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AXL (NM_021913) Human Untagged Clone
CAT＃: SC112559
AXL (untagged)-Human AXL receptor tyrosine kinase (AXL), transcript variant 1
CNY 6,552.00
| Cited in 6 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ARK; JTK11; Tyro7; UFO |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_021913 edited
GGCGGCTGCTGGGCAGAGCCGGTGGCAAGGGCCTCCCCTGCCGCTGTGCCAGGCAGGCAG TGCCAAATCCGGGGAGCCTGGAGCTGGGGGGAGGGCCGGGGACAGCCCGGCCCTGCCCCC TCCCCCGCTGGGAGCCCAGCAACTTCTGAGGAAAGTTTGGCACCCATGGCGTGGCGGTGC CCCAGGATGGGCAGGGTCCCGCTGGCCTGGTGCTTGGCGCTGTGCGGCTGGGCGTGCATG GCCCCCAGGGGCACGCAGGCTGAAGAAAGTCCCTTCGTGGGCAACCCAGGGAATATCACA GGTGCCCGGGGACTCACGGGCACCCTTCGGTGTCAGCTCCAGGTTCAGGGAGAGCCCCCC GAGGTACATTGGCTTCGGGATGGACAGATCCTGGAGCTCGCGGACAGCACCCAGACCCAG GTGCCCCTGGGTGAGGATGAACAGGATGACTGGATAGTGGTCAGCCAGCTCAGAATCACC TCCCTGCAGCTTTCCGACACGGGACAGTACCAGTGTTTGGTGTTTCTGGGACATCAGACC TTCGTGTCCCAGCCTGGCTATGTTGGGCTGGAGGGCTTGCCTTACTTCCTGGAGGAGCCC GAAGACAGGACTGTGGCCGCCAACACCCCCTTCAACCTGAGCTGCCAAGCTCAGGGACCC CCAGAGCCCGTGGACCTACTCTGGCTCCAGGATGCTGTCCCCCTGGCCACGGCTCCAGGT CACGGCCCCCAGCGCAGCCTGCATGTTCCAGGGCTGAACAAGACATCCTCTTTCTCCTGC GAAGCCCATAACGCCAAGGGGGTCACCACATCCCGCACAGCCACCATCACAGTGCTCCCC CAGCAGCCCCGTAACCTCCACCTGGTCTCCCGCCAACCCACGGAGCTGGAGGTGGCTTGG ACTCCAGGCCTGAGCGGCATCTACCCCCTGACCCACTGCACCCTGCAGGCTGTGCTGTCA GACGATGGGATGGGCATCCAGGCGGGAGAACCAGACCCCCCAGAGGAGCCCCTCACCTCG CAAGCATCCGTGCCCCCCCATCAGCTTCGGCTAGGCAGCCTCCATCCTCACACCCCTTAT CACATCCGCGTGGCATGCACCAGCAGCCAGGGCCCCTCATCCTGGACCCACTGGCTTCCT GTGGAGACGCCGGAGGGAGTGCCCCTGGGCCCCCCTGAGAACATTAGTGCTACGCGGAAT GGGAGCCAGGCCTTCGTGCATTGGCAAGAGCCCCGGGCGCCCCTGCAGGGTACCCTGTTA GGGTACCGGCTGGCGTATCAAGGCCAGGACACCCCAGAGGTGCTAATGGACATAGGGCTA AGGCAAGAGGTGACCCTGGAGCTGCAGGGGGACGGGTCTGTGTCCAATCTGACAGTGTGT GTGGCAGCCTACACTGCTGCTGGGGATGGACCCTGGAGCCTCCCAGTACCCCTGGAGGCC TGGCGCCCAGGGCAAGCACAGCCAGTCCACCAGCTGGTGAAGGAACCTTCAACTCCTGCC TTCTCGTGGCCCTGGTGGTATGTACTGCTAGGAGCAGTCGTGGCCGCTGCCTGTGTCCTC ATCTTGGCTCTCTTCCTTGTCCACCGGCGAAAGAAGGAGACCCGTTATGGAGAAGTGTTT GAACCAACAGTGGAAAGAGGTGAACTGGTAGTCAGGTACCGCGTGCGCAAGTCCTACAGT CGTCGGACCACTGAAGCTACCTTGAACAGCTTGGGCATCAGTGAAGAGCTGAAGGAGAAG CTGCGGGATGTGATGGTGGACCGGCACAAGGTGGCCCTGGGGAAGACTCTGGGAGAGGGA GAGTTTGGAGCTGTGATGGAAGGCCAGCTCAACCAGGACGACTCCATCCTCAAGGTGGCT GTGAAGACGATGAAGATTGCCATCTGCACGAGGTCAGAGCTGGAGGATTTCCTGAGTGAA GCGGTCTGCATGAAGGAATTTGACCATCCCAACGTCATGAGGCTCATCGGTGTCTGTTTC CAGGGTTCTGAACGAGAGAGCTTCCCAGCACCTGTGGTCATCTTACCTTTCATGAAACAT GGAGACCTACACAGCTTCCTCCTCTATTCCCGGCTCGGGGACCAGCCAGTGTACCTGCCC ACTCAGATGCTAGTGAAGTTCATGGCAGACATCGCCAGTGGCATGGAGTATCTGAGTACC