Apoptosis enhancing nuclease (AEN) (NM_022767) Human Untagged Clone
CAT#: SC324654
AEN (untagged)-Human apoptosis enhancing nuclease (AEN)
CNY 2,400.00
CNY 6,270.00
Product images
CNY 6,281.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | ISG20L1; pp12744 |
Vector | pCMV6-AC |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>OriGene sequence for NM_022767.2
CCGGAAGAGACACGCGGGGCTTCAGGCTGCTGCCCCATTGGAAGATTACTCCCCAGGCTT
CCCTTGCCCCAAGCAGTGAGCTGACTGGAATGGTACCCCGGGAGGCCCCTGAGTCTGCTC AGTGCCTGTGCCCTTCCCTCACCATCCCAAATGCCAAGGATGTGCTTCGGAAGAGGCACA AGAGAAGGAGCCGACAGCACCAGCGGTTCATGGCCCGGAAGGCCTTGCTGCAGGAGCAGG GGCTGCTGAGCATGCCTCCAGAACCAGGGTCCTCCCCACTGCCCACCCCTTTCGGGGCAG CGACAGCAACTGAAGCTGCCAGCAGTGGGAAGCAGTGTCTGAGGGCTGGATCTGGCAGTG CCCCATGCAGCAGAAGGCCTGCTCCCGGGAAAGCCTCAGGGCCCTTGCCCAGCAAGTGTG TGGCTATCGACTGTGAGATGGTGGGCACGGGACCCCGAGGGCGGGTAAGCGAGCTGGCCC GCTGTTCCATTGTGAGCTACCATGGCGATGTCCTCTATGACAAGTACATCAGGCCTGAGA TGCCCATCGCTGACTACCGTACCCGCTGGAGTGGCATCACTCGGCAGCACATGCGCAAGG CTGTCCCCTTCCAGGTGGCCCAGAAAGAGATCCTTAAGCTCCTGAAGGGCAAGGTGGTGG TGGGGCACGCGCTGCACAACGACTTCCAGGCGCTCAAGTATGTCCACCCTCGGAGCCAGA CCCGGGATACCACCTATGTCCCAAACTTCCTCAGCGAGCCCGGCCTCCACACCCGGGCCC GGGTCTCTCTAAAGGACCTGGCCCTGCAGCTGCTGCACAAGAAGATCCAGGTGGGCCAGC ACGGGCACTCATCAGTAGAAGATGCCACGACAGCCATGGAGCTCTACCGGCTGGTGGAGG TGCAGTGGGAACAGCAGGAGGCCCGCAGCCTCTGGACCTGCCCCGAGGACAGAGAACCTG ACAGCAGCACAGACATGGAACAGTACATGGAGGACCAGTACTGGCCCGATGACCTGGCCC ACGGCAGCAGAGGAGGAGCCAGGGAGGCACAGGACAGAAGGAATTGAGAAGGGGGCGGGG CTCCCTGGCTGGGCTTCCGGTGTGGCCGGTAGGAAGTGGGGGCCAGGAGAGCAGCGGGCA CTCCTTCCTGGGCAGGGTGGGGCAGGATGCAGTGAGCCAGCCCCAGGGCCAGAGGAGTTG GGGTCATCTGTTACCTTGACACCCTCTGCACACAGCATAGCCCTCTCTCTCTCCAGGGCT GTTGGTTCTTTCTCCTGACTCCTGTGGTTTTGCTAATGGCACTTTACAGACTCCATGGAG ATGTCAGGTGGACCATCTTCTAGGGCCCAGCAGGAGTAGGGAATGTGCCAACAGACTGCC CAGGTTGCCGTGGCCTTCCCCACCCCCCAGATCTCCTGAGTCATCATGCTGTGCTAATGA AAGGGATCATATCATCCTCTCTGGGGATGGTGGGTGGGGGTGTCAATATCCTGGAGCTCC CTTACCCCAACTCAATGACTTGGGGGTAAAGTTCTCTTCCTTTTGTTGCCTACCTCTTCC TCCACTCATTTGGGTTCAGAATAAACATGCCCTGAAGTTAAAGGGGAGTTAAGTCCTAAA GGAGGCATTTCTTCCCCACCTCCCTGACCTGGAACTCTGGCTACAGCCATTGTAGGAACT CCGTGCCTGGCCTGTCAGCTCCCTGCTAGGCTACAGTGGAATAGCAGAGCCCACAGGCTT CTCGTGGGGAGTTGGCTCCTTAACATTTCTTGGCAACAGAAAGCCCCAGGCACAGCTCAG GGAGGAGGGAAGGCAGGTAAGCTTTGGACGAGAACTGGCATATTTATTTTGACCCAAATC