY 6,281.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | ISG20L1; pp12744 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_022767, the custom clone sequence may differ by one or more nucleotides
ATGGTACCCCGGGAGGCCCCTGAGTCTGCTCAGTGCCTGTGCCCTTCCCTCACCATCCCAAATGCCAAGG ATGTGCTTCGGAAGAGGCACAAGAGAAGGAGCCGACAGCACCAGCGGTTCATGGCCCGGAAGGCCTTGCT GCAGGAGCAGGGGCTGCTGAGCATGCCTCCAGAACCAGGGTCCTCCCCACTGCCCACCCCTTTCGGGGCA GCGACAGCAACTGAAGCTGCCAGCAGTGGGAAGCAGTGTCTGAGGGCTGGATCTGGCAGTGCCCCATGCA GCAGAAGGCCTGCTCCCGGGAAAGCCTCAGGGCCCTTGCCCAGCAAGTGTGTGGCTATCGACTGTGAGAT GGTGGGCACGGGACCCCGAGGGCGGGTAAGCGAGCTGGCCCGCTGTTCCATTGTGAGCTACCATGGCAAT GTCCTCTATGACAAGTACATCAGGCCTGAGATGCCCATCGCTGACTACCGTACCCGCTGGAGTGGCATCA CTCGGCAGCACATGCGCAAGGCTGTCCCCTTCCAGGTGGCCCAGAAAGAGATCCTTAAGCTCCTGAAGGG CAAGGTGGTGGTGGGGCACGCGCTGCACAACGACTTCCAGGCGCTCAAGTATGTCCACCCTCGGAGCCAG ACCCGGGATACGACCTATGTCCCAAACTTCCTCAGCGAGCCCGGCCTCCACACCCGGGCCCGGGTCTCTC TAAAGGACCTGGCCCTGCAGCTGCTGCACAAGAAGATCCAGGTGGGCCAGCACGGGCACTCATCAGTAGA AGATGCCACGACAGCCATGGAGCTCTACCGGCTGGTGGAGGTGCAGTGGGAACAGCAGGAGGCCCGCAGC CTCTGGACCTGCCCCGAGGACAGAGAACCTGACAGCAGCACAGACATGGAACAGTACATGGAGGACCAGT ACTGGCCCGATGACCTGGCCCACGGCAGCAGAGGAGGAGCCAGGGAGGCACAGGACAGAAGGAATTGA >OriGene 5' read for NM_022767 unedited
NGGGGGTGTTCAGNAATTTATGTNAATACGAACTNCACTTTTAGGGNNNCGGCCGCGNNA ATTCGGCACGNAGGGATNNCTGGCNNAGTGCCCCATGNNCAGCAGNAAGGGCCTGGCTCC CGGGNAAAGCCTCAGGGCCCTTGCCCAGCAAGTGTGTGGCTATCGACTGTGAGATGGTGG GCACGGGACCCCGAGGGCGGGTAAGCGAGCTGGCCCGCTGTTCCATTGTGAGCTACCATG GCGATGTCCTCTATGACAAGTACATCAGGCCTGAGATGCCCATCGCTGACTACCGTACCC GCTGGAGTGGCATCACTCGGCAGCACATGCGCAAGGCTGTCCCCTTCCAGGTGGCCCAGA AAGAGATCCTTAAGCTCCTGAAGGGCAAGGTGGTGGTGGGGCACGCGCTGCACAACGACT TCCAGGCGCTCAAGTATGTCCACCCTCGGAGCCAGACCCGGGATACCACCTATGTCCCAA ACTTCCTCAGCGAGCCCGGCCTCCACACCCGGGCCCGGGTCTCTCTAAAGGACCTGGCCC TGCAGCTGCTGCACAAGAAGATCCAGGTGGGCCAGCACGGGCACTCATCAGTAGAAGATG CCACGACAGCCATGGAGCTCTACCGGCTGGTGGAGGTGCAGTGGGAACAGCAGGAGGCCC GCAGCCTCTGNGACCTGCCCCGAGACAGAGAACCTGACAGCAGCACAGACATGGAACAGT ACATGGAGGACCAGTACTGGCCCGATGACCTGGCCCACGGCAGCAGAGGAGGAGCCAGGG AGGCACAGGACAGAAAGAATTGAGAAAGGGGCGGGGCTCCCTGGCTGGGCTTNCNGTGTG GCCGGTAAGAAGTGGGGGCCAGAGAGCAGCGGGCACTCCTTCCTGGGCAGGNTGGNGCAN GATGCANTGAGCCCGCCCCAGGCCAGNAGAGTTGGGGTCATCTGTTACCTTGC >OriGene 3' read for NM_022767 unedited
TTGTACCGCGGCCGCTTCTAAATCGAGTTTTTTTTTTTTTTTTTTCACGTTTCCAATTGA GTTTTATTCTAGAACAAATGGTTTTACAACAAAGCTGATCTTAAATAGTACATTTCCCCG CTGATAACAGCGCCATCTTCCTTCGACCCCCAGACCAAGGGATCAAAGCTACTGCTCAAT TGAGTTTGACATCAGCTACCGACTTTTAAGGAATCTAGAACAAAGTTCTGGAGCCAGGCC AGAAGTGGTAAAAGATTCAGTTAGCCCCTTCCTCTGTGCTGTGCTGACAGGGAGGGAGCC AGTGACTGGACAATCTATGACCCCAAGTTTGTGGAACGTGGGGCTTCAGCTGAGGGTGGG GTAGTGTGATTTCAGCAGTGTCTCCACCTCCCTGACCCCTGCGCTGCTTTGCTCTGTTGT CACCTCCCGCACAGTGTCGGGACACTGACCGGAAGCCAAACCTGTGCCTGGTGGCCACAG ACAAGACACACGGATCTCCGTGAACCTTGCTGTTGTGCCCTTACCGAGGCCATTGTGCTA CCTGTTGAACAATAAAACCGGTCCTATTTGACTGCGCCCCCATTGTTCAACTGTGACCTC TCGTGTACTCCGCAAAAATGCTTCTATATCTGAGGGATACGCCTAGGCTTTTCAATCCAC TACGCGGGAACCGCGTATCTCCATACATTCCCGTCTTCCTGACCTACTCCCTGTCCCCCT CCAGTACAACCCCGTACACATATCTCCCAACATCCCGCACACCTCGTCCACTAGTCTCCC TATCCCCTCCTCCCCCTCGCAGCCTTCTTCCTTCATTCATCTTGCGTTACTTCGTGTTTT CTAGCAATCTCCCTCTATAGCACCGCTCCTTCCCATATCCCCCCCATTACCTCTCATCCC TCTAACATCCGTTACTTCTCAGTTCTTATTCCCACCCTTGATCCACGTACAATATTACCA TCTCATCATAAAATATTATN |
Restriction Sites | NotI-NotI |
ACCN | NM_022767 |
Insert Size | 2770 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_022767.1, NP_073604.1 |
RefSeq Size | 3134 bp |
RefSeq ORF | 630 bp |
Locus ID | 64782 |
UniProt ID | Q8WTP8 |
Domains | EXOIII |
Gene Summary | Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
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