AAGAGATTCATACACCGGGACCTGGCGGCCAGGAACTGCATGCTGAATGAGAACATGTCC GTGTGTGTGGCGGACTTCGGGCTCTCCAAGAAGATCTACAATGGGGACTACTACCGCCAG GGACGTATCGCCAAGATGCCAGTCAAGTGGATTGCCATTGAGAGTCTAGCTGACCGTGTC TACACCAGCAAGAGCGATGTGTGGTCCTTCGGGGTGACAATGTGGGAGATTGCCACAAGA GGCCAAACCCCATATCCGGGCGTGGAGAACAGCGAGATTTATGACTATCTGCGCCGGGGA AATCGCCTGAAGCAGCCTGCGGACTGTCTGGATGGACTGTATGCCTTGATGTCGCGGTGC TGGGAGCTAAATCCCCAGGACCGGCCAAGTTTTACAGAGCTGCGGGAAGATTTGGAGAAC ACACTGAAGGCCTTGCCTCCTGCCCAGGAGCCTGACGAAATCCTCTATGTCAACATGGAT GAGGGTGGAGGTTATCCTGAACCCCCTGGAGCTGCAGGAGGAGCTGACCCCCCAACCCAG CCAGACCCTAAGGATTCCTGTAGCTGCCTCACTGCGGCTGAGGTCCATCCTGCTGGACGC TATGTCCTCTGCCCTTCCACAACCCCTAGCCCCGCTCAGCCTGCTGATAGGGGCTCCCCA GCAGCCCCAGGGCAGGAGGATGGTGCCTGAGACAACCCTCCACCTGGTACTCCCTCTCAG GATCCAAGCTAAGCACTGCCACTGGGGAAAACTCCACCTTCCCACTTTCCCACCCCACGC CTTATCCCCACTTGCAGCCCTGTCTTCCTACCTATCCCACCTCCATCCCAGACAGGTCCC TCCCCTTCTCTGTGCAGTAGCATCACCTTGAAAGCAGTAGCATCACCATCTGTAAAAGGA AGGGGTTGGATTGCAATATCTGAAGCCCTCCCAGGTGTTAACATTCCAAGACTCTAGAGT CCAAGGTTTAAAGAGTCTAGATTCAAAGGTTCTAGGTTTCAAAGATGCTGTGAGTCTTTG GTTCTAAGGACCTGAAATTCCAAAGTCTCTAATTCTATTAAAGTGCTAAGGTTCTAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_021913 unedited
GTCAACATTTNGTAAACGACTTACTATAGGGCGGCCGCGAAATTCCCGGATGGCGGCTGC TGGGCAGAGCCGGTGGCAAGGGCCTCCCCTGCCGCTGTGCCAAGCAGGCAGTGCCAAATC CGGGGAGCCTGGAGCTGGGGGGAGGAAAAAAGCCATCACTCAAAGTGCACCACACATAAC CCATAAATGAAAAAGAATAAACACAAAAAACTTATATCTTCTAAACAAAATACCACAAAT TTTCGAGGGGAAAAACATCACAAAACCCAAACCACACCACATCCATTAAAAAGAAAATAT TACTCCAATATATTAAAACAAAATCACAAAAAACAGCAACAAAACAAGACACAAATATAT AACTAAAATAACACAATAAACAATTAAACACACAAATACATAAAACAAATACACCCCCTA CAACAACACAGACACAGCCAAAAAAAAAACAATATGAAATACAAAAAAAACATAAAGAAC ATAAGCTAACTAAACAAATAAAAGAAAAGAAAAACCGACAATTTCATCAAAAAAAATAAC AAAAAAAACGAAACACAAACAAATATACAACCCACACACACAAAAAACCAAAAACTACTC ACAAAAAAAAAACAAACAAAAGAAACATCCAACCACAGAACCATCAAGTATATAAAATAA ACAACTTTATAACACAACCAACATCAATAGACATAACACCAAAAAAATTAAATAATCAAA GAAAAACAACAACAATCAAATTCCCACTCCAGCAACGAAAAGATTAACTAAACCAACAAC AAAACAAGACGTAAAATACAATAAAACAAAAAACTAAACAAATAGAAAAAAAAAATAAAT CATATAAATTACAAATGTCCAAAAACTGATCACAAACGATAAAACTCAACATAACCATAA ACAACACCACCAAAACAATAACAAACACTTCACACACTAACAACCAAATAAATAACAAAC AAGTC |
| Restriction Sites | Please inquire |
| ACCN | NM_021913 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021913.2, NP_068713.2 |
| RefSeq Size | 4750 bp |
| RefSeq ORF | 2685 bp |
| Locus ID | 558 |
| UniProt ID | P30530 |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Gene Summary | The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). |