AGGGATTTCCCCAGTCCACCCAGTACTGGGCTCTTAAGCAAAAGTCTGAGAAACAAGACA GTGGTTTGAATTCTGGGGCCTTTGTGTAGGATTGTGCCTGACCTTTATTTATTTATTAAC AGCAGGGCCACTCGTCTAGGGCAGTGGAGTCTGCGTGTCTCCTGGGGCTGGGGCAGGGCA TTGGCAGTTACGCAGTGGCCCTGAACCTGGTCTGGTGCCCCCGAACCTGGTCTGATGCCC CCTCAGCTCTTTGACAATCACTGTGGCTGTTGGGTTTTCTCCTATTTCTAAAAATGTTCT CTTCTTTCCTAAGTGACAGTTTTGAAGTATTGGATAACCAAGAGCTCAGGTCACACAGAC CTTGGAGCCCCATCTTTGCTTGCAGCTTAGCTTTGAGATACTAAGCAAGCGAGGGACTTC ACTCTTGAGCCTGTTTTTTCCTCATCTGTAAAGTGGGGATAGTGGTACGGCCTACCTCAT AGGGTTGTAATGAGCACTAAATGTGAAGTGCTTGGCACAGTGCCTGGCACATGGTGAGCC ACAGCTACTGTGAGTTTCTGTTTATCCCCCTTTTTTTTTTTTTAAGCCCATTGTTTATTC TTTGAGAATTTGTTGTAACTTCTTCAGGATAACACCTGAGTCCACAGGCTGAGCAGCTGT GGCCCAGACAGAACTGCTCCGGCTTGGCTGTTCCAGCAGGTGGGGCGCTGGCCTCGGTGA GGGCACAGCAGCAAGGTTCACGGATATCCGTGTGTCTTGTCTGTGGCCACCAGGCACAGG TTTGGCTTCCGGTCAGTGTCCCGACACTGTGCGGGAGGTGACAACAGAGCAAAGCAGCGC AGGGGTCAGGGAGGTGGAGACACTGCTGAAATCACACTACCCCACCCTCAGCTGAAGCCC CACGTTCCACAAACTTGGGGTCATAGATTGTCCAGTCACTGGCTCCCTCCCTGTCAGCAC AGCACAGAGGAAGGGGCTAACTGAATCTTTTACCACTTCTGGCCTGGCTCCAGAACTTTG TTCTAGATTCCTTAAAAGTCGGTAGCTGATGTCAAACTCAATTGAGCAGTAGCTTTGATC CCTTGGTCTGGGGGTCGAAGGAAGATGGCGCTGTTATCAGCGGGGAAATGTACTATTTAA GATCAGCTTTGTTGTAAAACCATTTGTTCTAGAATAAAACTCAATTGGAAACGTGAAAAA AAAAAAAAAAAAAA |
Restriction Sites | Please inquire |
ACCN | NM_022767 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_022767.2, NP_073604.2 |
RefSeq Size | 3074 bp |
RefSeq ORF | 978 bp |
Locus ID | 64782 |
UniProt ID | Q8WTP8 |
Domains | EXOIII |
Gene Summary | Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
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---|---|---|---|
RC202285 | AEN (Myc-DDK-tagged)-Human apoptosis enhancing nuclease (AEN) |
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RC202285L3 | Lenti ORF clone of Human apoptosis enhancing nuclease (AEN), Myc-DDK-tagged |
CNY 5,890.00 |
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RC202285L4 | Lenti ORF clone of Human apoptosis enhancing nuclease (AEN), mGFP tagged |
CNY 5,890.00 |
|
RG202285 | AEN (tGFP-tagged) - Human apoptosis enhancing nuclease (AEN) |
CNY 4,000.00 |
|
SC112416 | AEN (untagged)-Human apoptosis enhancing nuclease (AEN) |
CNY 2,400.00 |
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