Citations (6)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Engineered AXL‑ECD‑Fc variants that abolish the AXL/Gas6 interaction suppress tumor cell migration
,Duan, Y;Hu, B;Qiao, C;Luo, L;Li, X;Wang, J;Liu, H;Zhou, T;Shen, B;Lv, M;Feng, J;,
Oncol Lett
,PubMed ID 31186805
[AXL]
|
|
Aptamer-miR-34c Conjugate Affects Cell Proliferation of Non-Small-Cell Lung Cancer Cells
,Russo, V;Paciocco, A;Affinito, A;Roscigno, G;Fiore, D;Palma, F;Galasso, M;Volinia, S;Fiorelli, A;Esposito, CL;Nuzzo, S;Inghirami, G;de Franciscis, V;Condorelli, G;,
Mol Ther Nucleic Acids
,PubMed ID 30340138
[AXL]
|
|
Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL
,Iaboni, M;Russo, V;Fontanella, R;Roscigno, G;,
Molecular Therapy nucleic acid
,PubMed ID 27111415
[AXL]
|
|
Functional Consequences of AXL Sequence Variants in Idiopathic Hypogonadotropic Hypogonadism
,Salian-Mehta, S;Xu, M;Knox, A;Plummer, L;Slavov, D;Taylor, M;Bevers, S;Hodges, R;Crowley, W;Wierman, M;,
J. Clin. Endocrinol. Metab., Jan 2014.
,PubMed ID 24476074
[AXL]
|
|
AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma
,M Z Xu, S W Chan, A M Liu, K F Wong, S T Fan, J Chen, R T Poon, L Zender, S W Lowe, W Hong, et al.,
Oncogene (15 November 2010) doi:10.1038/onc.2010.504 Original Article
[AXL]
|
|
AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma
,null,
Oncogene
,PubMed ID 21076472
[AXL]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206431 | AXL (Myc-DDK-tagged)-Human AXL receptor tyrosine kinase (AXL), transcript variant 1 |
CNY 6,552.00 |
|
| RC206431L1 | Lenti ORF clone of Human AXL receptor tyrosine kinase (AXL), transcript variant 1, Myc-DDK-tagged |
CNY 8,952.00 |
|
| RC206431L2 | Lenti ORF clone of Human AXL receptor tyrosine kinase (AXL), transcript variant 1, mGFP tagged |
CNY 8,952.00 |
|
| RC206431L3 | Lenti ORF clone of Human AXL receptor tyrosine kinase (AXL), transcript variant 1, Myc-DDK-tagged |
CNY 8,952.00 |
|
| RC206431L4 | Lenti ORF clone of Human AXL receptor tyrosine kinase (AXL), transcript variant 1, mGFP tagged |
CNY 8,952.00 |
|
| RC600072 | AXL (DDK-His-tagged)-Extra Cellular Domain Clone of Homo sapiens AXL receptor tyrosine kinase, transcript variant 1, Signal peptide (1-25) plus EC domain (26-451) |
CNY 3,656.00 |
|
| RG206431 | AXL (tGFP-tagged) - Human AXL receptor tyrosine kinase (AXL), transcript variant 1 |
CNY 8,152.00 |
|
| SC323559 | AXL (untagged)-Kinase deficient mutant (K567M) of Human AXL receptor tyrosine kinase (AXL), transcript variant 1 |
CNY 7,220.00 |
